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9 Y7 p+ ^3 S* @1. Cell Stem Cell. 2009 Jun 5;4(6):466-7.! M* ~. A7 M  @: l

. E; p6 x& E0 P) gGlioma stem cells: better flat than round.
, [% ]0 k: r+ ], ~4 y/ h6 GWoolard K, Fine HA.
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Neuro-Oncology Branch, National Cancer Institute, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
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/ Q; {/ n4 M2 G1 M9 r, @# |Cell Stem Cell. 2009 Jun 5;4(6):568-80. 0 ^; O8 Y) J$ E  c" T

" Y6 x, K' ~+ V  E# a1 h1 J6 s) wAbstract
" j. d  h. ?' T  sGlioma-initiating cells/glioma stem cells (GIC/GSCs) are grown in vitro using a cumbersome and inefficient spheroid assay. In this issue of Cell Stem Cell, Pollard and coworkers present a protocol for the efficient derivation of GIC/GSC lines that may greatly improve the isolation and the potential clinical application of these cells.+ E5 T) T4 F% W) P4 y4 a8 ]* A

+ p- w# c6 `5 J& `! SPMID: 19497271 [PubMed - indexed for MEDLINE]