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从权威杂志 blood, cancer research, cancer cell, cell ,cell stem cell, cell research, stem cells, PNAS, nature 系列等收集了74篇研究性论文,与大家分享。, E0 S& H+ }/ ?& ^* r9 Z( {
1 S2 I9 l5 p8 v% J! cJiang, X. 2010 Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
/ H/ k+ H+ P$ V( gBlood
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Peng, C. 2010 PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
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Sengupta, A. 2010 Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.& M/ T% R% r& e
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/ q6 R4 ]9 Q- ^1 x* k; DSmith, A. C. 2010 High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.: l4 x8 y5 s, q% C9 V; G
Blood
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+ G. x' n5 C! n+ p5 {1 }Taussig, D. C. 2010 Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
- O2 X2 d" C' Z$ oBlood
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Chen, R. 2010 A hierarchy of self-renewing tumor-initiating cell types in glioblastoma./ G- s, n3 c+ a4 U4 G e# w
Cancer Cell1 O( _. Y6 R; `6 m8 m% s; H3 d
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Yeung, J. 2010 β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.
( ]0 L5 e( U0 iCancer Cell4 }7 j- U$ `0 ?
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Zhang, B. 2010 Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
. g0 A5 ~' U# [; _' _/ kCancer Cell
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Biernacki, M. A. 2010 Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.
' X) |9 D; n; R+ KCancer Res
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Bonnefoix, T. 2010 Cancer stem cells promote tumor vascular development--letter.5 v# X, ?6 P' W% c* Q1 q) |
Cancer Res( w: n: H0 |: O) e3 J1 Y; y
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Cammareri, P. 2010 Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.; m x$ {( Q! D' q0 i
Cancer Res
% b7 t# W7 S! M, r i/ s4 F" c" _$ n4 [添加到文献库: 04 Mar 2012上次更新日期: 04 Mar 20120 }( R& b+ o `* B0 i( B) f
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% y k" F K- y1 wChiou, S. H. 2010 Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.
0 T( n/ \5 C! u. b+ k0 w9 eCancer Res
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4 A" v3 C, D9 D4 ? g- DDeka, J. 2010 Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.
) w/ B$ d3 D. l, ]5 Q8 |- QCancer Res
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, j4 }5 s1 ~2 }8 xHarrison, H. 2010 Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. m# b) J9 r$ R; h. X' v5 M
Cancer Res' B1 v. D0 k2 x p$ B
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4 d; D( p+ H2 GHebbard, L. W. 2010 Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.
4 o: R1 l8 H( P& @$ O$ }* J/ ?- ^Cancer Res
6 y( G5 z1 n' D9 I% a8 |7 J2 g( E添加到文献库: 04 Mar 2012上次更新日期: 04 Mar 20127 z" v/ n0 \/ z. ~/ r
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; E4 }# [. W/ ?5 [& LHeld, M. A. 2010 Characterization of melanoma cells capable of propagating tumors from a single cell.9 c* u' i9 V' Q( J+ E( p9 h
Cancer Res8 S; |$ L# N7 Y1 F p
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* }) }. r. f* Y- J7 P; {Jin, Y. 2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.6 H5 k2 ]5 x1 ~# D- U w6 {# Z8 `
Cancer Res
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" Q9 B1 H; I( W2 xJo, M. 2010 Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
2 J2 n# x7 L, w9 S: ICancer Res
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* ?4 o7 L# B. g( x0 `- yJoseph, I. 2010 The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.( u/ L2 [, l+ t7 \4 o: i+ V
Cancer Res$ T# j2 K! X1 q! w( X
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Kemper, K. 2010 The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation.
+ D6 @# {- ^3 L7 ]5 aCancer Res
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Krishnamurthy, S. 2010 Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells.
& {5 T |+ g# k/ @, Q4 zCancer Res
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! G! }+ I; W5 e! l+ o$ U2 r4 b! hLee, J. H. 2010 Pathways of proliferation and antiapoptosis driven in breast cancer stem cells by stem cell protein piwil2.! C k% M1 p/ P" o
Cancer Res
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Levina, V. 2010 Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop.
5 q2 Y( `6 J0 \; ^Cancer Res
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Liao, C. P. 2010 Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells.
