PDF电子书：[统计遗传学手册].Handbook.of.Statistical.Genetics.pdf

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! n0 {7 l" b' O  e. A分享[统计遗传学手册].Handbook.of.Statistical.Genetics.pdf3 O/ E8 I& {; y+ X
By David J. Balding, Martin Bishop, Chris Cannings! l9 q) `: e) }/ [: y2 l& g8 @* ?
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目录: 2 U8 v, e0 T, s4 x  S3 R' q8 {, j7 m
Contents2 G# v, f7 U, E& W( E1 a
VOLUME 1. f2 v8 C) F. D- P; d
Colour plates appear between pages 220 and 221, and pages 364 and 365
8 m. Y) k( r5 M$ jList of Contributors xxix
5 r2 @% O1 E8 ~7 |& Z) p" |Editor’s Preface to the Third Edition xxxv
) Z& }- J" u+ q9 Z* U; X( S: lGlossary of Terms xxxvii
% B  r3 s3 y# I% l  e1 o0 K; ?Abbreviations and Acronyms xlix1 ~& O% d7 S8 I  \% p, L
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Part 1 GENOMES 1: y+ O* m6 U8 ^% f: n! f
1 Chromosome Maps 3# [! q. }* ]; x0 I5 a2 ~
2 Statistical Significance in Biological Sequence Comparison 40: Q1 e- c" u7 B
3 Bayesian Methods in Biological Sequence Analysis 67
# X2 u) \& U) |4 Statistical Approaches in Eukaryotic Gene Prediction 97
( t; ^3 I$ k+ w3 d- T5 Comparative Genomics 160
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Part 2 BEYOND THE GENOME 201
9 ?* ^, l  ?, h. Q6 Analysis of Microarray Gene Expression Data 203, B2 v8 C! h3 ~: W$ Q! z9 g4 I
7 Statistical Inference for Microarray Studies 231
0 M; v) t% U& X$ f( _" w& {8 Bayesian Methods for Microarray Data 267) O  k# `. {) B1 _
9 Inferring Causal Associations between Genes and Disease via the Mapping of Expression Quantitative Trait Loci 296
" {) @: j! P4 v: s/ C) S/ J10 Protein Structure Prediction 327/ b% m0 _% w( v5 R2 W4 u
11 Statistical Techniques in Metabolic Profiling 347
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Part 3 EVOLUTIONARY GENETICS 3755 F7 x% f& \4 X1 D9 u7 g& C
12 Adaptive Molecular Evolution 377: Y! P' I" y  A. b( g4 P
13 Genome Evolution 407
; U+ c( {0 K5 L) b14 Probabilistic Models for the Study of Protein Evolution 439" h) S1 a+ V# w8 u5 S& J
15 Application of the Likelihood Function in Phylogenetic Analysis 460
# h" R: ^- Q# Q$ R5 X5 ?. T16 Phylogenetics: Parsimony, Networks, and Distance Methods 4892 u. d& M7 L* u, y5 e) ^# w8 R
17 Evolutionary Quantitative Genetics 5332 K/ V  }, x- x' H3 f
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Part 4 ANIMAL AND PLANT BREEDING 587
5 H3 C! {* i* I. z& _18 Quantitative Trait Loci in Inbred Lines 589
* \& R7 k' t; u( x19 Mapping Quantitative Trait Loci in Outbred Pedigrees 623
! W/ i3 h4 S( F8 X: g20 Inferences from Mixed Models in Quantitative Genetics 678
/ {) T+ k2 t, q9 m9 M21 Marker-assisted Selection and Introgression 718- e. R! @1 k$ x+ {' d

9 A  u( @( L1 ~9 J. ?0 `VOLUME 2( K! X% U) C  A. }2 a8 J
List of Contributors xxix1 K: k! N& ]5 Q5 o( a- g1 x
Editor’s Preface to the Third Edition xxxv. a3 n6 O) e7 U  l
Glossary of Terms xxxvii
; y8 P" j4 A$ [! G0 d0 O, |9 E) ~Abbreviations and Acronyms xlix
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4 b) c2 v- S2 R0 j, cPart 5 POPULATION GENETICS 753
5 b, p) x7 x- G: F9 h& E& v7 }22 Mathematical Models in Population Genetics 755
( `! F3 ~8 q$ C: t23 Inference, Simulation and Enumeration of Genealogies 7819 b' S6 Z- d% W! K# X
24 Graphical Models in Genetics 8086 p: D# S- u9 [: _" F
25 Coalescent Theory 843( g% q- I7 p3 i9 }; }5 k0 Z4 ^
26 Inference Under the Coalescent 878
$ q" }2 F. B' y& l! K27 Linkage Disequilibrium, Recombination and Selection 909. D+ d* _! J& `; T
28 Inferences from Spatial Population Genetics 945( E6 ~, D# _( R, q0 B
29 Analysis of Population Subdivision 980
* N9 ^! z, t6 s30 Conservation Genetics 10215 e9 A# a( y3 T6 ]; _
31 Human Genetic Diversity and its History 1067
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9 y% L2 g0 f. ^6 n1 \! QPart 6 GENETIC EPIDEMIOLOGY 1109
0 L  ~; j* R2 p: H- U8 \32 Epidemiology and Genetic Epidemiology 1111+ B  y# K( u8 g: m, I
33 Linkage Analysis 1141
' r  g  G+ t7 @) {+ u34 Non-parametric Linkage 11689 P( ^; w( V7 M: R' ^  M, |
35 Population Admixture and Stratification in Genetic Epidemiology 1190
" X; V/ \. R5 f36 Population Association 1216
% j3 P- p2 S' K% j37 Whole Genome Association 12382 {& q* c# O  U/ R4 [5 I
38 Family-based Association 1264
! l9 i" j6 P' X7 g' T% V  x* j  j39 Cancer Genetics 1286
# I( E$ n% F/ K( X3 n0 |40 Epigenetics 1301, @1 O9 D# m: n$ ^) `
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Part 7 SOCIAL AND ETHICAL ASPECTS 1323
: H1 T9 k" q+ l6 k4 J- c1 b41 Ethics Issues in Statistical Genetics 1325
9 J- h  m$ P! S* v42 Insurance 1346. k" p+ A& K$ {* C( R% b
43 Forensics 1368
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