PDF电子书：[统计遗传学手册].Handbook.of.Statistical.Genetics.pdf

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分享[统计遗传学手册].Handbook.of.Statistical.Genetics.pdf
, T) m7 {. }1 T. r; \By David J. Balding, Martin Bishop, Chris Cannings
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目录: 8 E3 j3 X$ m; L4 c7 y; Z
Contents9 N: V( l9 a! P
VOLUME 12 f, j) ~8 |, [
Colour plates appear between pages 220 and 221, and pages 364 and 365
4 f+ k; f; T/ hList of Contributors xxix
' W1 ~# T) y: sEditor’s Preface to the Third Edition xxxv
0 W$ z  P0 m+ z# j' L+ wGlossary of Terms xxxvii# }' c" o+ f; [/ q9 N, L
Abbreviations and Acronyms xlix
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Part 1 GENOMES 1
! K" X8 k' L. K- o! l1 Chromosome Maps 3% A- N; u3 C1 h
2 Statistical Significance in Biological Sequence Comparison 40/ J; T7 m7 b+ I* D6 v
3 Bayesian Methods in Biological Sequence Analysis 67
% F3 P8 V# L+ v2 V/ }2 ]' K1 L- C+ W4 Statistical Approaches in Eukaryotic Gene Prediction 97' ]  a$ ]$ w4 ]; G# e# c
5 Comparative Genomics 160
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Part 2 BEYOND THE GENOME 201
! o7 E4 c: W" W  i1 s6 Analysis of Microarray Gene Expression Data 203
: N% F" s4 R0 O3 F) w7 Statistical Inference for Microarray Studies 231+ V9 G: O& Q7 y# F1 ^
8 Bayesian Methods for Microarray Data 267* z/ r7 s" B. \1 o
9 Inferring Causal Associations between Genes and Disease via the Mapping of Expression Quantitative Trait Loci 296; m; q. o5 V0 R
10 Protein Structure Prediction 327
5 F* f/ [( F  d. T" a2 L11 Statistical Techniques in Metabolic Profiling 347; Z4 U1 b, z1 l  N: a, H
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Part 3 EVOLUTIONARY GENETICS 375
: `4 c/ f: l( f/ X4 Z! S12 Adaptive Molecular Evolution 377) W$ e+ x( x6 b3 `8 s0 L; B2 |
13 Genome Evolution 407: [' `3 i; R/ K9 e+ {
14 Probabilistic Models for the Study of Protein Evolution 439
& b  L, B) s1 n5 v15 Application of the Likelihood Function in Phylogenetic Analysis 460
& Y2 V8 I  f2 G9 v16 Phylogenetics: Parsimony, Networks, and Distance Methods 489
' l% D, U8 n. B( }+ N17 Evolutionary Quantitative Genetics 533
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Part 4 ANIMAL AND PLANT BREEDING 587. U& x8 d+ F: m! c* |+ k
18 Quantitative Trait Loci in Inbred Lines 589
3 Y1 K' g! W4 ~* Z19 Mapping Quantitative Trait Loci in Outbred Pedigrees 623
  @( A  N8 p# x20 Inferences from Mixed Models in Quantitative Genetics 678
4 e6 }) }' t0 I3 B21 Marker-assisted Selection and Introgression 718
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8 Q* J# D' F5 g; u1 uVOLUME 2. a& ^& y3 N5 ?6 ]3 {1 T/ j& s" L3 H
List of Contributors xxix
; C$ ^5 g1 [$ r7 @. I* o' @Editor’s Preface to the Third Edition xxxv
, }1 n7 M) B' ^! QGlossary of Terms xxxvii
# Q, j: L8 O+ H, J; r4 aAbbreviations and Acronyms xlix* P2 O, `/ ?$ y$ W

0 e/ m! R( i# ^2 [: jPart 5 POPULATION GENETICS 753
& }8 c. c4 @2 ?0 F. j22 Mathematical Models in Population Genetics 755$ T; n8 D. h1 J
23 Inference, Simulation and Enumeration of Genealogies 781
2 g% d9 x" I$ F0 d5 x5 m24 Graphical Models in Genetics 808. Y. d: l  X3 y" ~
25 Coalescent Theory 843$ q4 D* Y+ I! W- Q, n$ t( S
26 Inference Under the Coalescent 878
- Z( j, l2 k% ?- k( k4 O27 Linkage Disequilibrium, Recombination and Selection 9097 X4 q8 F2 `: Z4 T. e" z+ I7 Z2 ]
28 Inferences from Spatial Population Genetics 945- x; p% v& }2 S/ l/ e& ]3 F0 o9 b
29 Analysis of Population Subdivision 9803 Z3 W% F( D) o; A$ L
30 Conservation Genetics 1021
1 T4 q' L/ h" D& g/ W6 ~$ K/ N31 Human Genetic Diversity and its History 1067$ u" b+ z9 g! U, I& I" \& V6 L, C# d

% H1 t- a) e+ a9 N/ g1 h) h% ~Part 6 GENETIC EPIDEMIOLOGY 1109+ W# Y( @. s: G! h2 l
32 Epidemiology and Genetic Epidemiology 11117 d. k9 B! V7 a  E0 u, K2 k( J; U
33 Linkage Analysis 1141
+ u4 j$ z+ ]! Y. {34 Non-parametric Linkage 11680 t9 c& u6 P* [# L5 ^+ {: i8 w
35 Population Admixture and Stratification in Genetic Epidemiology 1190
( F& B3 z0 ]9 R/ X. A8 |36 Population Association 12161 }+ ?& J: _4 M' B. T) _, [3 C
37 Whole Genome Association 1238
7 {- K2 i+ x- s0 I38 Family-based Association 1264
! [  [$ S4 z  }4 E! b39 Cancer Genetics 1286, {+ N% E5 c) u
40 Epigenetics 1301! j1 }& P( A! O/ J: W; f  [. l
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Part 7 SOCIAL AND ETHICAL ASPECTS 1323/ `: ?4 k! h1 q3 Y
41 Ethics Issues in Statistical Genetics 1325
* h- k6 D* Q" F3 P, ~! T" C. F7 C42 Insurance 1346: u2 g/ U& ]1 h* S6 R4 V2 E
43 Forensics 1368
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