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本帖最后由 细胞海洋 于 2013-9-22 11:59 编辑 # B# I" G: v8 Q, c o$ z1 N& h- t
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20 September 2013 % R7 A+ l! G" T z8 ~
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COVER Immunostained fluorescence microscopy image of a biomarker of endogenous withdrawal (phosphorylated extracellular regulated kinase, red) that increases in mouse spinal cord neurons (green) during opioid receptor blockade (image width: 250 micrometers). Inflammation or injury to the skin causes μ-opioid receptors to become constitutively active, which leads to long-term relief from chronic pain, but at the expense of endogenous opioid dependence. See page 1394. Image: Suzanne Doolen, Greg Corder, and Brad Taylor/University of Kentucky$ @' J8 [) I- e8 w u1 x4 b
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