9 G0 m2 v1 X* V* O+ R非编码RNA与P53介导的细胞凋亡： @& F" o+ m( C+ m6 f/ B, Q) u+ G" V+ s) `6 J% y- q/ P
Record Number: 1065 ( A% B: X+ w: m" A' E8 IAuthor: A. M. Barsotti and C. Prives) m3 s! x3 b2 K) t0 w% ^) q4 w) ^- R) F
Year: 2010 ! N, V- \/ c: }2 mTitle: Noncoding RNAs: The Missing "Linc" in p53-Mediated Repression 4 h2 r4 S- }- w9 P- z cJournal: Cell5 i! f1 @4 n9 j; W) F3 }0 A2 A; U
Volume: 142 . W6 K. ?0 g! w! q% _. r0 ]Issue: 3* f( \: _9 W4 o2 F% ~1 {" z' j
Pages: 358-360 7 o2 W9 I# R3 A# FEpub Date: 2010/08/10$ @: B5 d4 y5 m1 h
Date: Aug 6 2 A& {# T5 S' `0 X- a3 @2 q ^ U) f
* a# h& z) K v1 m; zNoncoding RNAs: The Missing “Linc” in p53-Mediated Repression: g: C, b8 k0 q. H$ }- N
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The tumor suppressor protein p53 coordinates the cellular response to stress through regulationof gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a newplayer in p53-mediated repression of genes involved in apoptosis.