干细胞之家 - 中国干细胞行业门户第一站

标题: 老狼的个人空间记录 [打印本页]

作者: sunsong7    时间: 2019-1-8 21:46     标题: 老狼的个人空间记录

"genetic mutation" should be exactly as "gene self-editing"2 w# w6 H* o  n' l0 [! d
2017-12-1 13:17
) j- }; w) T8 S8 q$ ~: R: g, m( VBioreactor in vivo would be the terminator of illness.
( B( P( ?( `! {7 w& `! X2017-11-20 23:09
# T9 q" G' ~& c$ drenew tech:剔除衰老(病变)细胞占位可以恢复青春。- b4 a+ n+ [6 _/ F3 E7 ~
2017-10-23 12:50% j+ a+ X+ }2 N! {% |
魔不疯,鬼不魅; 道非盗,仙非妖;神无形,兽无极。
9 q/ _5 t5 d/ Q9 P  j( \: B( B6 E2017-9-30 10:58
* c: T; ]! T; i. q1 r+ F, KLife 3.0——from decoding and coding to reading and writing: P! g7 X& p8 X# d. @0 _
2017-9-21 22:32
# ]+ M- v% Q! x8 F8 C理论创新:亮明立场——先颠覆,再完善6 e8 w0 H& o% `( y
2017-2-7 00:07
* R& }" L7 L; o" d. w. h干细胞第二定律:与细胞外基质共同构成多潜能;
+ M4 S4 }' `: Y# [2017-1-3 11:14
! d4 W1 ?# `0 p0 T$ h8 T干细胞第一定律:全生命周期保持增殖分化能力;
% {8 W9 q/ D- v  `( b( Y( q2017-1-3 11:13* D! _% z5 A. |% ]! w2 Z
NgAgo——Never give A guideline operated!/ a$ E$ i- g8 q8 ]9 j5 Q3 @  o
2016-12-1 10:099 w& V; J7 H8 f/ ~: V' W# D8 C
表观遗传—— 一切皆可改变  一切皆有可能" j* |- K4 v- [+ U( A0 O% s" X% _
2016-8-17 23:37) Y5 U9 |# C8 }# J+ \
子曰:吸血鬼疗法——养儿防病 养孙防老1 f* A. m* p0 M! j) G  ?. S4 x/ ]
2016-5-23 12:050 D9 d  A! |& R, b# q1 r
NgAgo——Debug tool kit for mammal cells& m% f+ ~  J" c  m
2016-5-9 13:094 ]8 f  o5 Y: Y9 e( l
公理之外 皆需证明; 科学命题 皆可证伪。. B# r0 }6 ~; O3 S' V; N- w) I
2016-1-2 00:20! _0 d: K% W$ s; j) V
低氧——破坏线粒体功能、诱发炎症、导致基因突变! O# e. z& M8 v( Y# Q8 c2 ^
2015-12-16 20:19. v' y8 D" N8 m
癌症——炎症部位组织再生过程中细胞去分化失控形成的幼稚化新生物。% X# p3 D) E4 L1 `
hcoohboy: 一个有趣的假设~但是没有炎症就一定没有癌症吗? (12-18 16:16)
6 m2 t; j" w( }6 h- Nsunsong7: 炎症与癌症同在,Hanahan D, Weinberg R A. Hallmarks of cancer: the next generation[J]. cell, 2011, 144(5): 646-674. (12-19 19:45)" ?" \, K, c. g4 D, c  E
hcoohboy: 3ks~ (12-24 16:45)
4 J2 [/ S. n6 E0 }2015-11-18 15:54$ V" W! D  ^1 s( A6 L6 {/ D, s
抽象世界与客观世界的真理判别标准是不同的: 在虚拟数学世界里,逻辑是一切命题的唯一审判标准; 在客观物质世界里,证伪是一切定律的最终审判依据。
; U" C& t% ^; b: d2015-5-20 14:13
5 f, L+ z" U7 t2 E7 Q+ k7 } 传统生物学将死:进化论=自然神论   基因轮=宿命论   细胞论=活力论翻版。    现代生物学曙光乍现:系统生物学=数学 结构生物学=物理学 合成生物学=工程学
+ e3 N) r2 Y! W/ xhelong: 系统生物学是把细胞、基因、进化、物理学、信息学(数学)、工程学等都打包起来的所谓新学科,目前只做到了简单组合,还没有达到系统集成阶段。合成学更多偏向于化学。 (4-21 19:28)
2 Q8 d9 y  s# P6 e1 Vsunsong7: 方向对头,努力总会有结果的 (4-21 20:05)# ]" E* I5 e6 N# ?' {* z* x
2015-4-21 16:46! S1 \% A' {& G3 {# K; T  G" p
search and research is just disassembling the creature.. [0 E% y+ |( |9 K3 \+ F* l
2015-4-7 17:01" I' C6 L1 b+ v8 x
selection is  the act of intelligence: x4 Q5 p+ f( d# E8 d! \
2015-4-7 13:49) ?: I9 t/ P; s
Genome fusion create neoplasm
* r$ O' o! G3 I  X+ ~. C7 G2015-1-20 13:105 D8 P/ {) ?  B3 n4 L& {% M6 r
STAP——Stupid Trick  Against Professional " o7 {' j  N' u1 T- w# X
