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发表于 2010-5-6 08:42 |只看该作者 |正序浏览 |打印

iPS cell publications & timeline' U% W; p9 K# x, ~
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Shinya Yamanaka, Pluripotency and Nuclear Reprogramming, Keystone conference, 28 March 2006; www.keystonesymposia.org/Meetings/ViewPastMeetings.cfm?MeetingID=786
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Shinya Yamanaka, Identification Of Factors That Generate ES-Like Pluripotent Cells From Fibroblast Culture, ISSCR meeting, Toronto, July 2006; www.abstractonline.com/viewer/viewAbstractPrintFriendly.asp?CKey={23482185-19E3-4771-B8CF-FDBD125BAB66}&SKey={9426630B-B824-4F8F-93F7-6C940384237C}&MKey={743B38D5-9EAD-49CC-B2C5-497EBCE87271}&AKey={70E49A1A-9665-43B3-8BAA-55C6A8F9A624}8 @( t, P% d$ X1 y( k0 J
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Gretchen Vogel,“Four genes confer embryonic potential”, Science 313, 27, 7 July 2006; published online 3 July 2006; doi: 10.1126/science.313.5783.27
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Erika Check, “Simple recipe gives adult cells embryonic powers”, Nature 442, 11, 6 July 2006; published online 4 July 2006; doi: 10.1038/442011a
PEER-REVIEWED PUBLICATIONS! ?/ m1 A" ^8 a) d4 N' p
(Primary research literature, excluding commentaries)
(NOTE: bolding to emphasize important points, yellow highlight for human iPS cells)$ T. g3 \. t' q- n( B
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Takahashi K and Yamanaka S, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell 126, 663-676, 25 August 2006, doi: 10.1016/j.cell.2006.07.024
2.
Okita K et al., Generation of germline-competent induced pluripotent stem cells, Nature 448, 313-317, 19 July 2007; online 6 June 2007, doi: 10.1038/nature05934* i8 x2 r4 o8 }% t$ X, u
3.
Wernig M et al., In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state, Nature 448, 318-324, 19 July 2007; published online 6 June 2007, doi: 10.1038/nature05944
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Maherali N et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution, Cell Stem Cell 1, 55-70, July 2007; published online 6 June 2007, doi: 10.1016/j.stem.2007.05.014# u9 }; B0 A3 H* l6 U
5.
Meissner A et al., Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells, Nature Biotechnology 25, 1177-1181, October 2007; published online 27 August 2007, doi: 10.1038/nbt1335# b7 F" U$ V  s" R; I
6.
Blelloch R et al., Generation of induced pluripotent stem cells in the absence of drug selection, Cell Stem Cell 1, 245-247, Sept 2007, doi: 10.1016/j.stem.2007.08.008. k, Q3 s! J6 q4 {* T
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Takahashi K et al., Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell 131, 861-872, 30 November 2007; published online 20 November 2007, doi: 10.1016/j.cell.2007.11.019, u" T4 e' w1 `
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Yu J et al., Induced pluripotent stem cell lines derived from human somatic cells, Science 318, 1917-1920, 21 December 2007, published online 20 November 2007, doi: 10.1126/science.1151526
9.
Nakagawa M et al., Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts, Nature Biotechnology 26, 101-106, January 2008, published online 30 November 2007, doi: 10.1038/nbt1374! I5 q" r2 n) g! T; l0 q
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Hanna J et al., Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin, Science 318, 1920-1923, 21 December 2007, online 6 Dec 2007, doi: 10.1126/science.1152092
FAMILY RESEARCH COUNCIL WASHINGTON, D.C. 20001 202-393-2100 www.frc.org' y& }$ T# n1 a; a, {8 N* u
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Park I-H et al., Reprogramming of human somatic cells to pluripotency with defined factors, Nature 451, 141-147, 10 January 2008, published online 23 December 2007, doi: 10.1038/nature06534
12.
Wernig W et al., C-Myc is dispensable for direct reprogramming of mouse fibroblasts, Cell Stem Cell 2, 10-12, 10 January 2008, published online 28 December 2007, doi: 10.1016/j.stem.2007.12.0014 ]- s4 m5 u; @
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Yamanaka S, Induction of pluripotent stem cells from mouse fibroblasts by four transcription factors, Cell Proliferation 41 (suppl 1), 51-56, January 2008, doi: 10.1111/j.1365-2184.2008.00493.x (www3.interscience.wiley.com/journal/119410896/abstract)
14.
