iPS、胚胎干与直接转分化的“三国演义”

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$ b( K1 D' ]% S, E9 @3 U人ES无法用四倍体互补实验。
0 V2 \, X/ t3 x% \; g9 A" C最近Rudolf Jaenischa发了一篇Human embryonic stem cells with biological and+ y/ D+ a/ t, t
epigenetic characteristics similar to those of mouse ESCs的文章。, e7 h) ^0 u( l. _5 _* E; `9 B
通过ectopic induction of Oct4, Klf4, and Klf2 factors combined with LIF and inhibitors of glycogen synthase kinase 3β
) c& q* @8 f' k- C0 Z(GSK3β) and mitogen-activated protein kinase (ERK1/2) pathway，是hES与mES达到比较类似的程度。: y  C4 h" O! C; j! Z: M7 F
那可不可以利用这种方法，来验证hES和hiPS多能性的标准？