2015-1-1 19:292 y. g0 K+ i' q; W2 d
information=structure=negentropy
* ~# f, Q4 `2 J! |7 e% K9 Q2014-7-22 17:36
0 |' n# n. o5 x. U/ ^Natural mutation does not result in new functional genes 
+ h9 ^8 O/ I; L! S2014-7-3 14:06
- m% B- S+ l+ J, J9 Jlife is wisdom creation instead of natural evolution2 o* a8 ?6 t( \' ^- T5 f
2014-3-27 09:33
! y! l; j  ~+ k  C" vlet us explore the source code of life !
9 S' d8 J  ^% l& J9 C+ ~2014-3-11 13:11
8 {9 g% c  A, U# z: n% \; Ybio-manufacturing——processing,machining,casting,printing,3D prototyping,duplicating,cloning,life replicating.) S5 Z  z$ p' s! j- e* w
2013-10-7 23:06
+ T; ]- K2 ]' A4 z, oinduced abortion would give the key for curing cancer ) d' U4 f3 p0 l" H! g7 d( P
2013-10-2 23:33
) j" v# \4 D0 t' B: P“key breakthrough” in molecular biology are entertainments+ v9 k, I! k8 u! `
2013-6-16 11:50
) r- p9 K$ }& x7 W6 r2 rRules Of Living:trial-and-error exploring,survival takes the legitimacy0 Q/ v3 \7 {0 u9 Z. R6 u
2013-6-16 11:27
' o! P7 r0 q* PLife is a set of debuging programs
; V% S2 ]; X7 t2 i+ {2013-6-15 18:40( _" r) p! h' J
current biology is closed,destined and agnostic,it is  the only contribution is to kill cells
, F. N. q* H( |3 U4 S2013-5-2 08:54
5 N" v2 s2 _! K, h( @' Linformation,energy and construction are the new base stone of biology,instead of evolution,gene and  cell  tales
' S% j6 }( Z; i1 D8 v2013-5-2 00:51
5 h* j# P0 \9 {* {* l  q8 e, ^virus is the messager of  the universal life network
; `& {2 w7 j' f* c2 f2013-4-18 14:33- N; \- ?( z2 l. B3 n4 x
Genetic information doesn't improve cancer risk prediction5 L/ ~3 B1 ?/ W* P
2013-4-1 09:20. w, c' `8 f( `8 O
There is no early diagnosis of cancer,but early prevention of it
" E. w- L8 z% T' y  A3 X2013-3-27 09:173 M: Z8 t/ |* ]+ f) |6 K
hypoxia maintains stemness or carcinogenicity
! k' F- x5 Y+ D0 A, c; i5 `6 ~& U+ L. M2013-1-2 05:21
% n0 R0 I- A. @2 |cancer is the living fossil records on origin and evolution of human being$ w8 `3 [7 {; n# u7 [
2012-12-9 23:31  @4 p9 q' h  A5 L
information island results cancer: }- P0 y9 G+ E4 W0 s
2012-12-9 05:23
( S4 _. _2 |  B; s0 clife is digital game
- P% Z$ ]6 I: w- i: f& z1 \2012-11-10 00:17
: G1 y3 f  ?6 `& i; L: \cancer ——severe abstinence reaction of cells to niche addiction
8 m9 Y9 t* w) R2012-9-28 12:11/ \, o0 F( R" w2 C" l
未来生物学终将回归物理(熵)及数学(分形)的美感1 W" s' ]; X5 Q
biomater: 熵理论适用于任务物质。。。。也适合于生命 (9-26 09:28)0 v' B. Q: R, j2 {2 @
2012-9-25 21:22
- K; {( e4 H. mmembrane holds the key to life1 |3 r' Z; x8 w5 x
2012-8-19 20:24+ j  g1 F/ a1 M$ q  d2 j
Cancer is the default state of cells
2 h7 F! j* k$ X2012-6-26 22:17
8 ~: h! C$ ~& j: j$ Cmainstream cancer theories could be overthrown!
