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Handbook of RNA Biochemistry. 2 Vol.Set
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1 e: x8 U; N0 w, hHandbook of RNA Biochemistry. 2 Vol.Set6 r$ n: d3 V: p; u, E' I
By Roland Karl Hartmann, Albrecht Bindereif, Astrid Schön, Eric Westhof) A( B% P2 j& T" m& D/ o
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Publisher: Wiley-VCH
9 w% _3 X- u9 ZNumber Of Pages: 973 2 o6 t1 b, m; } P+ q& A7 U
Publication Date: 2005-05-06 8 J2 N8 [$ a0 Y3 P
ISBN-10 / ASIN: 3527308261
' P1 B w8 `9 l: WISBN-13 / EAN: 9783527308262 & R2 c' ], }2 H% ?4 J
Binding: Hardcover
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This all-in-one compendium of current laboratory techniques for the study of RNA brings together numerous novel methods that were hitherto only available through the primary literature. The editors - themselves experienced RNA researchers - have gathered expert authors from the US and Europe for the ultimate in everyday working knowledge. In more than 300 detailed protocols, all the techniques covered are treated with the user in mind, including practical advice and an invaluable "troubleshooting" section.9 A; H+ Z( f: |; ?
The broad scope of the book allows the side-by-side treatment of specialized methods with basic biochemical techniques for the isolation, characterization and functional analysis of RNA. All pertinent laboratory methods are presented in detail, including
8 Y8 N. p! F1 I) B4 C9 q& `5 R+ RNA synthesis, modification and ligation
6 t8 N& ]0 Q* X, h N+ Sequence and structure determination of RNA4 q4 p# }$ C* ]& E0 A& @% A
+ Isolation and purification of ribonucleoproteins( V( G4 y8 D9 U
+ RNA crystallization
1 Z0 r: U+ Z4 M4 p8 J+ Single molecule studies on RNA- ~4 E9 w; u5 W: ?( a; _
+ Analysis of splice variants2 p. M- q9 \+ e, A6 M3 J7 }- S
+ RNA imaging in vivo3 n4 k8 S5 x5 M! w1 x8 Y
+ Modeling and prediction of RNA structure: k7 P# m, `: I" L- p; B+ s! x
+ RNA microarrays ~- G' S4 f$ Z! z) f; l6 W
+ Aptamer libraries and SELEX technology
0 ]$ {' _6 d8 A& R7 k+ RNA interference4 Z2 B8 s5 o' R& m8 o
In short, a guide to successful experimentation for molecular biologists, biochemists and biotechnologists and of interest to every researcher experimenting with RNA.
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Summary: RNA( Q. `+ d6 P7 ?
Rating: 4
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This is the perfect addition to anyone's library who works with RNA. It covers all relevant areas, though it could have had a little more on RNA interferance, and related small RNAs. The only drawback (besides the price) is that this is a two volume set, so be prepared for a nice big bulky package to come.& [- R. ?# X r/ J* i# ?/ b
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