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从权威杂志 blood, cancer research, cancer cell, cell ,cell stem cell, cell research, stem cells, PNAS, nature 系列等收集了74篇研究性论文,与大家分享。# m4 z" ?- K# Z
. i) v3 ]. j0 a6 `Jiang, X. 2010 Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
# B( ]6 R& ]2 E$ SBlood( Q/ ^ U9 u% F- k
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Peng, C. 2010 PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice., g7 M; y( p& B, L+ R' z
Blood
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Sengupta, A. 2010 Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.
6 C) F! v* o- [/ w$ H5 LBlood( U# J) _6 y- ^9 W2 z0 f% H
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Smith, A. C. 2010 High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.5 Y, _, Q0 j3 b2 p! g, f
Blood9 ]9 @- `& g2 c. H
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Taussig, D. C. 2010 Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
$ h# }: @* l5 T6 h; s! hBlood
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+ K9 [; S8 R) F- VChen, R. 2010 A hierarchy of self-renewing tumor-initiating cell types in glioblastoma." v6 C4 r2 H3 n/ N: E r; v' U6 ^" L
Cancer Cell3 B8 c: |* }* P# D( h
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Yeung, J. 2010 β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.% Q+ e& ^" W! r. F: v4 V
Cancer Cell) Z3 x4 g! v0 b! R+ t# J& |
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5 E& P; g) X) d8 DZhang, B. 2010 Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.; l4 ~! q3 y6 ~: A; j2 h1 m6 @# r
Cancer Cell, C' D. F! N, g
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6 O7 X7 R7 B0 ~. L/ W# kBiernacki, M. A. 2010 Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.$ W3 ]" j! l5 V
Cancer Res* E) ?; U9 I k2 |! Z
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Bonnefoix, T. 2010 Cancer stem cells promote tumor vascular development--letter.6 u9 f/ U+ F1 [3 I
Cancer Res
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- t2 Y+ R; o" t( M% ?Cammareri, P. 2010 Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.7 I' ^' L+ ]$ \) x( }
Cancer Res
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Chiou, S. H. 2010 Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.$ Q* e+ `+ ]* n6 n0 I6 o; f$ W4 `* S
Cancer Res7 x( t2 ~- p3 O2 L2 h
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Deka, J. 2010 Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.4 z9 ?. K5 g6 h5 _
Cancer Res/ n, Z2 }+ B/ d, q
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Harrison, H. 2010 Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.$ X& ]( s/ |" w' f; Z9 P* [% E
Cancer Res
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Hebbard, L. W. 2010 Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.
; v6 R+ n5 o- a* K8 Q2 i' WCancer Res0 |( s) i4 U+ L% J& g
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5 L, w, R% S) z9 Z. y# FHeld, M. A. 2010 Characterization of melanoma cells capable of propagating tumors from a single cell.' n' ?( v7 i, h# z( |
Cancer Res& ` D X n. c4 l; k: X
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6 P2 j) k: f2 Y8 O7 C0 x. SJin, Y. 2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
) c" X! q+ ^; I' w$ H: l) BCancer Res+ q; K) y# x! W$ U+ K
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9 o8 o- \, e d$ XJo, M. 2010 Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
{& T$ W" V# l, F1 ^1 _) [4 L( DCancer Res
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Joseph, I. 2010 The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.4 ~7 Y; [+ b% l
Cancer Res
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Kemper, K. 2010 The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation.$ G7 F9 d5 J- r+ Y* Q6 ?3 b
Cancer Res
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4 c+ N0 x3 \" d! VKrishnamurthy, S. 2010 Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells.* {8 H2 ^" V, Z6 r u! J, R
Cancer Res
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Lee, J. H. 2010 Pathways of proliferation and antiapoptosis driven in breast cancer stem cells by stem cell protein piwil2.% {0 T! r1 ?/ ]- j9 B+ A4 o& w+ Z
Cancer Res8 |& @/ w/ k4 ?. m- U% ~
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Levina, V. 2010 Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop.
2 S9 b l* @# f7 GCancer Res- ^( ~% l) x/ O' m
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Liao, C. P. 2010 Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells.
