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- 积分
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- 威望
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可是这个版本(如果是,我就给你下):
' t- ~9 M) X) A) R- i5 TTable of Contents2 j$ P: I6 T0 F$ x+ |
- O8 F1 D7 O6 L0 x. N# FI. Principles of Developmental Biology
! Z3 @3 \' i8 L/ j; X
6 u8 f7 R0 l. C& ]1 b1. Developmental biology: The anatomical tradition, M; u2 k2 N0 h9 {, y
New techniques of mathematical modeling of development; | O: O1 v: j+ n; I
2. Life cycles and the evolution of developmental patterns; Z- B4 K# d8 {( n0 y" _% U& n I2 |; J
Recent advances in planarian regeneration
4 V5 a- |& o7 u1 }3. Principles of experimental embryology
' v, D; O7 Y0 B5 B4. The genetic core of development
6 T# c. Q# \$ K5 R" e5 v1 x5. The paradigm of differential gene expression
5 }) U6 k( z% x: Q1 f/ e8 r. bHistone modifications
, z1 x+ Z: {0 _8 J' V2 tMicroRNAs
/ V, s# I0 n: ?& i( b- RPioneer transcription factors
4 @ N5 \ p% R0 c# S# oMammalian cloning and methylation patterns
+ U y' B8 u1 w. A* O4 i6. Cell–cell communication in development
7 M% |, \/ q! g8 E! x& BStem cell specification and stem cell niches
! X7 Q" k6 v/ ?Morphogenetic regulation by cadherins d6 j! L0 t4 M2 L+ _
Noncanonical Wnt pathways% C3 s: s: X0 F
Dependence receptors and apoptosis
6 h8 e% J k& \Community effect and autocrine factors
0 X4 f0 x$ A. L/ \% W, K6 I8 F+ E
II. Early Embryonic Development
! h( }# y- ]; |" P) ^" C' n' m) @, a- |3 X. [* D
7. Fertilization: Beginning a new organism
7 L/ X( w1 T+ q- @/ mCortical granule components
" j6 m) ]; Y! V: o+ C2 c/ BNew mammalian sperm–egg binding model$ s' Q* `7 x* _2 _* y. o: t5 L
Mammalian sperm chemotaxis and thermotaxis! ]1 |* r' O: `" l- k) X3 i
Mechanisms of sea urchin sperm chemotaxis+ t$ b1 E- g$ @$ a; h
Sea urchin bindin receptor0 Q( c7 X2 a8 b( n
Oocyte translation inhibitors and their removal8 f: R3 `% L* c$ s$ x- [
New hypotheses of sperm activation& v5 N `4 O+ E+ n
Mammalian sperm–egg fusion
, j/ {' M; o$ J N8. Early development in selected invertebrates6 f$ s4 S0 i1 q5 e; ~4 A
Wnt and Nodal in sea urchin axis specification
# N3 U- T7 C2 F5 ^4 {Coiling genetics of snail embryos. k5 K1 U, q! N w* h- o* q
Functions of tunicate yellow crescent" s* s7 h& I" d4 y/ m
Roles of FGFs in tunicate development
( x, ^. I7 `& Z& x+ ^: sTunicate heart development$ R& n4 C' V; j. X- D6 m B7 L
9. The genetics of axis specification in Drosophila* U$ S- @& h: d1 s$ M2 ~
FGF signals and Drosophila mesoderm formation
) i5 y5 `, H% w+ B9 VTransport of Nanos and Bicoid messages to opposite ends of the fly oocyte. F$ c& a6 @! v6 N9 Q k
New model for gap protein stabilization1 b$ C4 ~* X5 c( e5 l
10. Early development and axis formation in amphibians1 Y5 d" V& o! Y4 k
New models for organizer formation in Xenopus$ P( Q# s6 g8 M4 {
New model for mesoderm specification in Xenopus
y! j7 n) X3 ^9 p11. The early development of vertebrates: Fish, birds, and mammals
3 |: F6 v. L( I# ?& [+ eMaternal effect mutations in zebrafish
. n E M; M! t8 U2 v, \- X: {Neurulation in zebrafish; f! B! t+ _9 k
Retinoic acid in anterior–posterior axis specification in chordates
* o' s3 T5 Z! Y H# L8 X4 yCiliary movements and left–right axis specification in vertebrates! Z3 ?% {* i' W; k8 w$ J
Role of Cerberus in chick head formation- u8 L; N0 T" \+ s" g+ T" v3 D' y
Mesoderm specification and migration in chick gastrulae& M! H! m: y9 o* D
FGF and cell fate in chick and mammalian epiblasts
/ k! Z X" Q6 L; `- C% LInduction of pluripotency in mammalian inner cell mass blastomeres
+ F; T y$ a2 j, F( @6 n8 PHomeotic transformation in mammals due to total Hox paralog knockouts: N/ ~" ]% F( h. j/ J, G3 n, x