% z6 y3 e2 J; W4 L1 P8 C) HCancer Res
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3 w: m2 R" Y$ E% {- W2 c/ I4 ?Liu, M. 2010 The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
1 g* N7 d* M9 d6 l1 f$ q- y+ m% WCancer Res9 U& Q3 ^$ y) K. n( c1 t2 `) L
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Lottaz, C. 2010 Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.
: T+ A0 U0 ~1 A, l: NCancer Res( Z1 I. P3 R1 A/ W1 x7 x
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7 l; B2 k4 X. Z6 vMazzoleni, S. 2010 Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.1 x/ C+ W/ g3 e7 S& o- q
Cancer Res8 z _" Z# @, q1 ~' }
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7 U! V( R7 `* j) u! tOoi, A. T. 2010 Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.- S* d) o: M( I3 ` q: Y5 @
Cancer Res" W% Z. S* N* n! a5 P* ?
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Reiman, J. M. 2010 Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.
" M3 s( p1 ?& GCancer Res
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% P9 W6 @, G4 L b* c4 vSchatton, T. 2010 Modulation of T-cell activation by malignant melanoma initiating cells. @5 K# ~5 s( a+ k" f
Cancer Res# ], Q5 V) |0 V0 B6 E. A: e
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* m: p# S( V, t+ m, r2 q0 p: I$ xSikandar, S. S. 2010 NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.
. @9 @7 T9 f/ O/ {. ]2 ^( YCancer Res; f* H# J( l8 w# F9 T
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Sottoriva, A. 2010 Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.- ^: ?" u% r4 j3 x
Cancer Res
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# |& {; n- K0 c' NSullivan, J. P. 2010 Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling., n9 r" ~7 E8 T+ f5 }
Cancer Res
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/ Z' s* I) c( w. |1 w. STodaro, M. 2010 Tumorigenic and metastatic activity of human thyroid cancer stem cells.
% X/ C* a T, b5 C$ ?Cancer Res
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8 | P1 E* {1 k5 ]2 `9 HWong, P. 2010 The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression.% {7 } T; L7 r3 E D
Cancer Res
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) t8 g, |* k x5 KYang, X. 2010 Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.
6 J8 i! ?; X3 KCancer Res, o- v6 y! W) y, h
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# H. I0 X7 z. j2 o) f+ UPece, S. 2010 Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.
; o; x1 C G% w9 b5 T: I5 nCell
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Roesch, A. 2010 A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
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Charles, N. 2010 Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells." R' d9 l& Q- B S Y$ l0 o" V
Cell Stem Cell4 U# K$ ^7 v9 y5 R1 f
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" @; q" l/ [; \+ p7 dKikushige, Y. 2010 TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells.0 g& \2 f V. k/ x
Cell Stem Cell' {& X% W' \5 n- Z# I& S/ x
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+ u8 a/ M B* ?& v4 R# `5 hLathia, J. D. 2010 Integrin alpha 6 regulates glioblastoma stem cells.
' Z3 S1 W; F, Y; r3 h( [Cell Stem Cell7 B( q9 P4 b2 W! C$ t
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Ma, S. 2010 miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.
) |# Z% Z# ?3 N9 M% vCell Stem Cell% S( O {: {. m) o& N" o' u. `* |
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" b% P; y8 L! B. a6 qPang, R. 2010 A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer.
# ?8 T6 |# t1 N G2 _7 sCell Stem Cell
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Wurdak, H. 2010 An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
; `+ I/ Z, c7 q6 E! n4 g6 zCell Stem Cell) p) a# e4 O3 ?& j6 i4 N+ F
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9 h2 S5 d3 n; h- V/ b ~. vYang, X. R. 2010 High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.7 |* |7 ~' X5 s$ o/ \
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+ g" X. W) d+ J T3 xYou, H. 2010 Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta.+ p$ e# d# h' g- J" W$ G0 C
Hepatology3 [0 Q4 \( Z& d' f8 _ @+ K, v9 ?; C, g8 L
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Calcagno, A. M. 2010 Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics.- k* Z9 r2 F, f A' _8 `
J Natl Cancer Inst* ?* Z: _# r7 V3 h, a
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- T' [6 B s4 G, g' d! z xTehranchi, R. 2010 Persistent malignant stem cells in del(5q) myelodysplasia in remission.
