|
- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
|
本帖最后由 细胞海洋 于 2012-12-17 10:47 编辑
/ L' l0 W6 W; H8 R0 J3 [9 Q0 Q) G/ Q% r, P9 K
 ! r: U7 k: A* S& R ~' m' P
$ Y# E3 ?. e# w2 K
At the end of cell division in animal cells, the mother cell splits into two daughter cells and partitions segregated chromosomes in a process called cytokinesis. The mitotic spindle controls cytokinetic events at the plasma membrane, but the mechanisms connecting these two macrostructures have been unclear. Mark Petronczki and colleagues now present a structural and functional analysis that identifies centralspindlin, a protein complex in the spindle midzone and midbody, as a missing link between the mitotic spindle and the plasma membrane — a link that secures the final cut during cytokinesis. The authors identify a domain in the MgcRacGAP subunit of centralspindlin as a tether that binds to phosphoinositide lipids in the plasma membrane. On the cover, a fluorescent light micrograph of a cell in the metaphase stage of mitosis. (Torsten Wittmann/Science Photo Library)
* |6 n9 H6 K& G2 ?/ ^ E# J3 x) O# j8 [2 ^! ]
. i. I* x; X% T* ]6 l) V[hide][/hide] |
附件: 你需要登录才可以下载或查看附件。没有帐号？注册
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|
发表于 2012-12-15 14:11
