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本帖最后由 细胞海洋 于 2011-8-20 22:02 编辑 : T+ w3 v8 u# ^! p) r
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0 U c" u0 ~. o目录:
5 ^$ b; y t1 E' B K9 P0 qIn This Issue
7 P- o0 n6 P! Z+ z IIn This Issue p489 ; S( A4 {" o5 x+ o8 n: ~
, { ~$ x) y; U; N! ?3 ~& z9 \Select
4 }. J% w2 U& N5 q# {Remote Control: The Brain and Beyond p493 2 g( R6 T: O x6 X% T8 M2 @
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Previews
% t9 W7 v/ W% ?4 _7 P' ]6 l5 gTranscription Factor Loading: Please Take My Place! p497 : ]; Y K g- y( U9 L
Markus Stratmann, Ueli Schibler
, d9 C& P/ W) X9 h* e* FTravel Notes from the Equatorial Circle p499
% V% w# Z8 K5 \, }' |Andrea Musacchio+ H {/ k& j/ G! y9 ?' @4 Y& |
Elongated Membrane Zones Boost Interactions of Diffusing Proteins p501 ' Z# V; Y* o- Y4 u! T# M
Joshua Zimmerberg, Samuel T. Hess# q! h) m3 g" X' V
Meeting the (N-Terminal) End with Acetylation p503 6 X3 }+ x: P: E" X9 i
Joshua L. Andersen, Sally Kornbluth
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5 n2 C: X: d, k' U+ U3 sCommentary( h5 n4 P6 \* }2 C U4 I
Organizing Graduate Life Sciences Education around Nodes and Connections p506 " x/ k+ R4 W/ l. m4 w' B( J8 \, f
Jon R. Lorsch, David G. Nichols
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4 k2 U2 B0 k% ?4 Y; v: C) aPerspective1 C2 ?7 u" f0 P. Q6 h7 J c. x
Mechanisms for the Inheritance of Chromatin States p510 $ I0 B( b$ Z4 ~! S: A- ^7 y1 B' U7 x
Danesh Moazed, _8 S9 i b- G( K2 c
" i4 F( U1 ?- I( y: o) EArticles
2 j& {5 Z2 b' OReconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells p519
4 C8 N0 s. p9 zKatsuhiko Hayashi, Hiroshi Ohta, Kazuki Kurimoto, Shinya Aramaki, Mitinori Saitou
+ K& k- A, v3 K+ k9 a \Linking RNA Polymerase Backtracking to Genome Instability in E. coli p533
- o5 s5 _& p* }. x/ e! mDipak Dutta, Konstantin Shatalin, Vitaly Epshtein, Max E. Gottesman, Evgeny Nudler* e3 B! d' T* E! v
Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism p544 * }0 p& {. U) |, T( a; f8 s/ T
Ty C. Voss, R. Louis Schiltz, Myong-Hee Sung, Paul M. Yen, John A. Stamatoyannopoulos, Simon C. Biddie, Thomas A. Johnson, Tina B. Miranda, Sam John, Gordon L. Hager
4 L6 ?# @: n6 hThe Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly p555 7 m8 Y% |/ m! C$ @2 I1 I: ^
Valentin Magidson, Christopher B. O'Connell, Jadranka Lon?arek, Raja Paul, Alex Mogilner, Alexey Khodjakov8 W, s* Q9 Y1 X
Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes p568 $ z6 i' i8 w+ D0 s. R
Tomoya S. Kitajima, Miho Ohsugi, Jan Ellenberg8 _ X( S, d. w
Rapid Microtubule Self-Assembly Kinetics p582 ( M# ~7 L. N! z% h
Melissa K. Gardner, Blake D. Charlebois, Imre M. Jánosi, Jonathon Howard, Alan J. Hunt, David J. Odde
, N4 ~, W( a5 q bCytoskeletal Control of CD36 Diffusion Promotes Its Receptor and Signaling Function p593
3 {$ y: C( Q$ nKhuloud Jaqaman, Hirotaka Kuwata, Nicolas Touret, Richard Collins, William S. Trimble, Gaudenz Danuser, Sergio Grinstein
+ _7 ^" f) N% x1 L: TMetabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival p607
8 X7 p& N2 l9 O7 s" x$ ~" ]/ N' A! nCaroline H. Yi, Heling Pan, Jan Seebacher, Il-Ho Jang, Sven G. Hyberts, Gregory J. Heffron, Matthew G. Vander Heiden, Renliang Yang, Fupeng Li, Jason W. Locasale, Hadar Sharfi, Bo Zhai, Ricard Rodriguez-Mias, Harry Luithardt, Lewis C. Cantley, George Q. Daley, John M. Asara, Steven P. Gygi, Gerhard Wagner, Chuan-Fa Liu, Junying Yuan" o3 o% @9 T @& P: e8 V
Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons p621 8 P' \4 b' B, Q. ?& l: z7 u! B( d
Christoph Thomas, Ignacio Moraga, Doron Levin, Peter O. Krutzik, Yulia Podoplelova, Angelica Trejo, Choongho Lee, Ganit Yarden, Susan E. Vleck, Jeffrey S. Glenn, Garry P. Nolan, Jacob Piehler, Gideon Schreiber, K. Christopher Garcia* N9 B$ O1 t- Z. U( w5 [) X
2 ^9 y2 I! `) p- u" v) tTheory8 J; @7 M9 X# v9 L1 z
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells p633 ( V" W% u" l7 o4 y# K
Piyush B. Gupta, Christine M. Fillmore, Guozhi Jiang, Sagi D. Shapira, Kai Tao, Charlotte Kuperwasser, Eric S. Lander
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$ O3 d W, c/ [Resource
3 A. f0 L! c4 H+ a9 UThe Human Mitochondrial Transcriptome p645
- H* Y. h5 w" J2 m9 G1 hTim R. Mercer, Shane Neph, Marcel E. Dinger, Joanna Crawford, Martin A. Smith, Anne-Marie J. Shearwood, Eric Haugen, Cameron P. Bracken, Oliver Rackham, John A. Stamatoyannopoulos, Aleksandra Filipovska, John S. Mattick
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; O2 a$ O T+ b& @6 J, c! e1 d* QErratum
7 V7 u) b( J# f/ l# e: @Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations p659 ) H- V- U+ ]/ Z% X D2 U% Q
Frank Soldner, Josée Laganière, Albert W. Cheng, Dirk Hockemeyer, Qing Gao, Raaji Alagappan, Vikram Khurana, Lawrence I. Golbe, Richard H. Myers, Susan Lindquist, Lei Zhang, Dmitry Guschin, Lauren K. Fong, B. Joseph Vu, Xiangdong Meng, Fyodor D. Urnov, Edward J. Rebar, Philip D. Gregory, H. Steve Zhang, Rudolf Jaenisch; t- T @7 ~ b3 ]9 ~8 c* ?8 T
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Snapshot
: H0 B5 ?6 O# d. U, j# hSnapShot: Dendritic Cells p660 ) ]' G2 C) t7 o6 H
Juliana Idoyaga, Ralph M. Steinman
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