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本帖最后由 saturn 于 2010-5-12 00:23 编辑
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for your first question, i think the usual sentence might be epigenetic regulation of gene expression ……， i don't think you have seen the epigenetic mechanism of DNA methylation, histone modification or non-coding RNA in the regulation of ……， such kinds of sentences.
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0 j3 |2 {1 u, x. O3 ffor the second question, one paper is published by Yijun Qi in NIBS- n Q& V, d, }; V
DNA Methylation Mediated by a MicroRNA Pathway.. z# w, \, B$ b6 ~% R g
Wu L, Zhou H, Zhang Q, Zhang J, Ni F, Liu C, Qi Y.0 ~ G5 r6 I, U2 E0 p1 Z
Mol Cell. 2010 Apr 7. [Epub ahead of print]
4 h0 ]8 T$ Z& N1 C+ ranother paper is published in cell R: Q0 G- `( F6 c% W/ P
Transcriptional control of gene expression by microRNAs.
- e, j1 p% i: X U) Y4 l" IKhraiwesh B, Arif MA, Seumel GI, Ossowski S, Weigel D, Reski R, Frank W.+ A2 R( F4 m- s3 g" C
Cell. 2010 Jan 8;140(1):111-22. T% Q ~9 P" A4 x- K8 |+ y
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although you might argue that these two papers are only in plants, i think miRNA should play a conserved role in evolution. by the way, there are also some other similar papers, you could find them in pubmed yourself.: ?5 ]0 ^( f0 N" L9 f7 l
" e. P0 ]+ a4 l$ @personally i think there will be nobody agree with the narrow definition you listed before, RNAi should be involved in epigenetic, and it plays a role in PTGS.
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have fun in epigenetic field! |
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发表于 2010-5-3 08:08
发表于 2010-5-7 00:29