$ O9 q2 Q5 Z0 u% t2012-6-25 15:43
( J0 D% f+ o+ F0 e, S) qcarcinogenesis has nothing to do with the gene mutations but is  the result of niche reprogramming...
- g# j! p1 X6 b& D# A* G2012-6-7 09:36$ I- u9 _. e. [; P: s& n+ t
every living organism connected with the water, one cell one world
9 I) `1 |: K# C- e2012-4-19 22:065 s8 P* o- Q* X7 a  N1 r$ i7 L
chemical structure of cancer cell determines it's biological function...
. T9 n5 T7 y0 K) C3 a2012-4-7 17:56) c( w0 p* [0 `8 d7 ?7 v
Mann tracht und Gott lacht
& L. g* b. Y5 Y- g8 @; {2012-3-24 21:34& B8 P# S3 a% j/ f1 P( N
Darwinism or genetic determinism is a fairy tale!
. C: Q$ x( H/ A# z' X& Q2012-3-13 15:18
. |: [: R) r/ wniche isolation is essential for cancer speciation
/ t$ i4 o3 Q9 ?/ g  d2012-3-12 12:07( B2 U* l8 }) Y5 e( t2 C
Hybridization Creates New Species,Mutation results species extinction8 w# w0 }/ l" Y2 Y6 P
2012-3-11 18:21
! Q& G7 T8 x. \4 z6 K; P. T2 SROCK may join the niche reprogramming...
4 L( Q& k: N6 i' G1 W6 N, tyuhaoze: 这是篇文献吗? (3-9 10:41). j4 j4 Z+ V9 [$ |! h! G
sunsong7: http://www.stemcell8.cn/home-space-uid-6268-do-blog-id-1211.html 突破:病人体细胞及肿瘤细胞长期体外培养(附原文) http://www.stemcell8.cn/thread-51419-1-1.html (3-9 10:46)+ N4 I1 P! x, z3 h. a% b
yuhaoze: 啊, 我看过这篇,还顶了呢,谢谢哈 (3-9 14:37)
( M6 Q2 T0 \2 t- o9 ?( q) a2012-1-19 10:527 b' `2 l; ]( E6 F$ j: |; a
oncogenes are pseudoscience+ C$ a) P) W' i9 n3 Q) M8 A
2011-12-29 13:55
- W  O. \* j  T' pgene mutation leads to variation or extinction, not new species
/ u+ c. k& p6 Z" [' x4 O6 p2 G2011-12-29 13:286 u# b- B/ f$ Y: Q( D5 w+ x; |0 g
oncogenesis is non-Darwinian event. d- O! q1 y( u$ T' S
2011-12-28 22:56
2 B+ I9 S$ @  F  ^; bdisorganization activate neurogenesis activate oncogenesis   " X7 ^/ \  T$ y2 A
2011-12-22 23:38
1 s7 P6 v0 [8 V2 h) SMSC is cell feeder,tissue scaffold,immune firewall and biological glue
' n+ @# ]: ~1 ?# x# B2011-12-19 19:46
9 z1 u- F$ R# X1 }' A9 _! w' ?cancer is Noah's Ark(species carrier and life explorer)
6 W$ K" h2 u: G6 |8 \( a2011-12-10 09:46
0 x( x# X& |! ^( Tcell fusion create new species, gene mutation induce variation+ k# M* O- B1 O) \* D5 s/ }- e7 N6 r
2011-12-10 09:36
# y0 |; A3 R# ?, [GVT will be cancer terminator, Cytokine storm will be cancer preventor
& G* e" J- v5 y" \( `6 t, C2011-12-8 12:560 |0 O! X5 d& y) [3 d, f% \0 K9 x
cell fusion results regeneration,reprogramming,neogenesis,atavism; cell division results differentiation,apoptosis,senescense,development;/ w% A! {$ |3 F9 e
2011-11-27 14:54$ L, h8 f: N, y& b
Cancer is between protozoa and mesozoa, not metazoa...