. ^- w8 i6 A3 z- b2 @N Engl J Med
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! R8 T0 ]) B2 E: s- y+ |Saito, Y. 2010 Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.; }: f. r' K% f- V4 M
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Vermeulen, L. 2010 Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
$ x+ ]7 J% ^* Z, B2 p/ l6 DNat Cell Biol3 Z6 Q1 g) {% d A/ I: Q" E
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Youssef, K. K. 2010 Identification of the cell lineage at the origin of basal cell carcinoma.8 h! f i7 u5 o6 F2 C# T# F9 m, m
Nat Cell Biol" G, f" P3 Z% s. s M+ W2 i
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Clément, V. 2010 Marker-independent identification of glioma-initiating cells.
% ^1 d9 D! y) q0 x9 mNat Methods/ z- B, w2 h2 i
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Boiko, A. D. 2010 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271.
) U( D O. @0 k8 r8 o5 S9 q5 r! ANature
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Naka, K. 2010 TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.
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Fillmore, C. M. 2010 Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. s9 R* D8 C) O8 S |/ e9 }& y; y
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& S4 N' ]" A+ X( q* W u! ^7 k# r! JJ爀猀, M. 2010 Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.1 O- F5 V# u5 Y7 `. v( E. T/ T. r
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Liu, H. 2010 Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models.4 V* c- `# z* ~% S6 S
Proc Natl Acad Sci U S A
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2 v5 b7 ~5 F5 f7 A. \; H# B( jMiyoshi, N. 2010 Defined factors induce reprogramming of gastrointestinal cancer cells.% }# G( L7 l+ E2 @$ F
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% y, N; T: X/ Q) oMizuno, H. 2010 Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.
/ f/ F4 E0 S% h3 s( L, PProc Natl Acad Sci U S A
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Qiu, W. 2010 Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
& R" s& j9 b; ~& K6 r) @/ B# Q* a1 C/ M, ~Proc Natl Acad Sci U S A
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Rouet, V. 2010 Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.
3 e& T% A; ]* bProc Natl Acad Sci U S A* }9 v' Y$ `. G3 n8 G) W
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6 f8 N* P1 K7 s1 \- n' TYeung, T. M. 2010 Cancer stem cells from colorectal cancer-derived cell lines.
7 ] ]4 J4 W1 r8 ?% g7 o0 n9 HProc Natl Acad Sci U S A
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6 @8 F; h4 ^; `& B. j8 s6 l7 aZhang, M. 2010 Selective targeting of radiation-resistant tumor-initiating cells.
6 f& a2 h5 L1 P3 eProc Natl Acad Sci U S A
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7 V# N% o. Q* T+ _. SWang, Y. 2010 The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
. I' S d; M& z+ N8 |( a3 D) ]Science4 U6 K9 [0 Q+ u% c7 i
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. s, p ` r6 Z2 c* gAbou-Kheir, W. G. 2010 Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.+ p$ A! ~' K7 l0 b
Stem Cells
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deCarvalho, A. C. 2010 Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo.
7 D; |$ T7 V( RStem Cells4 e+ \: n& i7 f! h* ~% F
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Hovinga, K. E. 2010 Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.
' v- {1 x3 T0 LStem Cells. b. B7 P% l: g y
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Hurt, E. M. 2010 Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.$ o. o1 s" {; |4 Q4 [
Stem Cells
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Naka, N. 2010 Synovial sarcoma is a stem cell malignancy.- ~( ], Z: ~ D& H: f1 n7 T
Stem Cells
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x" A1 U! k+ N7 ~( n# XSajithlal, G. B. 2010 Permanently blocked stem cells derived from breast cancer cell lines.
0 k) Y, d- q: @& {1 t2 yStem Cells% a; o& E; k8 N) }2 b2 L: }
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Stuelten, C. H. 2010 Complex display of putative tumor stem cell markers in the NCI60 tumor cell line panel.
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Sunayama, J. 2010 Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.) K0 _# n( }2 E/ X2 v& W
Stem Cells
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0 ^3 P4 Z# P8 N6 o) q; [+ L1 eWang, J. 2010 Notch promotes radioresistance of glioma stem cells.
( e0 A$ p& e& G4 iStem Cells
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1 `- O; W" k0 l. m# lWatanabe, K. 2010 Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.
; T# a) |2 E+ \" t* G0 a* JStem Cells
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