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- 积分
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- 威望
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可是这个版本（如果是，我就给你下）：- ]8 y! b4 T6 E/ ?+ { Q& y
Table of Contents
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I. Principles of Developmental Biology5 @- {/ e8 T+ e; z3 ?
$ x/ }% q9 Y3 U+ v
1. Developmental biology: The anatomical tradition
5 G; F0 g4 E- Q7 _8 B8 V- v- |New techniques of mathematical modeling of development
" G' l0 I$ H" b3 e- o4 C1 E4 b2. Life cycles and the evolution of developmental patterns* S1 K+ S- p( p8 K8 Y
Recent advances in planarian regeneration( x) O9 d3 r. m
3. Principles of experimental embryology
% \/ ]0 b7 z7 a1 r, r2 C( w4. The genetic core of development- q; v" P6 h! P! \: A" J
5. The paradigm of differential gene expression
/ L' i$ [3 b; u" E( I, z6 b3 @4 KHistone modifications
2 Q) h; m. \+ v* PMicroRNAs, K8 I- X5 j* E5 h: e9 k
Pioneer transcription factors
/ n2 g/ _" k$ ]Mammalian cloning and methylation patterns
6 @7 u3 D/ N+ H6. Cell–cell communication in development
+ P0 J2 J/ ~* g) s+ u RStem cell specification and stem cell niches
, c. ?" Y0 ]* n/ }Morphogenetic regulation by cadherins& E- E# p+ `0 G& }" ^$ B2 v
Noncanonical Wnt pathways& M. M0 V3 ]0 u
Dependence receptors and apoptosis7 H0 c; A7 i+ C, I* c
Community effect and autocrine factors( `5 r2 q% d) h; Q3 c+ m
$ r U, |3 {+ w5 T' Y' h* UII. Early Embryonic Development; ~7 u3 t7 z8 m1 o+ s& j& j
8 o) [( w: g( K4 P0 L8 }; k
7. Fertilization: Beginning a new organism2 ~2 s9 W6 b. a( P' \6 T
Cortical granule components! T' l% U9 |* k& J- f) f
New mammalian sperm–egg binding model
/ i+ ^4 p v' c9 D1 o' V' }Mammalian sperm chemotaxis and thermotaxis
' y! t3 C) T* M/ T% `: }# W8 {; jMechanisms of sea urchin sperm chemotaxis
9 i7 }3 p Z4 Z, ?5 C( W9 A' sSea urchin bindin receptor6 c% E+ u+ A" f0 [6 b* J5 W5 p
Oocyte translation inhibitors and their removal
) f" o* D% c" y, V/ `- v: E+ b( `New hypotheses of sperm activation
" R7 P- G$ b/ I! d# [- y9 Q+ aMammalian sperm–egg fusion, j) R' z! N5 {# n4 y+ A H9 Z
8. Early development in selected invertebrates
l5 }- l T1 MWnt and Nodal in sea urchin axis specification" v. }3 t( o4 H6 Q- F
Coiling genetics of snail embryos
+ G" k6 H8 V* tFunctions of tunicate yellow crescent6 ~. J9 g5 Y1 r( A: R
Roles of FGFs in tunicate development7 S7 K% m8 _* ~; i: A4 |
Tunicate heart development
3 h; t5 N+ d5 E5 {; t2 [& [9. The genetics of axis specification in Drosophila
# Z( Z+ f4 @8 \" fFGF signals and Drosophila mesoderm formation+ ~% t# F( ]3 J
Transport of Nanos and Bicoid messages to opposite ends of the fly oocyte
: J8 P; [5 P5 S- ENew model for gap protein stabilization
( H7 b+ W/ y- U& w7 @10. Early development and axis formation in amphibians
0 e( `" P& B) P# k: r+ H! n7 ^New models for organizer formation in Xenopus
1 X. U# T6 O; s7 [New model for mesoderm specification in Xenopus1 C' Y% F" |$ n( R7 O2 ]% |
11. The early development of vertebrates: Fish, birds, and mammals y- p! E9 P& d/ [# G6 k6 C
Maternal effect mutations in zebrafish
' k6 Q; c: ]. w; u" yNeurulation in zebrafish' D, y/ G( R2 O a* r* V
Retinoic acid in anterior–posterior axis specification in chordates( T6 J! K) O1 F- ?# H. e
Ciliary movements and left–right axis specification in vertebrates
4 N3 F) j, ~9 w, Y, y8 k" jRole of Cerberus in chick head formation
' O/ I% D" M4 T4 C1 UMesoderm specification and migration in chick gastrulae0 m, ?; U5 [- q7 o7 {6 u4 R1 T
FGF and cell fate in chick and mammalian epiblasts" v6 k" z- U# }, v* \