- ^5 T& ?% d* o" A2011-11-27 00:25+ G# k" E& a8 W  j6 Q( {$ S# t  f/ I) V
cancer is neurological disease! haha,I got it!. w/ {1 @, g0 j+ Q. H! s7 H6 x
2011-11-22 22:06; _; \) k: }" z9 D0 T: y
you are cancer,fetus is tumor. 佛曰:汝既是癌 癌胚如来
7 [- K' f8 [. G" e7 g2011-11-12 11:27& `- q, c. j3 g1 Q4 h4 Q% e$ H, W
cancer is the ecological invasion of hacker...
& j# ]9 R) f: j# H& T2 t2011-10-5 10:31
" Q- a. u$ K2 m: R6 _+ mmicroRNA is  negentropy?
3 {. r8 _5 a9 d  D+ }5 V% l$ x2011-9-24 00:48
( `$ ^$ x1 H- A6 {- ]3 ^cancer is the social problem$ [3 x# g# L# f3 c  [  |
2011-9-9 23:33
5 e; x7 J3 e; X8 l5 V7 N6 _  b* z  k1 WScience is the games of nobleman or madman# n( d2 h; R# M7 u
2011-9-2 15:03; @+ i  O$ o4 W/ [0 `7 E
cancer resulted from disturbance of biological liquid crystalline state of ECM. c0 ^' u6 N6 W( @9 v0 }: z5 k
2011-9-1 20:13
8 Z  o/ i' {7 Qniche n-dimensions——space, time, momentum and entropy; energy, material and information flows; physical, chemical and biological factors;topological, thermal, and fractal influences...
/ D4 H4 v: Q4 W' z) Y  x$ c2011-8-13 00:37: w$ m5 g/ t6 w; B- e
Second recession is coming?1 e' n' a) G' C7 W* K8 `8 H" |% l
2011-8-9 23:58
$ _2 k, E- c/ B( Ecancer may be from sexual reproduction of somatic cells.0 n" h. L4 O* [; G' |
2011-8-7 00:16
5 w) w9 k1 f$ z, e& swho determine gene? genetic determinism is fatalism!
& w; C' @4 S' L7 ^3 M( s2011-7-30 11:26
9 s- R9 W2 I% e* T0 x* Aniche reprogrammabllity is the key of solving cancer problems...5 a: ]* K" @# \' L0 |  j8 |
songtianlong: i can't agree more!!!O(∩_∩)O~ (8-14 20:42)7 ^3 Z! ?5 h  L8 T, M
sunsong7: hehe. thanks for interested in this topic, welcome future discussing (8-14 20:54)
" S+ O. w" G' P  ~) M) s* V2011-7-24 01:24
1 R2 y9 H; ~2 E% }) T) t* Pcancer results from acquired genetics alterations.4 `1 b( Z3 n' N5 c! a1 Z6 O
2011-7-20 21:37
" H+ t" u( M! @8 P* X, LCSCs are the low differentiated cancer cells in G0
2 H1 `( h+ S; W/ b: c5 y2011-6-29 16:30
" v8 k+ a& N5 ]iPS future——in vivo direct reprogramming .../ {; v2 A8 O- L2 I: q3 j% S
2011-5-31 15:20
+ X7 M4 I3 S: h5 s% I. z# u- R4 wniche reprogramming——cell fate will be manipulated by cytoplasm - microenvironment interaction http://www.stemcell8.cn/thread-40755-1-1.html/ i! D2 D/ v6 _* H
2011-5-31 01:28
" E! Z# S8 z; W$ Qall the somatic cells of Mammals are totipotent !
