求关于小分子在iPSCs诱导过程中的作用有关文献

genedu

各位大虾，谁手里有关于替代OCT4，SOX2，Klf4，c-Myc这四个因子以及其他诱导因子的小分子的文献？小弟拜谢了
- |3 N4 @9 j0 c+ i+ j如果有哪位神人实际操作过的，请告知小分子名称及其用量。
7 Y  U0 ?3 ~* t- j再次拜谢

cellbuddies

可以参考丁盛的文章，给你一个文章列表
1 D5 W& z3 J; L5 I8 aGeneration of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors0 A' T8 R. }% a& E# l+ \% ^
Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming
8 a3 `% w% e) `8 vA chemical platform for improved induction of human iPSCs-supplemental methods and data0 f' n6 O8 i( V. U- ~: w+ C
还有University of Cambridge的Austin Smiths: D3 `# k& P- n  P
Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

cellbuddies

full text

cellbuddies

MEK inhibitor PD0325901 (Sigma, 0.5 μM)
4 T( R; _0 c; c+ W5 y' @3 ~ALK5 inhibitor A-83-01 (Tocris Bioscience, 0.5 μM)
2 W1 h/ W- L% k& A) HGSK3β inhibitor CHIR99021 (BioVision, 3 μM)
1 F! g) u2 \- O0 `* {( m! d; k挺贵的，大概5000大洋

genedu

回复 cellbuddies 的帖子# A- M# a# a% s' P/ T7 A8 _" F
5 O4 g' q1 V# `! |
真是太感谢了。临帖涕零，不知所言