《科学》[Science]13年10月11日出版pdf全文

孙弘博

False-colored scanning electron micrograph of erythrocytes
7 a+ d0 O1 p% z! [  u9 ^( V- s(diameter ~7 micrometers). Sickle cell disease results from an
" g. I5 n! L6 V& G9 C6 linherited defect of adult hemoglobin, the oxygen-carrying
* ^1 i+ q% E/ X) P: zmetalloprotein constituent of erythrocytes. Common genetic variation
6 Q  s5 Y4 o, ~# m6 o, Iassociated with sickle cell disease severity modulates an adult-stage
5 ~' R' c% ]: [' terythroid enhancer element of the BCL11A gene. Disruption of this& ~6 w! O. e- ~2 v
element could ameliorate the disease by reestablishing expression
- |, C9 b% Q- G2 Hof fetal hemoglobin. See pages 206 and 253.
! |# g$ `8 S) c  R0 Q& j* c; H+ v
7 \, p8 ^) C3 \! G9 P
回复有免费下载链接
/ b1 E( o( W  y5 s  i4 C% f5 M; o" \3 c/ F4 b4 V2 u$ N  b

游客，如果你要查看本帖隐藏内容请回复

懵懂干细胞

感谢楼主分享

dawnmed

thank you for sharing

xiangchou812

thanks for sharing

sgd118

感谢楼主的分享

gghywtfz

看看哦

CoolCell

看看

pujvzi

Thanks very much!

zorro

thanks

sea200k

lz 是好人啊( d% Y# _' b( |- a( B