- C1 _- D; u) }  L" s( m2011-5-22 22:22
# S" [/ F- |. k; u, H. j% zmiRNA——The manipulator of  cell fate!: P8 d5 Z% M; b) F+ w* `
2011-5-20 20:21
& F0 f# {+ w0 m/ Z《Cell Stem Cell》means “cell is stem cell”   活细胞就是干细胞?
9 a4 x: e9 T# |% N' o2011-5-17 12:38/ @8 U" |( h4 I+ D
cancer —— good nuclear in bad cytoplasm!RNAs are cytoplasmic determinants determine  cytoplasm determine cell fate! division is differentiation is cancerous is life !
6 T- W( |( `/ l6 w- p1 q& ~' J" E8 t# H2011-5-11 12:31
' z7 T$ ~! Q5 ?5 Q/ i/ @8 }cancer results from cell dedifferentiation...
8 _, Z! ]1 W4 N$ w! o9 O' x2011-4-28 18:07/ @7 S$ \) r0 m. c% I
differentiation——asymmetric cell division !
3 U& W8 r5 t. s7 X4 V% K0 {! y2011-4-28 18:047 Z/ Z9 B* N: I, l0 n/ s
cancer origins from the regenerative cells!. {/ P( \4 g5 T9 M5 V: s
2011-4-28 17:52( b8 ?" m) R; S3 x; H; F
Proliferation is differentiation potentiality!
* j/ k% d% }! K& ?- [/ @  U1 K  x$ I2011-4-28 17:49
; z/ e# ?  h' j2 v- }) xiPS——the key of Pandora box!
: T8 {0 H7 n: U# I2011-4-27 22:36. E/ C1 n  t* m% X
Aristotle— "The whole is greater than the sum of its parts."
+ E2 H2 ~2 }0 e( `1 M8 e2 E2011-4-27 00:20
0 d- ~; j' }( Z1 kcancer——atavistic cells
& {3 |+ {, x0 L/ `' Y8 W" W# ]2011-4-20 00:20
3 t! x) h8 k0 T! Tcancer——cellular atavism!1 r0 X1 G. W6 a# s
2011-4-20 00:18  k( L$ h- U& i5 I' `! M' K" E
cancer——evolutionary ancestors of mammals.* m6 V( C0 m) d  v- Q; v" r! L
2011-4-20 00:092 N4 j# `4 y5 {, a
肿瘤是细胞自组织缺陷的产物 
: L  ~: T8 W6 K  Y: d! a0 i# I2011-4-17 01:41
* r$ s$ I* j/ Zcancer——Metazoa 1.0" ^; P' u. Y/ I3 g% r
2011-4-17 01:00% S$ R/ @4 A2 x- u
US——the Axis of Evil!
. b( o, d, B' |8 B. \+ z3 H, c2011-4-4 01:195 v4 C9 l* _; f8 j5 [0 s
美国是世界的邪恶轴心!
8 ?) ?* ]% j5 S4 i4 tsunsong7: 沁园春.血               ---作者:萨达姆   日 本 风 光, 千 里 地 震, 万 里 海 啸。 望 仙 台 内 外, 废 墟 莽 莽; 东 京 上 下, 顿 时 逃 逃。 核 站 爆 炸, 世 界 惊 涛, 地 震 海 啸 试 比 高 ... (3-22 21:25)7 h" S& G5 R& H/ P' w
2011-3-22 19:06
1 k+ A+ M6 q+ p6 H) r  }$ S. Xteratoma is derived from endogenous iPS!
