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求助文献;; T+ _! d0 ^: g8 q/ \5 B+ e
) ^. K7 Y$ e! G5 {1. The epigenetic landscape of T cell exhaustion. Z& Q" l4 _- J2 @
https://www.ncbi.nlm.nih.gov/pubmed/27789799/. n; M3 I& ~3 L8 E& J7 I; ~9 I
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2. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade9 g: h4 d; N+ A% G5 B. T1 Q
http://science.sciencemag.org/content/early/2016/10/26/science.aaf2807
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3. Can T cells be too exhausted to fight back?0 T# s) H5 n0 R! ]4 J* l
http://science.sciencemag.org/content/354/6316/1104) q( b' o' |% T/ z. ^7 G& Y
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