% O. |* R& X( o$ p" g" _Cancer Res' E* M2 u5 p7 H7 \7 Q
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- n# k) L! e2 l7 v: cLiu, M. 2010 The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.: e! r- P) G3 R+ P" R( m
Cancer Res1 H2 p+ ~) Z- Q0 h" q
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Lottaz, C. 2010 Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.
; x. F# x' i- I/ kCancer Res
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Mazzoleni, S. 2010 Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.7 W* V: f* V4 Z0 V1 L, I1 R
Cancer Res
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Ooi, A. T. 2010 Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.# ^3 @* U. }- D6 a3 L/ X: N
Cancer Res
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Reiman, J. M. 2010 Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.
$ {3 ~! c9 ]! x; }Cancer Res) M+ [6 \ q1 K
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8 L6 I# {7 j+ DSchatton, T. 2010 Modulation of T-cell activation by malignant melanoma initiating cells.9 h4 I( r6 I, }: j& K6 e1 l) i
Cancer Res
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Sikandar, S. S. 2010 NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.9 L% A0 o; t' l1 E( U$ m* J
Cancer Res
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Sottoriva, A. 2010 Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.
f$ a7 [9 c' R* t: N, OCancer Res0 [7 C2 }9 z+ d5 I3 s
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Sullivan, J. P. 2010 Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
% c& Q( L/ m' l: X7 F2 ]0 NCancer Res
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Todaro, M. 2010 Tumorigenic and metastatic activity of human thyroid cancer stem cells.
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! J) n' S" I5 q, pWong, P. 2010 The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression.9 L, s' }7 U$ |( X" Y# x- a
Cancer Res2 _6 z# P' f$ z
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) H$ M( P/ Q1 ]Yang, X. 2010 Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.
* e# |7 m" Y4 M0 O) c8 YCancer Res
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( N6 d; Q7 J5 x7 K7 [* aPece, S. 2010 Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.8 [7 t$ E4 u7 [2 h- o; K6 J6 Q
Cell
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0 u3 q2 z8 n+ JRoesch, A. 2010 A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
" I6 K; o2 ?0 P! B) q: bCell8 T; @' n5 n. _5 Z9 v3 U/ D
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Charles, N. 2010 Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.
( @. d4 `% Y) a5 q- u* `/ ?Cell Stem Cell
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Kikushige, Y. 2010 TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells., g! t' c3 a& p' y1 @5 b
Cell Stem Cell
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: }* e( U$ Z3 V7 [! @Lathia, J. D. 2010 Integrin alpha 6 regulates glioblastoma stem cells.. W& v- R7 X- Q1 S& r
Cell Stem Cell1 f' Q/ Z) Y) H& P; J6 X. F
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( V$ f5 A6 m/ b5 Z8 c# [, L3 X) bMa, S. 2010 miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.2 [! ] b' x1 k& i; v3 O0 l
Cell Stem Cell+ O# s- n" Q# R- q' i
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Pang, R. 2010 A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer.8 _& W. E2 e' U( \$ P, v
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+ g; z# b" d- x- Y/ mWurdak, H. 2010 An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.+ B+ k. y2 f% X1 f/ z) q2 ~
Cell Stem Cell1 p; l8 m7 Y( H) r: i4 _
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Yang, X. R. 2010 High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.
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7 J; K8 P& E/ w; c( i+ d1 GYou, H. 2010 Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta.4 e2 G+ b c! Z9 |# v7 r5 X
Hepatology; z# ^! W. c* x4 Q U
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" m! h& r, V$ k5 H7 ^9 d3 kCalcagno, A. M. 2010 Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics.
! _5 A8 ^9 d1 y1 P* j0 |J Natl Cancer Inst* [4 K2 y* C& } H* p3 H: F
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/ x+ H( Z% ^: o! a; X# kTehranchi, R. 2010 Persistent malignant stem cells in del(5q) myelodysplasia in remission.
