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从权威杂志 blood, cancer research, cancer cell, cell ,cell stem cell, cell research, stem cells, PNAS, nature 系列等收集了74篇研究性论文,与大家分享。
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Jiang, X. 2010 Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.3 q- ~/ w" u/ G7 C2 `& G
Blood
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6 Y& b1 t0 Y1 rPeng, C. 2010 PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.
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8 c" b/ P g# P# ~9 JSengupta, A. 2010 Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.
* z1 V5 i' e# L8 ~$ i7 O# NBlood5 _6 n( N) n* e# y" r& s( R
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Smith, A. C. 2010 High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.
6 k. j' C% K3 IBlood
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Taussig, D. C. 2010 Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
7 ?8 m* @, O t, Z# WBlood$ m1 I# F, l E1 j
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6 w. d) i2 J5 E2 W6 \# w9 w# a$ h( Q4 oChen, R. 2010 A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
/ |9 x. @. y7 d6 X4 tCancer Cell! N/ v+ _9 {3 M$ a* K) i2 F( P" u
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Yeung, J. 2010 β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.9 N3 T, V: U9 N
Cancer Cell
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Zhang, B. 2010 Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
8 Z! E, t! ?4 |! f- }" iCancer Cell
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3 a! R' `* Z2 f) `Biernacki, M. A. 2010 Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.0 g# K3 C# p! }! t/ c i: D
Cancer Res
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Bonnefoix, T. 2010 Cancer stem cells promote tumor vascular development--letter.5 b e2 R# v8 k4 l- G
Cancer Res
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' P! N! _* }2 O5 D# K5 mCammareri, P. 2010 Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.- y+ k/ @( t( o L/ f
Cancer Res! s9 |. i! q) Q
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Chiou, S. H. 2010 Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.) y0 i: t3 S( `! k" F
Cancer Res
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Deka, J. 2010 Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.$ j, b& J/ n- a) J( @8 H
Cancer Res& R) A! r2 j8 d/ V: @- r4 S* j
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Harrison, H. 2010 Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.
2 V- I$ q6 c$ | m6 g/ PCancer Res: [* A8 K) L) t3 W5 k6 h
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Hebbard, L. W. 2010 Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.
; q0 v; z9 \0 m- c$ }Cancer Res
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Held, M. A. 2010 Characterization of melanoma cells capable of propagating tumors from a single cell.
/ w) ^7 B/ n: I* V. m( r K9 SCancer Res: F( N3 x) m& H i% N
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, @; C! m4 T. a0 T9 `7 A: L2 aJin, Y. 2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
$ U6 j/ J8 o: \1 S8 c; OCancer Res
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Jo, M. 2010 Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
- o& @$ S1 v% l7 A; e* ICancer Res. H2 A1 G" n7 H, g4 l; ^
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! |/ h) B$ s0 |) JJoseph, I. 2010 The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.& g6 d7 h* V ^/ H6 n \
Cancer Res- J- i7 ]5 R0 B( [! `- D
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Kemper, K. 2010 The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation.0 w' Y; u# I4 K# a" x3 R
Cancer Res/ R& ]+ _2 I* b& {3 u B
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Krishnamurthy, S. 2010 Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells.! h' ^) D4 S# \
Cancer Res
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) Z1 Y. A7 {& z7 E$ k7 O- D8 DLee, J. H. 2010 Pathways of proliferation and antiapoptosis driven in breast cancer stem cells by stem cell protein piwil2.' b; \, |3 g% f- J2 |4 p
Cancer Res I1 w+ C% |1 e5 L a( ~. `
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Levina, V. 2010 Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop." k4 r$ t) }) k# h9 }, C
Cancer Res
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Liao, C. P. 2010 Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells.
9 H1 L& u) y5 W ICancer Res
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Liu, M. 2010 The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
2 w7 C0 ?' f. D6 B7 VCancer Res
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+ v2 X; V( G! zLottaz, C. 2010 Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.4 {! M) w9 B/ p2 `0 ?9 Y0 ^
Cancer Res, d6 x5 j; _8 Z! P
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+ b& ?1 g, f' N5 D3 N6 [2 r6 A1 O4 a% x; `Mazzoleni, S. 2010 Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.
s! U6 S& f+ Z. _. ` I0 \Cancer Res( a* Y& E. Z8 Y b6 o
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Ooi, A. T. 2010 Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
0 L: k! | C; S9 k& D5 x rCancer Res' K1 H$ ?+ \: J, \
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0 z/ c3 n9 S1 o! oReiman, J. M. 2010 Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.% k2 E/ P# a) O1 }; \1 i
Cancer Res
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Schatton, T. 2010 Modulation of T-cell activation by malignant melanoma initiating cells.