$ u, C: J& N" n! {* G' X5 v; o1 D2011-3-15 21:44
6 ~. z  I. R+ b$ u3 D* Fips is a luxury gambol on  
. i+ \( ~- q# L* R2011-3-3 14:506 i, a+ Z, _. i9 @3 v
cancer is intermediate of species evolution/ i  }4 p2 u& n; F9 D. d
2011-2-12 12:29
2 ^( B. b2 w; n6 m) T* Estem cell now is on the eve of coming medical revolution* v  p2 A6 z7 k4 |
2011-2-12 11:20
# ^% t6 u, B# E$ ]Inflamation is the reprogramming process of somatic cell in vivo!: {5 x) O2 ]# U$ Y/ V5 k5 }
2011-1-31 14:49) N1 U2 V; ^1 F( A8 R/ B) S% `- C$ D
so-called medicine is niche regulator!& t6 {8 v! ]( {  ?4 i' W0 u
2011-1-23 21:45
$ x7 |! y9 |+ u6 X8 f1 Jendogenous iPS is the cancer initiating cell!" |& E9 H5 f+ z; B, t8 Q! Q- @
2011-1-17 16:47+ r2 M8 J1 e% R: Y# {3 l  M
cancer is unicellular organisms!
6 V$ U6 {% y0 p" a$ n2011-1-9 22:04
( W: m8 r: O/ qPandorabox Has Been Opened
0 L0 h+ }1 v" L2 u& K0 |! E4 X3 s  R2011-1-7 23:24
5 ]( a# ~! Y- ]3 A8 j# \+ c/ w1 diPS is the Emperor's New Suit ! - P7 ~7 g$ h; ?- N( Q( ?
2011-1-5 23:50( p* n' H0 o9 K1 y7 }, a# _) n
cell-free is the final solution of stem cell therapy
) w; l) D7 y: N1 b1 T0 O8 A5 n2011-1-5 21:46/ c! n# B$ V7 n, I% `
niche is telling the story of stem cell...
+ Q7 {, H. }  ]: a+ G. `( Q8 L# q2010-12-29 17:32
7 T0 Y8 s4 K( Z+ d7 r0 }3 K" }cancer results from reprogramming of somatic cells/ I7 Q2 d" p( D- y1 X4 x
2010-12-25 18:56
1 M1 R; F0 k* ]5 F" W3 a& Scancer——good cells in bad niche!; d4 o9 k5 b" O4 Q& p) P+ R
2010-12-25 16:02
& h2 r( z# e" @" C* m) c" J) U, A/ acancer无罪——制造产生罪犯的土壤才是真正的犯罪!
1 r9 X! Q# c1 `; i4 d/ P% Xderon: 灰常同意,有相关文献么? (12-19 09:41): J% c! A3 f* G' V0 E6 z% v
sunsong7: 呵呵,请来参加讨论——癌细胞的发生可能是一种“返祖”现象? http://www.stemcell8.cn/thread-32073-1-1.html (12-19 11:33)
( G  V  ]4 y) w* t. Rsunsong7: 问题讨论 http://www.stemcell8.cn/forum-re ... 709-pid-246202.html (12-19 13:29)- c6 G& H, e" w: T; K( E7 p
2010-12-18 15:54
; p% C. o; o& M# N' o! Y. Z子曰:上善若水 大成若缺——干细胞治疗的终极解决方案将是不移植外源干细胞!
$ J$ A9 G. O5 H- n2010-12-15 15:07
6 V1 D+ R* |+ p; E老狼的记忆——大洪水
" k& I; M1 E: n$ G0 a: F2010-12-13 23:25
# ]3 Z1 ]$ g- A; U& Vcan cancer randomly differentiate into norml cell in vivo  
( c  L& s, J, b0 _2010-12-13 22:33! Y0 b, u- z/ X+ U
omnis cellula e cellula# z' \& _# R+ |  G' q; k1 O* w3 q
2010-12-12 09:28
! j2 r8 C6 ^" {$ G9 `- tStem Cell ——The Origin of Disease
# m+ T3 ?9 y. |) C( j2010-12-12 09:27
# q" r6 b9 Z7 w+ u3 h% |
作者: sun_happone    时间: 2019-1-9 16:31

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