Cell进展：Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression

轩辕之客

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# b; D( f& B" J, g' g6 O非编码RNA与P53介导的细胞凋亡：5 f! q# r& b3 D9 @& A! {, g- Y& Q
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Record Number: 1065
- h% q2 W+ R& O( q/ \Author: A. M. Barsotti and C. Prives
6 Z* S+ ?: V1 eYear: 20102 M+ P' |. a1 l8 B) |: ~
Title: Noncoding RNAs: The Missing "Linc" in p53-Mediated Repression3 ~. b8 a" v+ H
Journal: Cell8 D4 a! q2 |4 ^8 m$ i
Volume: 142- v. ~" e% O! B6 ]. P0 n
Issue: 3
* p- P, N; \4 m4 o' G+ B# vPages: 358-3609 S5 b: O+ p1 p# n' }/ o
Epub Date: 2010/08/10
! n5 L. D4 p* ~& e, d- n! x1 m5 RDate: Aug 6
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Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression
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The tumor suppressor protein p53 coordinates the cellular response to stress through regulationof gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a newplayer in p53-mediated repression of genes involved in apoptosis.