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肝细胞 hepatocytes w) I6 z2 a! l5 \
1 Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010). 3 R7 h" b6 s9 b4 ^7 N" f! v2 }
2 Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010). : Y, E! Z3 p6 z* o+ r% a
3 Sullivan, G.J. et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 51, 329-335 (2010).
! ^- N5 j: o/ G1 S4 Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells. Hepatology 51, 297-305 (2010).
4 G$ p) h" ~8 z8 i- C3 T7 Z6 L; K5 Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 19, 1233-1242 (2009).
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神经细胞
) {8 c) Y+ i% n. w4 g% Tneural crest precusors
+ l# ]; f) j2 |* u* Y' D2 ]6 Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009).
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! f3 X3 ^3 r, ~' ?0 S4 h0 }3 @5 jneuroepithelial cell$ a+ t& p; b0 ]6 [
7 Hu, B.-Y. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences 107, 4335-4340 (2010) , v" ?! m4 o/ \5 @% Q
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motor neurons【包括文献7】" m! b" l# t% c. k! k
8 Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).
6 _$ G. }: @, K# D+ v9 Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009).
) F) [$ Z+ w9 G. E t+ B0 H n& q10 Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotech 27, 275-280 (2009). / J9 l, t8 }7 j J
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dopaminergic neurons of the midbrain 【包括文献10】
) N" n0 @. ]- ?; k+ I. i11 Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009). . G: _4 S' ? U5 i! C0 P. t
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Retinal Pigmented Epithelium, ]2 v4 W: z# p; d* S' ?
12 Buchholz, D.E. et al. Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells. Stem Cells 27, 2427-2434 (2009).
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retinal cells
: [' O% k O n+ g13 Osakada, F. et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122, 3169-3179 (2009).
6 V T+ b1 Z; M9 i( ?4 M14 Meyer, J.S. et al. Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proceedings of the National Academy of Sciences 106, 16698-16703 (2009).
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心肌细胞 cardiomyocytes0 u1 J5 ?, k: d
15 Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).
1 b7 ]# E+ t' a# T16 Carvajal-Vergara, X. et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465, 808-812 (2010).2 a* ]6 E% n. }7 e g% [" V; a& B& f
17 Zhang, J. et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circ Res 104, e30-41 (2009).7 ?. C4 k% K. T0 Z+ x
18 Zwi, L. et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation 120, 1513-1523 (2009).
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; V% U7 U$ |- }, ?血管和血液相关细胞
: I. D2 m# T7 j8 T5 whaematopoietic progenitors
( k% Y6 w$ s. h! H3 `. d8 D2 q, Z. }19 Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).2 Q- {# {+ V; X; x, w# K
20 Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).) C, O& F' P9 F5 \( Q( A
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blood cells
7 v4 v0 Y' L7 d) h3 q21 Choi, K.-D. et al. Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells. Stem Cells 27, 559-567 (2009).$ ]" H5 r/ Q$ W* h0 Q/ p+ t
" ~- Y R) [; ~) ]8 q+ O- xvascular endothelial cells【包括文献21】
! R3 `! V4 x4 S8 D: S4 O4 m22 Feng, Q. et al. Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence. Stem Cells 28, 704-712 (2010).6 C( T* h- t* K2 t. n. W: L
23 Taura, D. et al. Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells--Brief Report. Arterioscler Thromb Vasc Biol 29, 1100-1103 (2009).0 v# [3 x# r: \' I" B0 a1 U( g& P
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胰岛素产生细胞 insulin-producing cells
+ h! ?( I7 l! I( B$ u24 Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).
. `8 Z! F& }4 ?1 h) D3 \25 Zhang, D. et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 19, 429-438 (2009).
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26 Park, T.S. et al. Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells 27, 783-795 (2009).
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{' H8 b; y. }; \7 R" [脂肪细胞 adipocyte
1 v% u, g6 O/ h( Z27 Taura, D. et al. Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters 583, 1029-1033 (2009).4 D8 E) I: m/ T X0 \4 r
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Y4 d1 j3 A' A- R: m8 q可能会有失误的地方,见谅!
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