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本帖最后由 细胞海洋 于 2010-1-19 08:22 编辑
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Genes and common diseases presents an up-to-date. w, o8 y7 r( p" [; d! I
view of the role of genetics in modern medicine,
2 X# T2 X2 ~! Y% rreflecting the strengths and limitations of a genetic3 g' R, }- s. Y& d6 Q
perspective.
( o) |7 k: T3 m! o Q9 ^5 QThe current shift in emphasis from the study of
8 ^1 p* w) o* i2 g! Q Lrare single gene disorders to common diseases2 O8 u0 Y; a$ h. ]
brings genetics into every aspect of modern
! u) E; R" a. ymedicine, from infectious diseases to therapeutics.! D [; q0 M8 ^' J; ^; K: q
However, it is unclear whether this increasingly
% A) y9 k/ i/ v7 y k* ^8 ~genetic focus will prove useful in the face of major/ e# A8 q' z7 n2 O/ x2 e8 @
environmental influences in many common
$ l! P. p: D; f' Ddiseases.' ?* J/ t4 X4 h& x6 \, M4 q
The book takes a hard and self-critical look at
5 x( d7 s+ i2 y3 v- Y8 F4 z' I& Gwhat can and cannot be achieved using a genetic
1 ~% g5 A* l' ?( x/ \; Zapproach and what is known about genetic and" M5 o! j% y- S
environmental mechanisms in a variety of
4 r& n& j5 M, ~" \ i& i1 fcommon diseases. It seeks to clarify the goals of% N* ^1 F! A6 D9 q* f
human genetic research by providing state-of-the
5 a6 y3 q3 v5 S3 sart insights into known molecular mechanisms
' J, V4 {) A$ W1 ~9 {0 n9 Nunderlying common disease processes while at the# B) E5 r3 E: k- u b& \
same time providing a realistic overview of the
3 F* F8 K% i. ?; vexpected genetic and psychological complexity.( S- z6 Q& p9 `8 s1 Y/ |7 l0 n
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