Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a

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Hierarchical Maintenance of MLL Myeloid Leukemia( P+ C/ ~" m3 Q3 y# u
Stem Cells Employs a Transcriptional Program
3 d9 u' S7 m! IShared with Embryonic Rather Than Adult Stem Cells1 s4 |# w2 g% D, ~5 a$ [
Tim C.P. Somervaille,1,4 Christina J. Matheny,1 Gary J. Spencer,4 Masayuki Iwasaki,1 John L. Rinn,2 Daniela M. Witten,3
, ?( a( A3 H8 s1 g# L* tHoward Y. Chang,2 Sheila A. Shurtleff,5 James R. Downing,5 and Michael L. Cleary1,*+ [) z0 P( `/ {2 u
1Department of Pathology
5 n" J+ v, B: E' x: ?  W. N4 i2Program in Epithelial Biology/ o8 s6 }0 F- M9 K% |
3Department of Statistics
6 X6 ?! V+ G5 |7 D) H5 G2 YStanford University, Stanford, CA 94305, USA
5 b) @$ {8 E/ e) H2 r* A- R4Cancer Research UK Leukaemia Biology Group, Paterson Institute for Cancer Research, University of Manchester,4 E  s" H4 T9 X+ A8 }
Manchester M20 4BX, UK" s3 b( O' c( T+ _8 Q7 B
5Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA) p. V( E& S; p0 e! w/ u7 F" J: f
*Correspondence: mcleary@stanford.edu: l% |% S; m( k7 u. [1 \
DOI 10.1016/j.stem.2008.11.0158 \% |; i# ]6 s& ^0 P

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guoguijie

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tspaulzhao

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pau10

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may21thwlp

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金鹤

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