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回复 yz2003can 的帖子7 _( ?6 D% ]: c/ r/ D
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Gene Ther. 2010 Oct;17(10):1206-13. doi: 10.1038/gt.2010.91. Epub 2010 Jun 17.
, Y. U) C2 \$ \* ^7 E7 TAdoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc 'spacer' domain in the extracellular moiety of chimeric antigen receptors avoids 'off-target' activation and unintended initiation of an innate immune response.
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