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可是这个版本（如果是，我就给你下）：
" C( n* s2 z6 L) b) d, m; l) MTable of Contents
8 S" \$ J. v4 G( O# M0 J3 `. B
5 Q- J; g0 A4 dI. Principles of Developmental Biology
* E: k, R7 L; U4 C* g) E" N. z C- [! Q# H- ?! ]. p) {0 G
1. Developmental biology: The anatomical tradition! o$ B3 Y* _+ z$ `
New techniques of mathematical modeling of development" e9 o' p7 A+ P$ `* `* z
2. Life cycles and the evolution of developmental patterns
0 u! D9 E4 T5 t! |# K; l7 h$ ]) B5 {Recent advances in planarian regeneration5 M3 \% h! f& k/ o4 M$ C
3. Principles of experimental embryology
# K6 f! s7 V4 D( O {& E4. The genetic core of development
% R0 f5 C( f' F$ T" r: W8 t5. The paradigm of differential gene expression
, D2 ^0 ^: r; Q" J, U' V0 _, E" lHistone modifications" C' d! H% V; _7 q" d
MicroRNAs' @. |9 z' \0 I, U: N& {; C
Pioneer transcription factors+ _8 n) P9 t3 L, }
Mammalian cloning and methylation patterns
0 c+ ]) [9 ?$ u/ w! J6. Cell–cell communication in development
9 W$ _* v7 U% p3 C C' f% }" |Stem cell specification and stem cell niches
8 f7 b) \8 f7 L- A! t7 c% p0 ]Morphogenetic regulation by cadherins. r" m; v! ^: A) j4 K R9 f9 w4 s
Noncanonical Wnt pathways, [6 x+ a$ R. g& Z* _& V5 ]4 U
Dependence receptors and apoptosis
' j, i" |0 Q# i7 K+ q. G) n' ACommunity effect and autocrine factors0 G2 W8 A r: G) m
8 W( q( A8 p* Y. C
II. Early Embryonic Development; m- A/ V0 `! c# |: z, ~( G' K, w
$ z" b1 i* P! |1 K7 C2 y+ M
7. Fertilization: Beginning a new organism( G5 n. P P9 @
Cortical granule components& z, l' |2 | q( z: T( P& j$ [
New mammalian sperm–egg binding model
4 @6 _! z9 D* S( AMammalian sperm chemotaxis and thermotaxis {" Q& L, L8 o& H5 ?1 W
Mechanisms of sea urchin sperm chemotaxis" l3 |# ~1 H2 d N+ O, O0 X
Sea urchin bindin receptor% p6 j- P8 u+ N/ o
Oocyte translation inhibitors and their removal* N8 |$ }- ^5 z; H/ g1 A9 g
New hypotheses of sperm activation
: ]3 q% C2 q9 l( E7 q$ H2 fMammalian sperm–egg fusion
6 K; t, E7 L6 @$ f( F) W/ j8. Early development in selected invertebrates
8 c9 C d. M2 i4 W6 y: d% qWnt and Nodal in sea urchin axis specification
$ k g6 W( W1 o/ P! B3 ?/ m# m0 VCoiling genetics of snail embryos% y2 y% @2 V$ l6 f. N
Functions of tunicate yellow crescent4 a& i; K% z. O' _/ s& h, B
Roles of FGFs in tunicate development
& s& r; Y9 F; b' B D; t3 MTunicate heart development
- a0 x9 `; p' }9. The genetics of axis specification in Drosophila
9 Y! R# `; B9 _FGF signals and Drosophila mesoderm formation
1 ]9 O, E- Z; l) h$ k+ _& t5 ZTransport of Nanos and Bicoid messages to opposite ends of the fly oocyte' K6 m* U" k$ S/ X, o4 F
New model for gap protein stabilization
J' C S3 L4 Z/ L$ z2 i6 i10. Early development and axis formation in amphibians1 s2 k" }% K, D* q& S3 H
New models for organizer formation in Xenopus8 }% K6 a$ K& \ n# @( s
New model for mesoderm specification in Xenopus6 B* ]8 @. C }$ J; q g' C
11. The early development of vertebrates: Fish, birds, and mammals
/ t v6 ]2 s' f& iMaternal effect mutations in zebrafish
; \/ ^+ t3 f4 _+ z/ [2 GNeurulation in zebrafish
* ^4 ?+ r1 I, _5 R$ `Retinoic acid in anterior–posterior axis specification in chordates
9 N/ p- M4 Y7 `( Q8 r3 |, k# DCiliary movements and left–right axis specification in vertebrates" l4 l- Q2 q6 _3 Z/ T9 d
Role of Cerberus in chick head formation L: ~! J& B) h, |5 P
Mesoderm specification and migration in chick gastrulae
) O6 S) C9 v- e0 A1 m* WFGF and cell fate in chick and mammalian epiblasts
6 ^! Y" M* C9 V4 @( t: s% uInduction of pluripotency in mammalian inner cell mass blastomeres
