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- 积分
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Cells can communicate with each other through the
; P* h$ e$ O; ]& e$ H' _7 ]) ^secretion of cytokines, small (8–30 kDa) soluble proteins.& s6 V! q- [' N* I9 X
To date, roughly 20 cytokines have been identified. Upon/ D! z( [6 q$ Z" x; K. ^
binding their cognate receptors, receptor-associated Janus
; X5 I! Z8 v1 |5 [$ u/ U6 nKinases (JAKS) phosphorylate tyrosine residues of the
6 a# E# Q! k- b+ m2 Vligand-bound receptors, as well as interacting Signal+ |& v% k! }9 P; Q5 Z+ ^; q
Transducers and Activators of Transcription (STATs).Tyrosine phosphorylated STATs form homodimers, shuttle
: `0 p6 T1 Y$ Qto the nucleus and participate in transcriptional regulation
; f1 n- k: s; M0 kof a variety of genes
{2 ^5 n) q7 H- r( f% {# k0 q. b% x, @( l& ]
我标记的这一句,是什么意思呢 ,为什么我连语法结构都分析不过来呢,总感觉少了点什么!希望热心人给予解答! |
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