Duesberg博士提出新的癌症成因观点——癌症是新进化寄生物种

mcherry.f

If such a proposal does not want only to be a concept, more evidence is required. BTW, Peter Duesberg is well known for the idea that HIV is not the pathogenic origin of AIDS and he persists that pharmaceuticals exaggerate the role of HIV in AIDS. And I also do not agree that he was one of the several scientists who first cloned oncogenes. If so, please give the citation.

mcherry.f

回复 marrowstem 的帖子0 O$ k. d, U7 H; {$ V. T
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As a "版主", I think you should be responsible for what you post here. This time, I can give the references for what you said here, but I really what everyone should be in charge of his points, not just for attracting eyeballs. " O2 U) r% |/ `0 Q" F0 }4 N

( b0 f/ b$ E  o9 dIn 1970, Peter Duesberg and colleagues first recognized the differences on RNA sequence between transformed RSV and transformed deficient strains (1). To be honestly, this paper can be viewed as a breakthrough initiating oncogene cloning, but no one in cancer studies will give the credit of first oncogene cloning, v-src, to Peter Duesberg. What accepted by most people in this field is that the first oncogene cloning work was performed by Drs. Bishop and Varmus(2)(3), and that's also the reason why they awarded the Nobel Prize.  " r$ C" s6 A1 _4 [7 k
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I do not what to offend you, but what you posted here was just transferred from other biological news website ("生物通" this time), why not give the resource of this post?; m- p7 @8 R$ b  e4 z
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For Peter Duesberg, it's not the questioning style which makes me against him. Actually, Peter Duesberg just persists that HIV is a harmless passenger virus, not the causing pathogen for AIDS, but he can never give any evidence to support it. What most annoying is, as the advisory member for South African against AIDS, due to his influences, the government did not provide anti-retroviral drugs to patients in a timely manner which is thought to be responsible for hundreds of thousands of preventable AIDS death and HIV infection.
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5 A1 K5 R' v+ F' h9 hAs a scientist, especially in biomedical fields, what lets Peter Duesberg unacceptable is not the "novel" ideas, but his flibbertigibbet-style in science. ( s. I, T" ~4 Z

- ~% c; _- j: VReferences:
/ Y7 X6 h0 J) i, G$ u(1) Duesberg, P. H. & Vogt, P. K. Differences between the ribonucleic acids of transforming and nontransforming avian tumor viruses. Proc. Natl Acad. Sci. USA 67, 1673–1680 (1970).
" y, Y5 u1 I& v. u+ I/ g7 F3 d(2) Stehelin, D., Varmus, H. E., Bishop, J. M. & Vogt, P. K. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260, 170–173 (1976).2 D2 T; c4 R9 O# r  v0 Q# T6 Z: t
(3) Spector, D. H., Varmus, H. E. & Bishop, J. M. Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc. Natl. Acad. Sci. USA 75, 4102–4106 (1978).

mcherry.f

回复 marrowstem 的帖子- d2 v6 Y( L- Z& w  f) K7 Q

! u, M0 v: O8 hIf so, where should we put the positions of Bob Weinberg, Mariano Barbacid, Micheal Wigler and Bert Vogelstein?
9 e! o: [( r' O0 ^! z4 \9 h0 @) AThe contributions of these scientists make up half of the contents in cancer biology, especially Weinberg and Vogelstein.
2 C  U! d8 ]7 t; rIf you have read the article in PNAS 1970 by Duesberg, you will notice that there is only a electrophoretic differences, even not other supports.
! q. g0 f, Y; T6 a: D/ g8 xActually Peter Duesberg is a "famous" person, but notorious for what he did, due to the lives of thousands of people. ; v! \  l3 H" P* w& M
The motto of KI is to improve human health, they will never give the prize to such a guy.
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& k/ |% r4 G/ y8 e6 |' N0 F& ~7 P) v0 ]Sorry to say this.