Cell进展：Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression

轩辕之客

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非编码RNA与P53介导的细胞凋亡：
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0 k9 W  J+ n+ D; I# H. J" ^! k1 SRecord Number: 1065
- A/ i, c% x- f3 gAuthor: A. M. Barsotti and C. Prives
2 m. g3 ?: n1 k5 @8 N$ _Year: 2010
2 Z: o5 N; p7 q0 K. K# c3 gTitle: Noncoding RNAs: The Missing "Linc" in p53-Mediated Repression
# B. X' W- B, t4 s+ ^" jJournal: Cell
& Z. G7 l' v; J; T0 D, nVolume: 142
$ q3 h7 N8 W8 T2 B  a, _) m+ J4 O, jIssue: 3
  P( M6 V. x/ Q* ]) `% j% sPages: 358-360
3 \- N  C& p5 F  w2 ~( GEpub Date: 2010/08/10$ J. z  A. S) i6 j* P* _
Date: Aug 6
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Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression+ U' }! ?  j* m* T4 j

% V# u1 J1 P( U0 r9 tThe tumor suppressor protein p53 coordinates the cellular response to stress through regulationof gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a newplayer in p53-mediated repression of genes involved in apoptosis.