化身健身男神？干细胞来帮你！

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来源：生物谷 2014-07-30 18:18
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2014年7月30日讯 /生物谷BIOON/ --拥有一个完美的身材是时下很多年轻人锻炼的目标，为了拥有八块腹肌，许多人进行了“艰苦卓绝”的锻炼。你可曾想过未来某一天通过注射干细胞就可以帮助你更好更快的达成这一目标？
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$ K% A* Y! z7 o$ q* Z最近来自伊利诺伊大学的研究人员发现间充质干细胞可能能加速人体肌肉的形成。在动物实验模型上，研究人员将这类干细胞注射到小鼠体内，经过强化锻炼后小鼠的骨骼肌组织明显增加。这一研究被发表在Medicine & Science in Sports & Exercise杂志上。间充质干细胞具有分化为人骨骼组织如骨髓、脂肪和软骨组织的潜能，此项研究证明，间充质细胞能够在一定条件下分化形成骨骼肌细胞的前体细胞，一种名为卫星细胞（Satellite cells）的细胞类型。而经过进一步锻炼，这种细胞就会分化形成骨骼肌细胞，对骨骼肌组织进行强化。
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& M* C) C3 H$ M, {( ?) K: y科学家希望能够利用这一方法治疗与骨骼肌有关的一系列疾病。不过广大男性朋友应该注意了，即使以后这一方法进入临床，想要拥有完美身材，化身男神，健康的生活习惯才是王道！（生物谷Bioon.com）
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4 q+ B% h$ g' l' X) F详细英文报道：
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( x: g4 I* R' c! m' @4 b7 ~- z* GMesenchymal stem cells (MSCs) may eventually be able to grow and strengthen muscles in humans, according to researchers at the University of Illinois. In mice, an injection of such stem cells helped rejuvenate skeletal muscle after exercise.
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5 w( @8 s' |' p% N7 k. I2 qThe treatment, which was injected directly in the mice's legs, may someday be used in humans to combat age-related declines in muscle structure and function.
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2 E2 Y8 t2 X# i  y! u3 p# z. UMSCs are attractive to scientists because of their ability to make several types of cells that appear in human skeletal tissues, such as cartilage, bone and fat.* M& q) O' N% U9 T. D
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University of Illinois researchers injected the MSCs before several bouts of eccentric exercise--designed to simulate the lengthening contractions performed during resistance training in humans that cause mild muscle damage.  E- g4 d8 ]. U# N5 x0 @1 N4 |

4 k( @( o. s# l' T" x1 gResearchers detailed their findings in the journal Medicine & Science in Sports & Exercise, showing that the injection increased the rate of repair and boosted the growth and strength of the leg muscles in the exercising mice.3 S2 P4 o3 U) Q  z* \

& Y9 u$ t) [# l. |MSCs, which occur naturally in the body, seem to stimulate muscle precursor cells, called satellite cells, spurring tissue repair after injury, according to the study. Once these satellite cells are activated, they fuse to the damaged muscle fibers and form new fibers to rebuild muscle and improve strength., t# m: {* d+ W
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"Satellite cells are a primary target for the rejuvenation of aged muscle, since activation becomes increasingly impaired and recovery from injury is delayed over the lifespan," said University of Illinois kinesiology and community health professor Marni Boppart, who led the research, in a university news story. "MSC transplantation may provide a viable solution to reawaken the aged satellite cell
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8 l+ s) {0 m. MMesenchymal Stem Cells Augment the Adaptive Response to Eccentric Exercise. }7 v: M9 Z7 Y8 P. A' t
Medicine & Science in Sports & Exercise，Post Acceptance: June 5, 2014; \, b% _7 ^; K. ]3 {, t3 @
doi: 10.1249/MSS.0000000000000405
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