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Strongly recommend this "old" paper.& [4 Y! g3 r& k" k5 }- f) m
) j" U6 L' ?: ?3 L) K1 ]5 k2 I' B3 v4 Z. a1 l) o3 f) s/ [
A Cup Half Empty or Half Full?6 c$ j; e" h9 x0 j: K3 `" B
George Q. Daley7 Q! D; m7 z: P3 n! `
Abstract,
% r/ W; e. Q9 CWhen first reported 4 years ago, gametogenesis from embryonic stem (ES) cells promised an
) O* E. t6 `8 [+ L' qaccessible in vitro model to facilitate molecular analysis of the germ lineage. Formation of2 V; `* B9 }; V$ Z
primordial germ cells is robust, but terminal gametogenesis remains inefficient and doubts
! @& [$ {5 q$ Y& Q" uabout gamete function persist. Although useful for research, clinical use of ES cell–derived
# U* o' @ a4 s( |7 R5 Ngametes appears a distant prospect. |
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发表于 2009-3-2 10:34
发表于 2010-8-2 16:17