Brambrink T et al. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells, Cell Stem Cell 2, 151–159, 7 February 2008, online 6 February 2008, doi: 10.1016/j.stem.2008.01.0044 Q$ Y0 B5 {1 U/ s; Q
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Aoi T et al., Generation of pluripotent stem cells from adult mouse liver and stomach cells, Science 321, 699-702, corrected 1 August 2008; published online 14 February 2008, doi:10.1126/science.1154884
16.
Stadtfeld M et al., Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse, Cell Stem Cell 2, 230-240, March 2008, published online 14 February 2008, doi:10.1016/j.stem.2008.02.001! s) p- T: l  B* n7 t  V
17.
Lowry WE et al., Generation of human induced pluripotent stem cells from dermal fibroblasts, Proc. Natl. Acad. Sci. USA 105, 2883-2888, 26 February 2008; published online 16 February 2008, doi: 10.1073/pnas.0711983105' Y* k- j+ d% p! T) F
18.
Wernig M et al., Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson’s disease, Proc. Natl. Acad. Sci. USA 105, 5856-5861, 15 April 2008, doi: 10.1073/pnas.08016771051 ~8 a) r% S+ T9 S; p
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Hanna J et al., Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency, Cell 133, 250-264, 18 April 2008, doi: 10.1016/j.cell.2008.03.028+ ^* C& I2 `% c3 _
20.
Schenke-Layland K et al., Reprogrammed Mouse Fibroblasts Differentiate into Cells of the Cardiovascular and Hematopoietic Lineages, Stem Cells 26, 1537-1546, June 2008; published online 1 May 2008, doi: 10.1634/stemcells.2008-0033% Y6 g( d$ w! d( Y( F% ^& J1 Y
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Liao J et al., Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors, Cell Research 18, 600-603, May 2008, doi: 10.1038/cr.2008.51
22.
Stadtfeld M et al., Reprogramming of pancreatic β cells into induced pluripotent stem cells, Current Biology 18, 890-894, 24 June 2008, published online 22 May 2008, doi: 10.1016/j.cub.2008.05.010. n, a8 [1 I& A, |; x
23.1 ]: ~1 S$ O$ Y& L3 E; [
Mikkelsen TS et al., Dissecting direct reprogramming through integrative genomic analysis, Nature 454, 49-56, 3 July 2008; published online 28 May 2008, doi: 10.1038/nature07056
24.
Mali P et al. Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts, Stem Cells 26, 1998-2005, Sept 2008; published online 29 May 2008, doi:10.1634/stemcells.2008-0346
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Shi Y et al., A combined chemical and genetic approach for the generation of induced pluripotent stem cells, Cell Stem Cell 2, 525-528, June 2008, doi: 10.1016/j.stem.2008.05.011
26.
Huangfu D et al., Induction of pluripotent stem cells by defined factors in greatly improved by small-molecule compounds, Nature Biotechnology 26, 795-797, July 2008; published online 22 June 2008, doi: 10.1038/nbt1418
27.# `. U. K  F1 s9 z  N* {
Park I-H et al. Generation of human-induced pluripotent stem cells, Nature Protocols 3, 1180-1186, July 2008; published online 26 June 2008, Corrected online 4 September 2008, doi: 10.1038/nprot.2008.92' s& [% o5 ]# `
FAMILY RESEARCH COUNCIL WASHINGTON, D.C. 20001 202-393-2100 www.frc.org
28.
Kim JB et al., Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors, Nature 454, 646-650, 31 July 2008; published online 29 June 2008, doi: 10.1038/nature07061# |+ q6 _% u8 B6 A' \# y2 }1 V
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Wernig M et al., A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types, Nature Biotechnology 26, 916-924, August 2008; published online 1 July 2008; doi: 10.1038/nbt1483
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Duinsbergen D et al., Induced pluripotency with endogenous and inducible genes, Experimental Cell Research 314, 3255-3263, 15 October 2008, published online 9 July 2008, doi: 10.1016/j.yexcr.2008.06.024% \! f; l) D1 F! O5 {0 q
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Narazaki G et al., Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cell, Circulation 118, 498-506, 29 July 2008, published online 14 July 2008, doi: 10.1161/CIRCULATIONAHA.108.769562
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Mauritz C et al., Generation of functional murine cardiac myocytes from induced pluripotent stem cells, Circulation 118, 507-517, 29 July 2008, published online 14 July 2008, doi: 10.1161/CIRCULATIONAHA.108.778795
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Eminli S et al., Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression, Stem Cells 26, 2467-2474, October 2008; published online 17 July 2008, doi: 10.1634/stemcells.2008-0317
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Dimos JT et al., Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons, Science 321, 1218-1221, 29 August 2008; published online 31 July 2008, doi: 10.1126/science.1158799
35.
