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求助文献;3 {# h: N/ K7 ? |* V
0 I, l: n, R9 Y6 H% d+ ]1. The epigenetic landscape of T cell exhaustion.& ^- F6 Z/ A. t: F
https://www.ncbi.nlm.nih.gov/pubmed/27789799/
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2. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade% D _' @% L `1 ~7 w1 n/ ]
http://science.sciencemag.org/content/early/2016/10/26/science.aaf2807
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4 O: T$ W; N4 D' { _$ D6 Z ]3. Can T cells be too exhausted to fight back?
* o5 z9 E- V6 N$ Jhttp://science.sciencemag.org/content/354/6316/11041 Q1 I1 a; o7 S; Y# V' s
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