Induction of pluripotency in mammalian inner cell mass blastomeres
" S. D3 m7 m5 Q2 @* W6 `4 iHomeotic transformation in mammals due to total Hox paralog knockouts
9 M6 b5 U( L' Q9 NControversy over blastocyst polarity in mammals
* A+ L, [! @1 J9 L/ S# IFolate receptors and teratogens affecting neurulation! l9 F1 G( q" O2 V0 P9 ?9 {
5 I8 f8 \* D- M+ D( J0 `, OIII. Later Embryonic Development7 k `/ |0 [9 L6 `9 [
& p! P, b9 D& E9 x- `' d7 j12. The emergence of the ectoderm: Central nervous system and epidermis
' V+ Z1 d j4 s) x# N$ J- SGenes specifying neural fate/ x! _+ d% N. ?: Y: x
Human-specific genes specifying brain growth
& _# W: x! |- \$ p! f$ @' Y" ?$ M& Z& KProgressive myelination of the human brain
! \+ x7 t& ~. KNeural stem cells
0 ~$ j& S' h$ j4 Y2 N3 }$ M9 oEye development and blind cave salamanders
. U, t4 c& M8 x8 t- }4 W) BSkin, hair, and pigment stem cells
$ e- X: M0 n* ^) w) U6 t- H! f+ w13. Neural crest cells and axonal specificity( ?4 {4 j9 a9 {7 g& t$ R) D$ a, B
Neural crest cell specification and migrations
( M9 a' S% c% [# h, zHead vs. trunk neural crest specification
$ ~2 I; A; M" v, INeural crest-endoderm interactions forming facial structures& n& L8 r, N/ _5 q: [4 s
Placode specification and separation' Z2 z" S9 {5 f1 L
Tooth development and evolution
& @2 t Q( L% \# DSemaphorins, Robo, and ephrins in neural patterning
4 A5 z3 z7 W* z2 Q$ w14. Paraxial and intermediate mesoderm
9 H! `" M4 w h2 O* A) s! dSpecification of paraxial and intermediate mesoderm
S7 B" b! t$ v3 s+ c2 K3 gEpithelialization of somites
2 M y" e, h8 b8 u6 k' aThe syndetome—where tendons arise
+ D, P0 o. b0 A# N1 i8 o0 k; SFGFs, Notch, and Wnt in somite specification and separation
% w. v( V8 }, M8 m) } |The primaxial and abaxial musculature
: }( J- H# r* M3 p1 M3 iNew sources of muscle precursor cells) R* x6 ?# Y9 c1 i
Pathways of skeleton formation
2 ^! z3 C. p5 }5 MRegulating ureteric bud branching8 [7 R8 n+ I$ U- T
Wnt and FGF proteins regulating nephron formation
) R& k4 `# u5 F+ c6 D1 Q+ G* w15. Lateral plate mesoderm and endoderm
! E6 X M$ a- Y2 J" J% K+ lCloaca formation
7 b$ u+ U0 X; d; }% HHeart cell specification% {# r* W2 F$ \9 p1 }$ g
Tbx genes, retinoic acid and heart chamber formation
# @7 x+ e- [0 P$ d9 ?" vHeart valve development
; j5 F3 s( L, _+ H& Z9 K) J! `Hematopoietic stem cells and their derivatives5 f" f9 s% l0 x4 k0 r* W* }
Lymphatic development
1 f) `' t1 a" t4 e! ~! U% Y/ nInduction of arteries by neurons
( j) g, J4 @' u9 B1 N1 C$ r% x) e" ?+ BPlacenta as source of blood stem cells
; W3 K% @$ f, Y K1 w* U' nAdult blood stem cell niches! e5 ?4 @) O: F; W
Endoderm specificity
! \# w' x* K# X! g6 P* sPancreas vs. liver development
# e/ `, h. ]# I9 b( n; H; o4 }Fate mapping pancreatic cells! O* i$ D, F% u) v1 w7 w4 _1 a
16. Development of the tetrapod limb
# m' M8 L1 |( tHox code of limb development
+ ~8 ~. w9 x7 m. Q9 ?Specification of the digits by hedgehog proteins and HoxD genes
# F! j( r$ Q6 o& n# b u" kControversy over digit identities in dinosaurs and birds
" j0 u' x3 g. U. h, h, g. PGetting limbs from fins
4 o# g2 D3 ?. D/ P2 M6 H17. Sex determination
0 D+ F6 X1 U7 b& N( aTiming and gene expression in mammalian sex determination
' e h) `/ ~7 {3 _1 XBrain sex determination pathways in vertebrates and flies
7 x" g4 ?0 U9 `- y/ o& [* }( n) ?Hormone disruptors and sex determination problems
9 c0 b$ w0 r* ODosage compensation and sex determination s1 }- i2 H" `2 e: V4 G$ L
Temperature-dependent sex determination in turtles3 x2 |: V6 W1 I