Marson A et al., Wnt signaling promotes reprogramming of somatic cells to pluripotency, Cell Stem Cell 3, 132-135, 7 August 2008, doi: 10.1016/j.stem.2008.06.019
36.
Park I-H et al., Disease-specific induced pluripotent stem cells, Cell 134, 877-886, 5 Sept 2008; published online 7 August 2008, doi: 10.1016/j.cell.2008.07.041
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Tateishi K et al., Generation of insulin-secreting islet-like clusters from human skin fibroblasts, Journal of Biological Chemistry 283, 31601-31607, 14 November 2008, published online 9 Sept 2008, DOI: 10.1074/jbc.M806597200
38.
Maherali N et al., A high-efficiency system for the generation and study of human induced pluripotent stem cells, Cell Stem Cell 3, 340-345, 11 Sept 2008, doi: 10.1016/j.stem.2008.08.003
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Hockemeyer D et al., A drug-inducible system for direct reprogramming of human somatic cells to pluripotency, Cell Stem Cell 3, 346-353, 11 Sept 2008, doi: 10.1016/j.stem.2008.08.014
40.
Stadtfeld M et al., Induced pluripotent stem cells generated without viral integration, Science 322, 945-949, 7 November 2008; published online 25 Sept 2008, doi: 10.1126/science.1162494
41.
Qin D et al., Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors, Journal of Biological Chemistry 283, 33730-33735, 28 November 2008; published online 1 October 2008, doi: 10.1074/jbc.M806788200- G7 l* S/ h- o8 D. W. S7 \
42.
Okita K et al., Generation of mouse induced pluripotent stem cells without viral vectors, Science 322, 949-953, 7 November 2008; published online 9 October 2008, doi: 10.1126/science.1164270; H1 r& _' |; y3 ~3 o
43.: ~4 G$ q. n6 W- s. V
Huangfu D et al., Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2, Nature Biotechnology 26, 1269-1275, published online 12 October 2008, doi: 10.1038/nbt.1502& w' k$ x9 F6 @' v0 [7 Z* Y0 H
44.  S$ z% {0 c' O9 v# ?
Aasen T et al., Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes, Nature Biotechnology 26, 1276-1284, November 2008; published online 17 October 2008, doi:10.1038/nbt.1503
FAMILY RESEARCH COUNCIL WASHINGTON, D.C. 20001 202-393-2100 www.frc.org
45.
Silva J et al., Promotion of reprogramming to ground state pluripotency by signal inhibition, PLoS Biology 6(10): e253, published 21 October 2008, doi:10.1371/journal.pbio.0060253
46.
Shi Y et al., Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds, Cell Stem Cell 3, 568-574, 6 November 2008, doi: 10.1016/j.stem.2008.10.004" R* |! `; Q# Y( c$ x
47.
Zhao Y et al., Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation, Cell Stem Cell 3, 475-479, 6 November 2008, doi: 10.1016/j.stem.2008.10.002
48.& d5 ]  {% [% k3 R+ G0 G8 Z
Varas F et al., Fibroblast derived induced pluripotent stem cells show no common retroviral vector insertions, Stem Cells 27, 300-306, February 2009, published online November 13, 2008; doi:10.1634/stemcells.2008-06968 _" P3 f3 v( G' u. W* k
49.
Liu H et al., Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts, Cell Stem Cell 3, 587-590, 4 December 2008, 10.1016/j.stem.2008.10.014
50.
Sommer CA et al., iPS Cell Generation Using a Single Lentiviral Stem Cell Cassette, Stem Cells 27, 543-549, March 2009, published online December 18, 2008, doi: 10.1634/stemcells.2008-1075# Q# B& I+ `0 e( B
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Ebert AD et al., Induced pluripotent stem cells from a spinal muscular atrophy patient, Nature 457, 277-280, 15 January 2009; published online 21 December 2008; doi:10.1038/nature07677
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Carey BW et al., Reprogramming of murine and human somatic cells using a single polycistronic vector, Proc. Natl. Acad. Sci. USA 106, 157-162, 6 January 2008, published online 24 December 2008, doi: 10.1073/pnas.0811426106
53.
