European Heart Journal：保持冷静—愤怒会引发的严重心脏病发作

佰通生物

原文地址链接：European Heart Journal：保持冷静—愤怒会引发的严重心脏病发作   更多精彩新闻请点击：佰通生物
      悉尼大学研究人员最近调查急性情感爆发和严重的心脏病发作的高风险之间的联系后发现：在强烈愤怒后两小时内心脏病发作的风险比正常情况高出了8.5倍。研究结果证实了以前的假设，相关研究，甚至电影的情节—即强烈的愤怒发作可以变为心脏攻击。这篇研究发表在2月刊的European Heart Journal。

      在这项研究中，按1~7的梯度划分愤怒值，“愤怒”的设定是需要达到5或5以上，具体表现包括“很生气，身体紧张，握紧拳头或牙齿，随时爆发”，到“激怒，一发不可收拾，摔物品“。低于这个水平的愤怒并没有与风险增加相关。研究人员表示：“触发这些一阵强烈的愤怒主要与与家庭成员争论（29％），与其他人争论（42％），工作愤怒（14％）和驾驶愤怒（14％）相关。

      这项研究主体是疑似有连续心脏病发作的患者。在医院的造影检查证实却有急性冠脉堵塞后，研究人员采访了他们（共313名）在发病前48小时内活动，并记录活动频率进行比较。

      虽然愤怒触发心脏病发作的几率仅仅是2％左右，可是愤怒过后发生心脏病的危险性比正常行为后发作的危险性高8.5倍。因此，急性情感爆发的危险是存在的。数据还显示，焦虑发作也可以更容易引发心脏病。“强烈的愤怒或焦虑增加的风险很可能是由于增加心率，血压，紧缩血管并增加凝血，” 研究小组Tofler教授说。

      Tofler教授表示：“我们的研究结果强调有必要考虑在突然愤怒的时候保护个人健康。潜在的预防方法包括减轻压力的训练，以减少愤怒，或者直接避免愤怒对峙或相关活动引发强烈的不安。” 此外，通过减少其他危险因素，如高血压，高血脂或吸烟也能减低风险，提高总体健康。

      这项研究也提示，当医生在治疗有心脏疾病的病人或者需要预防心脏疾病的人的时候，个体的愤怒和焦虑的频率也应该进行评估。

DOI：10.1177 / 2048872615568969

Triggering of acute coronary occlusion by episodes of anger
Thomas Buckley, Soon Y Soo Hoo,Judith Fethney,Elizabeth Shaw,Peter S Hanson,Geoffrey H Tofler
Abstract
Aims: The aim of this study was to report the association between episodes of anger and acute myocardial infarction (MI) in patients with angiographically confirmed coronary occlusion.
Methods and results: 313 participants with acute coronary occlusion (Thrombolysis In Myocardial Infarction 0 or 1 at emergency angiography) reported frequency of anger episodes in the 48 h prior to MI. In primary analysis, anger exposures within 2 h and 2–4 h prior to symptom onset were compared with subjects’ own usual yearly exposure to anger using case-crossover methodology. Anger level ≥5 (on an anger scale of 1–7) was reported by seven (2.2%) participants within 2 h of MI. Compared with usual frequency, the relative risk of onset of MI symptoms occurring within 2 h of anger level ≥5 (defined as very angry) was 8.5 (95% confidence interval 4.1–17.6). Anger level <5 was not associated with onset of MI symptoms. Compared with 24–26 h pre MI, anxiety scores >75th percentile on State–Trait Personality Inventory were associated with a relative risk of 2.0 (95% confidence interval 1.1–3.8) and in those above the 90th percentile, the relative risk of MI symptom onset was 9.5 (95% confidence interval 2.2–40.8).
Conclusion: Findings confirm that episodes of intense anger, defined as being ‘very angry, body tense, clenching fists or teeth’ (within 2 h) are associated with increased relative risk for acute coronary occlusion. Additionally, increased anxiety was associated with coronary occlusion. Further study, including the role of potential modifiers, may provide insight into prevention of MI during acute emotional episodes.