* K* D1 Q/ [! m1 ]N Engl J Med
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Saito, Y. 2010 Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.# e7 O' _5 [" ~
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Vermeulen, L. 2010 Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
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3 ^* e; A- C) v) VYoussef, K. K. 2010 Identification of the cell lineage at the origin of basal cell carcinoma.9 M" x$ @ \% L7 P/ f1 O
Nat Cell Biol8 f8 N; R" l. w8 ~2 I* M( i
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Clément, V. 2010 Marker-independent identification of glioma-initiating cells.
9 z$ v) t) ~+ TNat Methods
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* t& T1 N$ G# x1 Z% G7 B# \Boiko, A. D. 2010 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. l* m k7 ]5 p9 p# N5 d p
Nature
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Naka, K. 2010 TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.
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Fillmore, C. M. 2010 Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.) {7 k$ d( O5 L7 o
Proc Natl Acad Sci U S A' D. B0 `( B. B# T
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J爀猀, M. 2010 Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.! n9 O, r. \5 V$ k
Proc Natl Acad Sci U S A
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4 z8 d. o( W+ u; ?Liu, H. 2010 Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models.
& c7 k: U. Q5 V2 v, F) A3 vProc Natl Acad Sci U S A
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& C R( \4 s; OMiyoshi, N. 2010 Defined factors induce reprogramming of gastrointestinal cancer cells.! R. a0 P) y6 i/ T% \3 g
Proc Natl Acad Sci U S A
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Mizuno, H. 2010 Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.+ _/ m% ~) _( w, n8 }; [ j
Proc Natl Acad Sci U S A
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% Z4 ~: Q2 G) B' Z+ RQiu, W. 2010 Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
7 N7 \) w# z8 k9 }( A" dProc Natl Acad Sci U S A! E, B3 a' G3 J9 k2 V! }3 W5 _) m
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Rouet, V. 2010 Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.6 Q3 Y. S1 W5 A" ]
Proc Natl Acad Sci U S A
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( r: L7 f8 m9 C, L: wYeung, T. M. 2010 Cancer stem cells from colorectal cancer-derived cell lines.
M2 q% a4 c5 j3 w" x7 p# XProc Natl Acad Sci U S A
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! }. F" y& k0 H4 k0 sZhang, M. 2010 Selective targeting of radiation-resistant tumor-initiating cells.- p! h4 m# }( S- L0 ?5 R7 I3 y! {5 c
Proc Natl Acad Sci U S A. }( a# N, t9 H v. ]
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7 U9 o! |, f, M# lWang, Y. 2010 The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
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Abou-Kheir, W. G. 2010 Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.
& ~' y/ u& T# H) g* SStem Cells
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deCarvalho, A. C. 2010 Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo.
* T" [/ ?1 F9 q* S/ l( TStem Cells( { X5 q& L" j& n0 b0 ?
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! I& q3 L9 R# D& gHovinga, K. E. 2010 Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.
! u1 r5 a+ k% v! E( W" L4 bStem Cells' ]0 z* c3 }$ h* V
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5 e: [; d8 a) \Hurt, E. M. 2010 Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.; q( @5 l/ `1 e% b) a
Stem Cells; L, j) K$ y' L* b# `
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Naka, N. 2010 Synovial sarcoma is a stem cell malignancy.
- y, x: S4 O) [( P; {Stem Cells
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Sajithlal, G. B. 2010 Permanently blocked stem cells derived from breast cancer cell lines.
% V9 ?. P& M+ z; \4 fStem Cells7 [$ n4 u% w: X( D5 K
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Stuelten, C. H. 2010 Complex display of putative tumor stem cell markers in the NCI60 tumor cell line panel.
% z5 w6 v( _& @' t o7 K2 ]Stem Cells
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6 q6 P0 U* G& X, [, c/ x; BSunayama, J. 2010 Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
! C' b Z/ Z$ I: j2 `8 \Stem Cells
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* D3 C) ]' z# U- U5 T! l$ [Wang, J. 2010 Notch promotes radioresistance of glioma stem cells.
- T* P& L$ S4 dStem Cells
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Watanabe, K. 2010 Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells." U- f2 C% T4 t# s9 c" A. J
Stem Cells
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