Choi K-D et al., Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells, Stem Cells 27, 559-567, March 2009, published online 8 January 2009, doi: 10.1634/stemcells.2008-0922- L2 [7 P  K8 l$ O3 N
54.
Liao J et al., Generation of Induced Pluripotent Stem Cell Lines from Adult Rat Cells, Cell Stem Cell 4, 11-15, 9 January 2009, doi: 10.1016/j.stem.2008.11.013$ F" R" b; Y* O0 g
55.3 r+ E( B3 O! Q. F4 s6 Q4 r  _
Li W et al., Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors, Cell Stem Cell 4, 16-19, 9 January 2009, doi: 10.1016/j.stem.2008.11.014
56.
Feng B et al., Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb, Nature Cell Biology 11, 197-203, February 2009, published online 11 January 2009; doi: 10.1038/ncb1827
57.
Markoulaki S et al., Transgenic mice with defined combinations of drug-inducible reprogramming factors, Nature Biotechnology 27, 169-171, February 2009; published online 18 January 2009; doi:10.1038/nbt.1520& p% E% I; X) M2 M
58.
Xu D et al., Phenotypic correction of murine hemophilia A using an iPS cell-based therapy, Proc. Natl. Acad. Sci. USA 106, 808-813, 20 January 2009, doi: 10.1073/pnas.0812090106, v. U& v7 \: J. k
59.
Park TS et al., Derivation of Primordial Germ Cells From Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved By Co-Culture With Human Fetal Gonadal Cells, Stem Cells 27, 783-795, published online 22 January 2009, doi: 10.1002/stem.13. U/ P. Z4 Y* l1 t' d
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Sridharan R et al., Role of the Murine Reprogramming Factors in the Induction of Pluripotency, Cell 136, 364–377, 23 January 2009, doi: 10.1016/j.cell.2009.01.001
61.
Kim JB et al., Oct4-Induced Pluripotency in Adult Neural Stem Cells, Cell 136, 41l-419, 6 February 2009, doi: 10.1016/j.cell.2009.01.023; t/ s3 j! y3 w
FAMILY RESEARCH COUNCIL WASHINGTON, D.C. 20001 202-393-2100 www.frc.org! Q# K7 p# Q# x+ s
62.
Marion RM et al., Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells, Cell Stem Cell 4, 141-154, 6 February 2009, doi: 10.1016/j.stem.2008.12.010
63.
Zhang J et al., Functional cardiomyocytes derived from human induced pluripotent stem cells, Circulation Research 104, e30-e41, published online 12 February 2009, doi: 10.1161/CIRCRESAHA.108.1922375 @' v3 }& {- e
64.  m( ?/ W5 V2 [
Chang C-W et al., Polycistronic Lentiviral Vector For Hit and Run Reprogramming Of Adult Skin Fibroblasts To Induced Pluripotent Stem Cells, Stem Cells 27, 1042-1049, May 2009, published online 12 February 2009, doi: 10.1002/stem.39
65.
Senju S et al., Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells, Stem Cells 27, 1021-1031, May 2009, published online 13 February 2009, doi: 10.1002/stem.33- I' ~# a) y% j6 A! ]' {6 \
66.
Guo G et al., Klf4 reverts developmentally programmed restriction of ground state pluripotency, Development 136, 1063-1069, 1 April 2009, published online 18 February 2009, doi:10.1242/dev.030957
67.
