
- 积分
- 196
- 威望
- 196
- 包包
- 805
|
1、 Cross DA, Alessi DR, Cohen P, et al. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature.1995;378:785–9.
& T+ ]+ c! s5 y4 ]; x; X
" i6 q) S& W7 q- @; ?1 Z& b2、Greber B, Lehrach H, Adjaye J. Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal. Stem Cells. 2007;25:455–64. s* e, R! ^2 O2 r$ R( h' G% u6 R
9 d+ r$ D2 b0 q4 i3 T: D
3、Babaie Y, Herwig R, Greber B, et al. Analysis of Oct4- dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells. 2007;25: 500–10.
( Y! n. n5 E. v; C) O, L# V4 Z/ q
9 {1 b u5 k' D4、Herpin A, Cunningham C. Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes. FEBS J. 2007;274:2977–85
9 Y# P$ M$ Z/ m0 [: E. W3 v# U5 _' k L+ T* M, h2 b9 p
5、Xu RH, Chen X, Li DS, et al. BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol. 2002;20:1261–64.3 y* g! ^! D" z& E/ U: o! F
+ u/ T6 Y6 d4 t) p! }- \
6、McLean AB, D’Amour KA, Jones KL, et al. Activin A efficiently specifies definitive endoderm from human embryonic stem cells
0 `" P9 T( p: Y! g7 ~7 Yonly when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells. 2007;25:29–38.% M T, R; m& Q& G( Q8 L" x
- O9 m6 E* o3 @! s: ^/ O8 R7、D’Amour KA, Agulnick AD, et al. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol. 2005;23:1534–41.& N3 \7 }6 F1 a1 [8 t" b& p
2 I3 P0 D' I3 @$ O3 Y( H/ R( ^
8、Li J, Wang G, Wang C, et al. MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal. Differentiation. 2007;75:299–307
, |: V1 A+ c; x! w& a9 {( Q8 S8 d' U3 ^
9、Ludwig TE, Levenstein ME, Jones JM, et al. Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol. 2006;24:185–7.
& l2 n* L' ]! s; n# @+ s1 i0 ]: Q/ v7 {6 S$ d3 q' a3 \ {/ K
10、Niwa H, Miyazaki J, Smith, AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells.Nat Genet. 2000;24:372–6. |
|