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第一篇:
+ r" F) O( D8 t" Y* Vhttp://www.ncbi.nlm.nih.gov/pubmed/21393998
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$ U A/ M( x$ Z1 i' H9 fCell Cycle. 2011 Apr 1;10(7):1015-6. Epub 2011 Apr 1.
* {* u" h' c. u3 W( h2 _mTOR upregulation of glycolytic enzymes promotes tumor development.
- n2 ^; z' K9 ~$ ]: ~Zha X, Sun Q, Zhang H.
$ a0 L/ m ], R% o) m* CAnhui Medical University; Hefei, China.* R; {. I5 i1 k: M' y' G+ ^
' K- n6 c/ N& G- f: I- H- o第二篇:2 ]. h3 ?4 s( U+ Y* y; i
http://www.pnas.org/content/108/10/4129.full.pdf+html
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; j4 ^6 R S6 z9 D) [Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
- k1 }' U; x; K6 N& E# [6 cPNAS 2011 108 (10) 4129-4134; published ahead of print February 15, 2011, . w- n7 K) {3 q8 V
4 H& P& ?0 x2 o( T) F第三篇:
' }9 N" `1 H: fhttp://www.nature.com/ncb/journal/v13/n3/abs/ncb2168.html( g" A) R) i% j! T- @ _+ B- x/ q
; L+ G% J, S: ^9 I' Y6 W4 [Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1. ~( c) w4 L0 P/ n; q. `6 K+ l
Min Zheng,1 Yan-Hai Wang,1 Xiao-Nan Wu,1 Su-Qin Wu,1 Bao-Ju Lu,2 Meng-Qiu Dong,2 Hongbing Zhang,3 Peiqing Sun,4 Sheng-Cai Lin,1 Kun-Liang Guan5 & Jiahuai Han1
# `; {0 Q9 f+ I/ E/ {0 DAffiliationsContributionsCorresponding author Journal name:# h5 { u. o1 E0 N& E1 g) p
Nature Cell Biology Volume:13,Pages:263–272Year published 2011)DOI:doi:10.1038/ncb2168
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第四篇:
3 a! ]* ]; |3 c/ v3 G5 Jhttp://cancerres.aacrjournals.org/content/71/1/13.abstract
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0 g3 W* J& K& X! g" u% ELactate Dehydrogenase B Is Critical for Hyperactive mTOR-Mediated Tumorigenesis
; Q! y( ~5 r2 k4 [; h8 eXiaojun Zha1, Fang Wang1, Ying Wang1, Shaozong He1, Yanling Jing1, Xueyan Wu2, and Hongbing Zhang14 S9 V- K0 G& m
1 L) }# S0 u: d1 i第五篇:
3 J+ v0 y+ G" s4 s5 Khttp://gut.bmj.com/content/59/12/1687.full.pdf1 Z3 g. \4 v( F& M
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Paper: Golgi protein 73 (GOLPH2) is a valuable serum marker for hepatocellular carcinoma
3 m6 n4 m- N1 W& e3 Z- Q! s! y4 _Yilei Mao, Huayu Yang, Haifeng Xu, Xin Lu, Xinting Sang, Shunda Du, Haitao Zhao, Wang Chen, Yiyao Xu, Tianyi Chi, Zhiying Yang, Jianqiang Cai, Hui Li, Jianguo Chen, Shouxian Zhong, Smruti R Mohanti, Reynold Lopez-Soler, J Michael Millis, Jiefu Huang, Hongbing Zhang Gut 2010;59:1687-1693 Published Online First: 28 September 2010 8 O9 x) D! K5 [. G2 J+ c
9 ^% Y% Z' g: M+ R4 g+ n第六篇:
' R0 S: U! x! Chttp://www.nature.com/emboj/journal/v29/n17/pdf/emboj2010166a.pdf+ n3 e+ x& \; y/ _
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The EMBO Journal (2010) 29, 2994 - 3006 doi:10.1038/emboj.2010.166
/ b. e" m# l2 \/ O6 D# WPublished online: 23 July 2010
1 f9 N% t$ H0 x7 H/ `( n6 }S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response |
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