# C% Q3 a. ^: DHomeotic transformation in mammals due to total Hox paralog knockouts/ j2 [1 T/ U* B: K) `/ J+ P
Controversy over blastocyst polarity in mammals; T# w: g. ?9 M4 F4 S" w$ C- i
Folate receptors and teratogens affecting neurulation5 C4 E1 y" d1 R& p# V( A5 S3 J, S) K
* q9 _ \% J/ _- O4 [! GIII. Later Embryonic Development) k% ]5 u _" i5 }: ?& _
% L/ ~6 \0 _1 ^2 L* |
12. The emergence of the ectoderm: Central nervous system and epidermis( X/ J: i: ?4 K) v, ]5 j. J
Genes specifying neural fate4 ^0 \+ @' }0 v6 |$ {, i g
Human-specific genes specifying brain growth2 o3 ^4 d5 q6 X" R
Progressive myelination of the human brain" f3 d& t* W! [3 t' [
Neural stem cells
" `, m& C+ t2 s9 `Eye development and blind cave salamanders
5 t3 Q* Y, }. J5 A* X$ vSkin, hair, and pigment stem cells: l# P1 X& h) y
13. Neural crest cells and axonal specificity
3 ~; ?/ u0 ]! p+ L9 kNeural crest cell specification and migrations
" W5 g# K5 ^. c1 N( w/ {8 ?7 O6 dHead vs. trunk neural crest specification
& ~% q' t$ @! u# K P' ^2 u& UNeural crest-endoderm interactions forming facial structures) [' e2 p- ^" b7 P/ _, L. T9 B9 j: ?
Placode specification and separation: `' \# l, q% V" {* y6 i
Tooth development and evolution
+ i5 q" E* ^, `Semaphorins, Robo, and ephrins in neural patterning
+ ^# ^; |+ i! a3 @# ~14. Paraxial and intermediate mesoderm6 n5 P7 E: p$ x) |9 @2 E
Specification of paraxial and intermediate mesoderm3 A( A. }8 k4 U
Epithelialization of somites$ m8 N& P! f4 B4 X6 E. d) l/ M4 s
The syndetome—where tendons arise) o3 O; _6 g6 b& o1 S+ v8 `
FGFs, Notch, and Wnt in somite specification and separation
& E2 W, }& ^6 R1 s! f* k# @" x6 L' y7 h' {The primaxial and abaxial musculature7 _, S4 ?$ w: t5 {2 Y
New sources of muscle precursor cells3 P8 ]& V4 ~9 }% }: A
Pathways of skeleton formation& s" @* v# C% u
Regulating ureteric bud branching$ h! o7 F9 f- I w" ^
Wnt and FGF proteins regulating nephron formation5 C* l: O' z0 C' P! h$ W7 o7 } }( y
15. Lateral plate mesoderm and endoderm
' ]6 q' i) t8 j9 \Cloaca formation
w4 N% Y8 M! u$ v( lHeart cell specification
5 q7 }" a! b- H' K9 S( n2 \1 vTbx genes, retinoic acid and heart chamber formation
8 u# W5 S. `2 j q5 ]Heart valve development
/ G8 W' S9 s' ZHematopoietic stem cells and their derivatives0 z, q0 _3 n B; J! _% o( Z
Lymphatic development- u0 |# U) j7 B& J% b/ n$ c& @
Induction of arteries by neurons7 x& I- V4 ^3 E \! w0 w
Placenta as source of blood stem cells
E' u$ p/ I c) v" ]1 Z) RAdult blood stem cell niches
3 d: Z; y( A ^, @; j4 DEndoderm specificity5 ^) z" ^8 |' Q) R+ J$ e& m) l
Pancreas vs. liver development+ L6 H9 B; m) K
Fate mapping pancreatic cells7 z3 j( N" R0 g8 M
16. Development of the tetrapod limb) |/ r. L2 z' O4 a1 L
Hox code of limb development5 u# R" u, s5 `
Specification of the digits by hedgehog proteins and HoxD genes( \2 C0 {6 j9 j+ A
Controversy over digit identities in dinosaurs and birds( g) [# p0 I7 G2 O
Getting limbs from fins
1 |# c' [* b( R4 I0 v. ?9 @) a17. Sex determination
" K$ ]4 ~6 v9 C4 Y7 HTiming and gene expression in mammalian sex determination
7 @+ V8 C7 c; T4 K+ |$ ZBrain sex determination pathways in vertebrates and flies
9 |- T8 `& b% }* k. C2 FHormone disruptors and sex determination problems
9 r6 }4 J4 x/ q# B# |" PDosage compensation and sex determination5 g+ j: \/ G1 D F" q; }) w/ t2 S5 P
Temperature-dependent sex determination in turtles
! x7 ^* C0 a5 h5 R18. Metamorphosis, regeneration, and aging
! w8 |; ], i2 |; l: V% DMolecular mechanisms of amphibian metamorphosis: c: f" p( `) v5 Q
Ecdysone receptors and the response to molting hormone* b3 ?1 }& y+ l* q
Compartment formation in the wing imaginal disc
- l* d0 D( |- `' T5 yWhy can’t we regenerate our limbs?