Karumbayaram S et al., Directed Differentiation of Human Induced Pluripotent Stem Cells Generates Active Motor Neurons, Stem Cells 27, 806-811, April 2009, published online 23 February 2009 doi: 10.1002/stem.31" J5 I: a% U! w$ e2 N
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Shao L et al., Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame, Cell Research 19, 296-306, March 2009, published online 24 February 2009,. doi: 10.1038/cr.2009.207 r% E& u8 l2 w7 @
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Taura D et al., Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells, FEBS Letters 583, 1029-1033, 18 March 2009, published online 27 February 2009, doi: 10.1016/j.febslet.2009.02.031
70.. H$ Y( v: |6 \& {" e- Y
Chambers SM et al., Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling, Nature Biotechnology 27, 275-280, March 2009; published online 1 March 2009; doi:10.1038/nbt.1529
71." O! E' Z2 a- x' e; [1 n  ?" \
Kaji K et al., Virus-free induction of pluripotency and subsequent excision of reprogramming factors, Nature 458, 771-775, 9 April 2009, published online 1 March 2009, doi: 10.1038/nature07864
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Woltjen K et al., piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells, Nature 458, 766-770, 9 April 2009, published online 1 March 2009, doi: 10.1038/nature078633 _( B5 `$ y) {' A; X7 j
73.9 k& U" w& u  L+ i+ z
Zhang D et al., Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells, Cell Research 19, 429-438, April 2009, published online 3 March 2009, doi: 10.1038/cr.2009.28
74." J& T5 J) |7 k; V# w5 w% a
Soldner F et al., Parkinson’s disease patient-derived induced pluripotent stem cells free of viral reprogramming factors, Cell 136, 964-977, 6 March 2009, doi: 10.1016/j.cell.2009.02.013
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Loh Y-H et al., Generation of induced pluripotent stem cells from human blood, Blood published online 18 March 2009, doi: 10.1182/blood-2009-02-204800
76.
Yu J et al., Human induced pluripotent stem cells free of vector and transgene sequences, Science 324, 797-801, 8 May 2009, published online 26 March 2009, doi: 10.1126/science.1172482
77.1 E3 `: M0 ]; y! `# j1 K0 S4 H
Deng J et al., Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming, Nature Biotechnology 27, 353-360, April 2009; published online 29 March 2009; doi:10.1038/nbt.1530
FAMILY RESEARCH COUNCIL WASHINGTON, D.C. 20001 202-393-2100 www.frc.org
78.
Ball MP et al., Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells, Nature Biotechnology 27, 361-368, April 2009, published online 29 March 2009, doi: 10.1038/nbt.1533+ h; l0 s% l9 k9 g; c8 m  `9 ^
79.1 P/ k' G) \9 m% ?* }. b0 X' n; A$ Y
Yusa K et al., Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon, Nature Methods published online 31 March 2009, doi:10.1038/nmeth.1323# A+ {2 M6 v8 Q5 H$ s& [0 H! @3 N
80.
Judson RL et al., Embryonic stem cell-specific microRNAs promote induced pluripotency, Nature Biotechnology 27, 459-461, May 2009, published online 12 April 2009, doi: 10.1038/nbt.1535
81.+ Y" O6 f) V9 A5 Q8 k4 _# X
Hirami Y et al., Generation of retinal cells from mouse and human induced pluripotent stem cells, Neuroscience Letters 458, 126-131, 24 July 2009, published online 18 April 2009, doi: 10.1016/j.neulet.2009.04.0354 l$ m2 ~# x/ P; K8 l1 o
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Esteban MA et al., Generation of induced pluripotent stem cells lines from Tibetan miniature pig, Journal of Biological Chemistry published online 21 April 2009, doi:10.1074/jbc.M109.0089383 N& S1 D* W  }- _! P! ^$ t4 D
83.- c: j, N! L9 M) M
Zhou H et al., Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins, Cell Stem Cell 4, 381-384, 8 May 2009, published online 23 April 2009, doi:10.1016/j.stem.2009.04.005" F/ k5 h) V  t. I' u! |$ d
84.
Hotta A et al., Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency, Nature Methods 6, 370-376, May 2009, published online 26 April 2009, doi:10.1038/nmeth.1325
85.
Tashiro K et al., Efficient adipocyte and osteoblast differentiation from mouse induced pluripotent stem cells by adenoviral transduction, Stem Cells published online 30 April 2009, doi: 10.1002/stem.108* @6 c  \& [6 S, e1 \3 Y0 ]- c$ q, i
86.
Taura D et al., Induction and isolation of vascular cells from human-induced pluripotent stem cells, Arteriosclerosis Thrombosis and Vascular Biology published online 7 May 2009, doi: 10.1161/ATVBAHA.108.182162
87.
Lyssiotisa CA et al., Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4, Proc. Natl. Acad. Sci. USA published online 15 May 2009, doi: 10.1073/pnas.0903860106: N7 G; O4 U% Z' f" V( j6 P% S
88.
Gonzalez F et al., Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector, Proc. Natl. Acad. Sci. USA published online 19 May 2009, doi: 10.1073/pnas.0901471106
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Wilson KD et al., MicroRNA profiling of human-induced pluripotent stem cells, Stem Cells and Development 18, 749-758. June 2009, doi: 10.1089/scd.2008.0247