Controversy over blastocyst polarity in mammals/ ^ l! Q! S- k6 l# P
Folate receptors and teratogens affecting neurulation; K7 l7 R! h/ ?) a( r: m; l
. @# G. b. ], D% |' W' Y. |0 L F
III. Later Embryonic Development% K$ Z& @7 w! W% t
* A. O2 M6 z% D, t! J* ^/ m: N12. The emergence of the ectoderm: Central nervous system and epidermis6 X+ Z$ v( V& @9 X v0 M+ E/ u
Genes specifying neural fate
. |5 K) c0 p1 z6 N Y$ E zHuman-specific genes specifying brain growth" L6 ], G8 f! f- H/ f3 s
Progressive myelination of the human brain0 E4 L6 w& L E+ L. G8 w
Neural stem cells. [+ A+ {- _& M1 U0 D- I
Eye development and blind cave salamanders9 o r6 A4 W' S- c" b( A
Skin, hair, and pigment stem cells0 |* g' t& r& K) e
13. Neural crest cells and axonal specificity5 @/ d* f/ M% ?% }
Neural crest cell specification and migrations- w3 f7 k6 @. m& r: Y5 {: S7 q
Head vs. trunk neural crest specification2 ]0 s0 e- H! C* C
Neural crest-endoderm interactions forming facial structures
3 c2 O# U/ B+ i2 tPlacode specification and separation, `! q" h! |# X& b! q3 I
Tooth development and evolution
; K9 l6 d( L0 v- QSemaphorins, Robo, and ephrins in neural patterning
. {1 o1 ]# T* Z N; p$ P8 R5 B14. Paraxial and intermediate mesoderm
5 x+ x& A8 N9 ?1 c% j: B; }- o8 u7 K% ASpecification of paraxial and intermediate mesoderm
0 c& U. Y7 T5 x5 U" bEpithelialization of somites
$ I3 d) r D* T XThe syndetome—where tendons arise$ F, y1 Z( S8 Q& o4 y: q
FGFs, Notch, and Wnt in somite specification and separation/ Y1 s; z$ v+ t9 B
The primaxial and abaxial musculature
s+ f6 H% x5 Y6 B. i& A% l8 b0 F5 kNew sources of muscle precursor cells3 s% O7 k0 Q9 E1 C- Z3 J$ x
Pathways of skeleton formation% m. L* h) `( m! [# s8 W' ]0 A
Regulating ureteric bud branching
9 ` h' [8 }) bWnt and FGF proteins regulating nephron formation- k1 n7 V0 J* d" T) b1 L
15. Lateral plate mesoderm and endoderm" d g& Q6 x6 Q8 e
Cloaca formation
2 p) x! M# l5 {& D' YHeart cell specification
* i0 A, T/ V) V) h. l. W9 VTbx genes, retinoic acid and heart chamber formation
/ n6 E S, X4 ?1 sHeart valve development
) Q/ m- t* Z1 m' q4 Z$ T. P: nHematopoietic stem cells and their derivatives; }5 j+ P4 J) V1 `
Lymphatic development1 Q, n7 J9 U$ y" N
Induction of arteries by neurons% e Z: Y$ ]8 s: b y& p% e
Placenta as source of blood stem cells
# l& {4 B5 c# m* @Adult blood stem cell niches5 ~4 x" ~$ ]8 z4 P1 J% u
Endoderm specificity2 Y3 F9 n5 b- I- Y" k" h4 g# s
Pancreas vs. liver development# v m# s; e' }$ x7 d: s$ f7 H5 o
Fate mapping pancreatic cells
- ^4 T# W6 N! C& @1 R+ @; D; E/ U9 W4 }16. Development of the tetrapod limb4 V3 s1 O; u0 ^
Hox code of limb development, g9 Y4 n! e9 ` [
Specification of the digits by hedgehog proteins and HoxD genes
& d9 J/ _9 ?* {9 MControversy over digit identities in dinosaurs and birds
7 D$ v# g2 a/ b/ `Getting limbs from fins
5 k! g0 n. j' d6 x17. Sex determination. W9 L* l- f' e2 K' R
Timing and gene expression in mammalian sex determination0 |' b$ ~- e9 e' W6 w
Brain sex determination pathways in vertebrates and flies8 z. w8 S* K7 _$ Z9 M
Hormone disruptors and sex determination problems
' \2 M0 [3 y% }9 P2 \0 qDosage compensation and sex determination
# \' P9 _4 o1 c, j2 XTemperature-dependent sex determination in turtles6 p- }. v3 M( f/ O
18. Metamorphosis, regeneration, and aging
. x- @5 V4 h; r: A" f' n# Z" E7 ZMolecular mechanisms of amphibian metamorphosis
* _! a) p7 w2 {9 f7 W- kEcdysone receptors and the response to molting hormone
: }5 i8 O4 w9 i- d ECompartment formation in the wing imaginal disc G9 `+ l7 \; F* S5 \! }
Why can’t we regenerate our limbs?