- R" Z, |" P: T8 M* WNeuron- and mesenchyme-dependent stages of limb regeneration. C: w3 `0 d8 @; O7 b' g/ ^
Specification of limb regions by transcription factors during regeneration% _! g, c$ o1 w4 j2 |" p
Mitochondrial control of aging( _7 ~+ S/ y5 n/ G4 g# Q2 e; {
Insulin pathway control of aging and possible relation to oxygen radicals) }" Q! a$ G6 [$ v. j
“Ageless” animals and environmental control of aging
% @' D& L# [# A19. The saga of the germ line& p* o3 j% W( k
Genetic specification of germ-line cells in Drosophila and vertebrates
$ S% W1 z! ?& l' h5 X3 RComponents of the Drosophila germ plasm
) K$ X$ m2 s% WEgg and sperm stem cell niches in Drosophila. v" g% d: k4 L5 ~& t, t
Migration of primordial germ cells in mammals, chicks, and flies6 f c6 }) |% O7 l4 U
Determination of meiosis and mitosis in C. elegans1 u! U& `3 h" f; a, j
Retaining mammalian spermatic stem cells" @1 g0 J+ s, ]- W
IV. Ramifications of Developmental Biology
) I: H1 l' `' ]0 D! k: f" i20. An overview of plant development
* x: I! y( D: V1 {$ \! `% `Gamete formation and pollen tube guidance5 N/ s1 q% [" D0 G; m
Maternal effects and embryo development
* J9 P" f, F) z+ ]3 ~Radial and axial patterning+ b! I1 x, o5 {% Y. |; J
New model for auxin specification of polarity
$ r0 P" ~3 I# \! z4 p/ M+ MRoles of microRNAs in plant development
. u0 g5 ^2 N8 MDorsal–ventral leaf patterning
6 J$ J, \+ d) ?% E+ D# RLong-distance RNA transport and flowering- p4 i" M& T! \
Floral meristem specification5 n1 _0 _; _+ m$ v) a& c& R6 G' s
21. Medical implications of developmental biology
; i3 ]; l, A6 I* _4 m, LMechanisms of alcohol teratogenesis- [8 v" z4 W& ^9 e' l# `% U9 K
Effects of endocrine disruptors on human development
N% G8 f) q$ M% FNutritional effects of gene methylation and disease susceptibility' o* U+ a9 v1 Q& K/ V6 Q% n
Cancer as a disease of development5 Q4 ~: u7 [. H
Cancer stem cell hypothesis
}8 c2 K% \ _! P4 |/ q- uDevelopmental approaches to cancer therapy
) d8 o5 ?+ @3 b: V4 t& iStem cell therapeutics( l5 [5 m* D4 f/ p. @9 ^1 ^! ~+ i
Regenerating human limbs and neurons
9 l3 `% U; @. ~$ w22. Environmental regulation of animal development
1 o. d7 M. y! G) a2 g( PMolecular bases for environmental regulation of gene expression2 E( X5 p. b0 P6 U! ~8 e/ S4 ^+ r
• Importance of symbionts in mammalian gut and immune system
7 H6 [) ~2 k) Y0 P8 ]development
" ^! L$ L) A6 a' mSignaling from fetal mammalian lung to initiate labor
% @0 Z. ` B1 `) K5 LThe role of nutrition in the development of the dung beetle6 H' d2 ~5 v4 _$ G
Predator-induced polyphenism and toxicity testing
2 r1 Q' [: J% M+ ~6 x$ z7 [Genetic assimilation of environmentally induced traits
4 I5 @/ b( O [% p4 f4 r( S23. Developmental mechanisms of evolutionary change# e. _$ l5 M2 ]8 S' G- v. H; S
Developmental modularity and evolution (stickleback studies)% r8 N3 ~+ i8 j+ O" Y; P5 p
Evolution by heterochrony, heterotopy, heterometry, heterotypy3 `5 g! G/ d5 v) H) }6 Z* s
BMPs and Darwin’s finches2 n/ R$ ]4 ~, X! K* U0 U
Origin of neural crest cells and the origin of jaws
; R% [( h5 a8 X& dThe search for the Urbilaterian ancestor |
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发表于 2009-7-10 21:51
