Review. Stem Cell, 2010,28:885-893. Abstract: The human OCT4 gene can generate at least three transcripts (OCT4A, OCT4B, and OCT4B1) and four protein isoforms (OCT4A, OCT4B-190, OCT4B-265, and OCT4B-164) by alternative splicing and alternative translation initiation. OCT4A is a transcription ...
Summary: 1. HIV is a serious but manageable chronic disease that affects persons of reproductive age, many of who express a desire for biologic parenthood. 2. Current treatment of HIV can limit the risk of viral transmission to partner and offspring. Recent studies show that in HIV0infected women, ...
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