Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a

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Hierarchical Maintenance of MLL Myeloid Leukemia6 q+ ~  m; _; J9 B8 Q
Stem Cells Employs a Transcriptional Program
5 \) g+ I0 ]7 G0 J9 y7 {% yShared with Embryonic Rather Than Adult Stem Cells
" [# U6 w9 T$ c# m3 y3 `1 kTim C.P. Somervaille,1,4 Christina J. Matheny,1 Gary J. Spencer,4 Masayuki Iwasaki,1 John L. Rinn,2 Daniela M. Witten,3+ g. ^9 c' Z. ~0 [/ ?: ?
Howard Y. Chang,2 Sheila A. Shurtleff,5 James R. Downing,5 and Michael L. Cleary1,*7 K8 P" {: c* p2 t
1Department of Pathology/ w, F/ N8 Y( D
2Program in Epithelial Biology
! v$ N% q) y3 i& `' z9 X3Department of Statistics
" V6 N0 y/ j8 G4 \  U- WStanford University, Stanford, CA 94305, USA
' B3 W) q) q% f5 n4 x4Cancer Research UK Leukaemia Biology Group, Paterson Institute for Cancer Research, University of Manchester,
0 q5 m( Z$ m4 i  F& y- U- ~- tManchester M20 4BX, UK
1 o, q; W5 d3 s4 \0 o5Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA& K2 c! t3 `. z
*Correspondence: mcleary@stanford.edu+ X2 Q* }6 m* b* R' _/ l( _. r4 ~, o
DOI 10.1016/j.stem.2008.11.015
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