标题: PDF：Statistical Bioinformatics For Biomedical and Life Science Researchers [打印本页] 作者: lifescience1 时间: 2010-6-19 15:22 标题: PDF：Statistical Bioinformatics For Biomedical and Life Science Researchers
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PREFACE" S, }$ @: k7 \6 j8 [: I
This book has been constructed primarily as a textbook for a one- or two-semester 4 Z0 N' @. A" u+ T- L$ T9 Dcourse in statistical bioinformatics. We hope that it will first serve as a comprehensive. B) @) T+ j3 c9 ]5 B
introduction to a broad range of topics in this area for life science students and ( |: M+ H* l$ Z$ L5 G& I% v* d: {- fresearchers who are motivated to learn statistical analysis concepts and techniques4 q1 ~6 V% G# l5 W3 _
in bioinformatics. Statistical and quantitative science audiences who have not yet & W! M# Z5 m) l# G& G3 u3 `2 d- T7 Wdealt with challenging statistical issues in recent information-rich biological and biomedical T6 s: s6 @5 e7 D' v
data analysis may also benefit from this book by efficiently reviewing the % G2 n: I- A! a7 y% z1 d' odifferent statistical concepts and techniques in such analyses. In particular, the four; D$ b4 f- j: m, ~0 }* Y' ]. c N
separate blocks in this book—statistical foundation, high-dimensional analysis,9 k! V7 N9 m6 Z, z( w. S3 F
advanced topics, and multigene systems analysis—can be somewhat independently / [' X2 L5 y+ a U" Istudied and taught in a course based on relevant needs and time restrictions for an + c- T4 B, _* |$ g1 U; ieffective learning purpose.! b! p7 R$ J) f4 F* i
A similar outline as organized in this book has been used for several years in a n! v3 p8 F( Y/ v9 a, }one-semester graduate course which is open to students with diverse backgrounds at 3 q) y% f( X& t8 c2 hthe University of Virginia. By publishing this book, we felt that these contents 7 r! x! d3 v* I& l: b" Z' D7 V5 gcould be significantly enhanced by direct contributions of more specialized experts% S ^' W: I( h2 ^: k& q
in the broad field of bioinformatics. In this multiauthor book, we have yet tried to 6 U) n. O' `4 v; hmaintain the need of a high-level mathematical and statistical understanding at a minimum. " V5 B) V7 X5 u; }Readers of this book are thus assumed to have not much more than a basic college % Y1 t, y+ T$ icalculus level of mathematical understanding. A knowledge of matrix algebra$ A9 G4 X, K+ P. ^( b
would also be useful but is not a prerequisite. " f5 [ C+ C, [* mThis book is certainly a tribute to the contributions and support of many people. % r& u; v. f7 v3 p' \. pAcknowledgments are first due to the succeeding life science editors of JohnWiley & 5 ]/ U! u7 B" N4 @9 V7 mSons: Luna Han, Thomas Moore, and Karen Chambers.Without their continuous support 3 j+ p1 a R. M. Nand encouragement, the publication of this book would not have been possible. m' T! f% d* [
Also, all the efforts made by the expert authors who were willing to participate in9 i G7 a1 S: o4 u+ D% \
this book should be highly acknowledged for its successful completion. Finally, the 6 P% C' J$ e; Zstudents who have taken this initial course and provided valuable feedback on various 8 ]5 r, Z# h. V+ g; R( c. ktopics in this area over the last several years are also significant contributors to the) A2 R0 z* _+ a4 p8 z( f8 |
current form of the book. The preparation of this book was supported in part by the & g& l1 ~# ]. k; G& t- H/ N. L( X$ z, jNational Institutes of Health Research Grant R01 HL081690., R7 N% ]* b4 Q% W5 W9 g
J. K. LEE * }9 f' \2 O! R6 FDivision of Biostatistics and Epidemiology2 Z* F9 s, R+ Q3 A) A! O" W7 E
Charlottesville, Virginia $ v, |0 {6 X$ z8 |1 c) sxi ( v7 | U& ~* D" b& |: U9 B; @' l 3 x5 X, N# ~; N1 Q4 w! _0 |/ \作者: sunyucheng 时间: 2010-6-19 22:03
