; i( c$ ^! t$ {5 Y) x/ P 4 g. L7 W$ G; E; u5 X4 s9 V Volume 78, Issue 4On the cover: Neural networks control 8 O- p" q L' ^+ |, _3 nintrinsic encoding of the circadian clock. Circadian pacemaking in the % f" u G; A& f% x) y5 gsuprachiasmatic nucleus (SCN) depends on cell-autonomous clocks and % C3 d% h! R* Z2 |+ k. `( P
intercellular properties, with the latter still poorly understood. In this issue . \5 }7 ^( e/ U. B$ c- _$ k
of Neuron, Brancaccio et al. (pages 714–728) shed light on circuit-level 4 @+ y- B P' j9 m0 o. }! y: [$ e8 Xencoding of circadian time, showing that specific activation of Gq-Ca2+ axis in ' m0 N: X5 I: s
restricted SCN neuronal subpopulations reprograms encoding of circadian time by " Z. c6 G7 G. p! U9 c+ gthe entire circuit. This circuit-wide reprogramming requires intrinsic VIPergic 4 I$ Y4 k% |7 J. Y: U
connectivity. Concept by Marco Brancaccio; cover illustration by Joanna % p* F4 F& l D: C5 m' u. S5 q, ?' `
Westmoreland. 3 T' S- U: n% F) z2 D. @' e) c# W$ _# B' {7 d- | 作者: tempo 时间: 2015-6-14 16:01
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