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- 积分
- 164
- 威望
- 164
- 包包
- 1030
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histone H3
! M$ A" p$ Z# ~8 e0 q3 N" d3 xmethylation at lysine 9 is associated with heterochromatin and+ E, n, ]( [# Y0 o
gene silencing, while histone H3 at lysine 4 or 27 is associated. L( i- Y8 o' ?% @* ?
with transcriptional activation.
% s. p, t5 y, E" \/ I2 b4 g, P) M1 h
Each lysine residue may be v+ ?" M+ d$ J( V
methylated in the form of mono-, di-, or tri-methylation, adding
0 Y2 G! J( y0 O/ Y! Uenormous complexity. Deciphering histone tail modifications
& X( O+ w- c* k4 s& X/ @and defining a potential “histone code” controlling gene expression
) L! r4 w/ S1 t/ T4 i z% Z% \: Mrepresents an emerging field of epigenetic research 。
- n6 m( |# u2 t. cWhether the potential histone code is modifiable by environmental
4 @* C$ a# |! K1 [9 B* u6 t: gexposures, similar toDNAmethylation patterns, remains$ B3 c I h* M8 ]8 Z
to be determined.
f5 v. _! `: m) v可以的话请把汉语写下来,谢谢。里面有些术语我都不知道翻成什么。 |
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