18. Metamorphosis, regeneration, and aging3 u; b0 T+ v$ d2 v0 G+ {
Molecular mechanisms of amphibian metamorphosis
/ L9 ^% ?" V' ~8 D) g& _Ecdysone receptors and the response to molting hormone. W7 ^0 q! s6 P+ m2 t P' c& O
Compartment formation in the wing imaginal disc
4 D& u5 {$ s. l3 R% RWhy can’t we regenerate our limbs?4 m; l \ @# ~8 ]3 \/ _/ w* L
Neuron- and mesenchyme-dependent stages of limb regeneration0 F q( U1 Q% D$ p6 v" a% @
Specification of limb regions by transcription factors during regeneration
* C1 ]$ j4 G4 T7 Q: ?Mitochondrial control of aging$ I" Q: n! k) T4 R
Insulin pathway control of aging and possible relation to oxygen radicals+ i! U+ h; a# x: V
“Ageless” animals and environmental control of aging8 G# X# _% L3 a1 Q" r; n
19. The saga of the germ line
2 j* e/ l6 k( M; N! @4 m, D# L" mGenetic specification of germ-line cells in Drosophila and vertebrates: m X& T2 k" ~0 V7 P
Components of the Drosophila germ plasm; D6 `# {+ [9 x7 o
Egg and sperm stem cell niches in Drosophila
: O0 x) f$ b( ]8 s) j7 `3 K+ ^Migration of primordial germ cells in mammals, chicks, and flies+ W! D u5 M2 g/ O* ]
Determination of meiosis and mitosis in C. elegans* p- ~7 ?& _) M9 s2 ?% C
Retaining mammalian spermatic stem cells
7 X" d/ Z! X( K2 FIV. Ramifications of Developmental Biology, @& ?' K8 c, Z0 c6 |! R$ r
20. An overview of plant development- w, S3 L: }5 w) U8 T& a I
Gamete formation and pollen tube guidance# P( Q/ r- ~ q0 h
Maternal effects and embryo development
* a% d3 i1 I$ M5 O- s% QRadial and axial patterning
' n$ ]8 A2 |+ W; b- ~ D2 M0 @# ~8 PNew model for auxin specification of polarity5 B7 X# r/ f3 ]* f2 i: ?1 d. w, A
Roles of microRNAs in plant development- M; |. k0 a0 m( r& \5 }
Dorsal–ventral leaf patterning- _+ T1 ?3 E/ h0 f0 {+ p
Long-distance RNA transport and flowering0 ]2 A4 B$ k& P5 {! w
Floral meristem specification
! J6 D( n. a8 N9 u+ j6 I, t' ^8 e; |21. Medical implications of developmental biology
! h2 q r/ J1 z t7 g3 c2 DMechanisms of alcohol teratogenesis' |5 U2 r) q/ a9 ]$ U4 e
Effects of endocrine disruptors on human development/ R/ L. x% H2 m) n4 @/ o E
Nutritional effects of gene methylation and disease susceptibility8 x7 c1 @6 Z1 V' p- Y. }' w/ D
Cancer as a disease of development/ m' [) {, W g6 j
Cancer stem cell hypothesis/ P; R, p1 w5 Q% Q- k5 Z8 ~8 L5 {
Developmental approaches to cancer therapy5 [, _+ {# Q% d5 r" s! j; e! k
Stem cell therapeutics+ o8 Z6 W( x* F, k% m) w) v) G# [- W
Regenerating human limbs and neurons
2 @& d D$ ?) }: Z22. Environmental regulation of animal development
0 W; e6 y1 }' F: YMolecular bases for environmental regulation of gene expression% g" [9 S/ I" O a( P; W. a" G! t
• Importance of symbionts in mammalian gut and immune system6 T3 T) e8 |) I. B* O1 p- @6 q# A
development
' K8 l D( j9 vSignaling from fetal mammalian lung to initiate labor$ [7 P% }- \3 i0 F
The role of nutrition in the development of the dung beetle
- K' h/ X' I" `3 oPredator-induced polyphenism and toxicity testing# f* V. D# [8 a% h
Genetic assimilation of environmentally induced traits
- [* X2 X1 d$ _; b23. Developmental mechanisms of evolutionary change
' f ^8 i7 N0 \ y4 o xDevelopmental modularity and evolution (stickleback studies)
% _8 t: ]8 f1 L. y) kEvolution by heterochrony, heterotopy, heterometry, heterotypy9 Q: M) W: A) t& i& x
BMPs and Darwin’s finches
, l! U* k6 T; T) iOrigin of neural crest cells and the origin of jaws
/ W; v5 Q+ z, J4 Y8 e, iThe search for the Urbilaterian ancestor |
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发表于 2009-7-10 21:51
