日本利用干细胞疗法治愈高位截瘫猴子

痞子的烟头

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胚胎干细胞何时能应用到临床，最初始的细胞不表达组织相容性复合物，但异体由于生物发育模式不同，在体内成熟过程，抗原会被识别，难免会产生免疫排斥；IPS先不说诱导方法，单是基因整合就有很大的危险性；现在市场临床治疗可以用的还只有成体干细胞，先不说安全性有效性如何，起码不会有危险；/ z& ?: O7 F- O* Y# N
期待下一步结果……. _* J7 `6 R9 v2 I3 F
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qingshui1985

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英文稿件：" [1 }" J( |6 a$ p6 j& w" \, V3 K
A young marmoset is carried by its father at the Amneville zoo, eastern France, June 2010. Japanese researchers said Wednesday they had used stem cells to restore partial mobility in a small marmoset that had been paralysed from the neck down by a spinal injury.
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Japanese researchers said Wednesday they had used stem cells to restore partial mobility in a small monkey that had been paralysed from the neck down by a spinal injury.
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! ~# V2 j5 P! Y7 D, `5 x; M, W"It is the world's first case in which a small-size primate recovered from a spinal injury using stem cells," professor Hideyuki Okano of Tokyo's Keio University told AFP.
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Okano's research team, which earlier helped a mouse recover its mobility in a similar treatment, injected so-called induced pluripotent stem (iPS) cells into a paralysed marmoset, he said.. v& k/ i, L' n4 R6 x
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The team planted four types of genes into human skin cells to create the iPS cells, according to Kyodo News.( k% u! _4 y) B1 }& p8 p
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The injection was given on the ninth day after the injury, considered the most effective timing, and the monkey started to move its limbs again within two to three weeks, Okano said.
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"After six weeks, the animal had recovered to the level where it was jumping around," he told AFP. "It was very close to the normal level."
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7 ^8 G+ _0 a4 W+ _) N- J! I"Its gripping strength on the forefeet also recovered to up to 80 percent."
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8 C2 F6 L: |5 L# }4 [. X* ^Okano called the research project a major stride to pave the way for a similar medical technique to be used on humans.# i. B# f+ o& B( ~
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Scientists say the use of human embryonic stem cells as a treatment for cancer and other diseases holds great promise, but the process has drawn fire from religious conservatives and others who oppose it.* q6 L) Q4 c1 m5 o+ O( m

2 n9 O# k- C  U  w0 x2 i5 UEmbryonic stem cell research is controversial because human embryos are destroyed in order to obtain the cells capable of developing into almost every tissue of the body.
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