Non-Viral Gene Therapy8 g- q0 M; C5 ?- H
Edited by: Xu-bo Yuan ; C/ o% S6 ^* S" d' q+ F" e0 G% C[attach]35236[/attach] ( o2 z) {; r, k+ C/ \9 }9 E- t: I4 Y" j5 r3 A3 i# R$ I
ISBN 978-953-307-538-9, Hard cover, 696 pages& }5 r$ u9 M0 r% ^
Publisher: InTech* b# y, I. Y- d6 _: U( q' y; q( q
Publication date: November 20118 F) `, M. C4 K' s
Subject: Gene Therapy ' z7 k# S5 G# `7 B% n . o: K: s( S7 |This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation. # |7 \5 F3 ?0 q6 ~ + v. I- I6 H: V2 u8 k `Table of Contents5 w1 Z8 l# N- ^2 {
Non-Viral Gene Therapy Vectors Carrying Genomic Constructs. P. Z7 P, C0 |- z; `4 G, v& [
+ A% c' B; o1 s5 w$ T% F1 TNon-Viral Delivery Systems in Gene Therapy and Vaccine Development % V2 B F# ?/ b8 \( C7 a$ E' W; {- V: M7 j4 P! M$ {2 ]7 c
Gene Delivery Systems: Tailoring Vectors to Reach Specific Tissues% h5 \# \$ N3 S- t2 a6 W- P) E
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Investigation of Transfection Barriers Involved in Non-Viral Nanoparticulate Gene Delivery in Different Cell Lines7 i" a1 l8 ^1 s: Y( x: k9 F0 ^/ O; y
: o+ K, `$ c8 J2 D4 hThe Mechanical Agitation Method of Gene Transfer for Ex-Vivo Gene Therapy 7 A5 M6 v8 @2 P" t- c, }' |/ K5 e w% X. ^6 }: M
Gene Therapy of Some Genetic Diseases by Transferring Normal Human Genomic DNA into Somatic Cells and Stem Cells from Patients# n1 N7 R5 h& [8 D
" v, K' e* ]5 I, d" c% A8 JNon Viral Gene Transfer Approaches for Lysosomal Storage Disorders$ j6 k+ f0 C6 U
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DNA Vaccination by Electrogene Transfer 1 ^1 Z% ~ R; F5 h/ o0 ?) i2 H 7 l$ q1 v7 V w2 Q0 l$ w0 T3 D" @6 nGene Delivery with Ultrasound and Microbubbles6 h* M* M/ M7 \0 k' i9 d7 O
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Ultrasound-Mediated Gene Delivery+ c, \ s3 Z+ K% ^6 { R
* }# j% P a" k, |2 X$ BPolyamine – Lipid Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer Activity! l6 s5 A# B1 { W& c7 N5 t2 Y
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Technological Aspects of Scalable Processes for the Production of Functional Liposomes for Gene Therapy ' c) m) W6 P; {( k, M( o# B; [+ D# Y& M; F1 O* q' b
Cationic Liposomes in Different Structural Levels for Gene Delivery ) A9 p: z1 C8 d0 y1 z |9 r: B/ h1 K; w$ _Neutral Liposomes and DNA Transfection3 x T6 c. p' h2 T9 Q$ w
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Non-Viral Gene Delivery Systems Based on Cholesterol Cationic Lipids: Structure-Activity Relationships6 d: H6 V0 j, Q1 u
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Polycation-Mediated Gene Delivery: The Physicochemical Aspects Governing the Process( ` ^2 Z4 _ b! g- W
. d# H: w8 d+ Z6 J% K! {Medical Polymer-Based Gene Therapy & L. T# d& \, L/ F2 J/ Y2 w$ c) p) N% D9 F% L4 ?
Chitosan and Its Modifications: Are They Possible Vehicles for Gene Therapy?: m( ^! n! n k' A9 C
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Chitosan-DNA/siRNA Nanoparticles for Gene Therapy , I( U6 R; L- n" x 3 Z2 v5 c) S) wToxicity of Polymeric-Based Non-Viral Vector Systems for Pulmonary siRNA Application& I6 R/ M V; P( L6 X( H
/ s! f8 D: K( j( B( D1 D. a2 wPAMAM Dendrimer as Potential Delivery System for Combined Chemotherapeutic and MicroRNA-21 Gene Therapy * S9 m* s/ O# c& @9 j# w7 H G7 a" b0 J1 [; c4 }
Nanomedicine Based Approaches to Cancer Diagonsis and Therapy! W& y3 K' Y3 p# H
6 s; @$ h. Q5 r5 t6 K. p9 e% B! @2 EToxicogenomics of Nonviral Cationic Gene Delivery Nanosystems % f- h0 Z' V- c7 ?, g 4 |" f+ C8 h! j: D; L, e4 A9 dNano-Particulate Calcium Phosphate as a Gene Delivery System " n0 R5 C J, A, G+ v: Y X7 [2 L6 K
Modular Multifunctional Protein Vectors for Gene Therapy7 l( s& Y5 N! E! B/ n& q1 d
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Peptides as Promising Non-Viral Vectors for Gene Therapy / o- M* i0 D1 [4 E) A0 C7 i( D; z' M; ]
Binding of Protein-Functionalized Entities onto Synthetic Vesicles! P2 |9 x3 E, o$ V
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Targeting TRAIL Receptors with Genetically- Engineered CD34+ Hematopoietic Stem Cells+ @% C# s' D- b/ D
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Pyrrole-Imidazole Polyamides for Gene Therapy: Bioanalytical Methods and Pharmacokinetics" A# d/ a$ a: A; d% T
5 F5 k. F& g8 L9 U 作者: dulaiyouyu 时间: 2011-11-8 14:54
咦咦。中国人编的哈。是中文就好了。。。作者: tjbone 时间: 2011-11-8 15:08
看一看了！！！！！！作者: aminhair 时间: 2011-11-8 16:54
kankan / M+ v4 b$ i" m) I% k9 U 作者: jieniao1 时间: 2011-11-8 17:15