; b6 L7 f; i+ ?4 y |Neuron- and mesenchyme-dependent stages of limb regeneration
/ t) P8 H+ v3 |8 MSpecification of limb regions by transcription factors during regeneration$ v6 c4 s2 X( j, b: }- s5 d% u
Mitochondrial control of aging
5 Z5 @1 [# ]- w: DInsulin pathway control of aging and possible relation to oxygen radicals" C6 m; a$ t2 a' y! r1 E; G. C# d
“Ageless” animals and environmental control of aging6 ~8 `" |7 C3 a$ w
19. The saga of the germ line
3 ^5 W4 M1 {( |/ j3 l4 K8 q( Z0 j3 JGenetic specification of germ-line cells in Drosophila and vertebrates
" U3 L2 Q+ E5 R y HComponents of the Drosophila germ plasm
8 X( t ]3 x$ a" f' |Egg and sperm stem cell niches in Drosophila% G: Y: p6 W5 y$ R
Migration of primordial germ cells in mammals, chicks, and flies& B L& C) T# o0 D% K: o
Determination of meiosis and mitosis in C. elegans' S: z: c/ V. e3 R( C( d9 j# {2 K
Retaining mammalian spermatic stem cells
. |( |. ~3 D* _0 w. c, J) XIV. Ramifications of Developmental Biology
7 k* |: ~9 ^9 t" k! T/ V0 e20. An overview of plant development" {$ l+ Q7 J6 `2 ]5 W. H. a
Gamete formation and pollen tube guidance
: d* x! d/ t( `% Q: n. ?Maternal effects and embryo development* z- E6 }" ~8 B
Radial and axial patterning2 Q* r5 D6 ~/ O
New model for auxin specification of polarity
5 D& a6 \3 \7 ^. sRoles of microRNAs in plant development6 N! i* t" O, l e: k0 ^- r: ~
Dorsal–ventral leaf patterning
5 M: o; W& r0 \- ]& I3 U4 hLong-distance RNA transport and flowering
( l$ R- o& E1 {! fFloral meristem specification
& \8 T6 v/ o& N# F5 {5 G, j21. Medical implications of developmental biology
# }5 d8 s, e" I7 s: ?1 v4 \Mechanisms of alcohol teratogenesis$ T7 H7 `: I& o( o' ]6 }2 W; `, S
Effects of endocrine disruptors on human development
) y& W2 e; m* ] P6 m7 XNutritional effects of gene methylation and disease susceptibility1 o; o" h' G2 b) [4 Z, H
Cancer as a disease of development
5 ^7 D8 ]/ r3 \7 C2 l; c* aCancer stem cell hypothesis
4 N* D( R; B9 \, J8 YDevelopmental approaches to cancer therapy
* ~& S/ {2 k9 K- qStem cell therapeutics
$ c; Y" f( p9 a' S" O, yRegenerating human limbs and neurons
9 H: u7 S6 x& i V" i. {( P, C22. Environmental regulation of animal development. P; ?, H# q0 w/ N
Molecular bases for environmental regulation of gene expression' M6 I" S6 {9 R( G7 K# V
• Importance of symbionts in mammalian gut and immune system5 h9 a A* ~! q5 v
development4 r. R3 r+ b, I* t2 |
Signaling from fetal mammalian lung to initiate labor
" W: Q- ~* I" y* s! n' _# TThe role of nutrition in the development of the dung beetle
' ~3 v4 K n# l: l1 T7 c2 rPredator-induced polyphenism and toxicity testing
) P/ t- \5 @$ U- n* qGenetic assimilation of environmentally induced traits1 G5 o, C' G4 o" j) e7 s. w- j
23. Developmental mechanisms of evolutionary change
% o) ^- k& p3 d6 ]Developmental modularity and evolution (stickleback studies)! @7 n) `' D2 E+ N
Evolution by heterochrony, heterotopy, heterometry, heterotypy
% W8 U/ K9 e: \4 c8 V0 U) b# CBMPs and Darwin’s finches
$ I; P& c1 u& TOrigin of neural crest cells and the origin of jaws6 E7 D' J) c/ W# R( l7 H& M
The search for the Urbilaterian ancestor |
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