4 H( v' N- N8 P2 q6 NCancer Res8 v1 ]. {( Y0 w
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Sikandar, S. S. 2010 NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.- z4 f! a" p- [; u; o
Cancer Res* q/ f% G' L+ T/ R
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Sottoriva, A. 2010 Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.& _) f1 z- Y/ o7 P8 e' b2 W8 V) |6 N9 D
Cancer Res
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Sullivan, J. P. 2010 Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.5 p, M F* Z: ?
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Todaro, M. 2010 Tumorigenic and metastatic activity of human thyroid cancer stem cells.% t2 _( S# |0 ~% W3 ^) y6 j
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Wong, P. 2010 The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression.
: d- h- ~, |4 J5 R/ u* {2 }Cancer Res
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Yang, X. 2010 Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells.
k6 Z+ ]- n# o5 t% WCancer Res7 w( j; r% C& P- D* c8 K$ @' N
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Pece, S. 2010 Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.2 w& b2 h- Q3 l3 d( a+ Q: |+ D
Cell
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Roesch, A. 2010 A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
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& F T L: U3 E9 E! k; [9 BCharles, N. 2010 Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.
% R+ s* J6 h0 _$ T$ X1 M7 JCell Stem Cell
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& B3 }4 C8 n. [* P* V$ M* fKikushige, Y. 2010 TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells.6 T" u* w7 h9 h1 x X
Cell Stem Cell5 y+ s; X) @' T. l \9 F1 t
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Lathia, J. D. 2010 Integrin alpha 6 regulates glioblastoma stem cells.
. A3 L# n n+ r; cCell Stem Cell
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Ma, S. 2010 miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.
; G. P0 O- b: C: z5 u: BCell Stem Cell/ H/ E# V$ c( f+ ^# K# ]% N
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Pang, R. 2010 A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer.
; S% m+ h, i* [, yCell Stem Cell1 H2 q5 q/ A+ }7 V. T9 \5 t: a
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Wurdak, H. 2010 An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
+ }0 d4 l4 E H7 JCell Stem Cell
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Yang, X. R. 2010 High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.
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6 o7 s, N$ N4 `You, H. 2010 Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta.
9 b9 ]2 |( \( BHepatology: N7 b, L: W4 n( R
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Calcagno, A. M. 2010 Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics.
: l. j6 x0 ^! B4 }( F g' q4 eJ Natl Cancer Inst
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Tehranchi, R. 2010 Persistent malignant stem cells in del(5q) myelodysplasia in remission.
+ c* r' }" |+ B- v* kN Engl J Med. g: P& S1 a; Y" @& k7 D
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& j8 r" v- t2 J1 h* K; D2 j7 Z& oSaito, Y. 2010 Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.( B' W" a: ]$ ~: ?
Nat Biotechnol7 |$ v( w9 K7 p4 Y/ Z
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Vermeulen, L. 2010 Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.* I' z5 {* O. B. P. u1 {, \- S" ]
Nat Cell Biol
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* G. R9 n$ i6 t1 M4 PYoussef, K. K. 2010 Identification of the cell lineage at the origin of basal cell carcinoma.' P- F: {- b0 G$ c( [
Nat Cell Biol1 s: h- M: I2 ~- N- r# p
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$ U# h5 C- [5 \; ~* G- N3 xClément, V. 2010 Marker-independent identification of glioma-initiating cells.
8 }# R, |" Q7 g' C* sNat Methods' ~- Y% F+ Q0 e4 R# {# l) [5 X
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9 l% [+ @* h) t/ qBoiko, A. D. 2010 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271.
8 F5 G3 I8 ~6 r1 h6 |; w8 J0 nNature' m3 n# A, R# Z0 {4 I' Y" E
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x( Y, m- D; K. PNaka, K. 2010 TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.6 w) n- S! T. |1 c6 f$ f
Nature
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Fillmore, C. M. 2010 Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.3 v% y/ z) i8 x/ b- F
Proc Natl Acad Sci U S A
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6 `0 e. O0 V; v: O5 fJ爀猀, M. 2010 Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.9 T* M7 d; ^5 o/ N& H* r" }6 w
Proc Natl Acad Sci U S A
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Liu, H. 2010 Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models.
! Z- C) b/ G2 e6 YProc Natl Acad Sci U S A% h7 n1 |! k3 S- Q/ R
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' l% F, D# g7 }5 PMiyoshi, N. 2010 Defined factors induce reprogramming of gastrointestinal cancer cells.1 v4 E# X" w; ?& m+ t
Proc Natl Acad Sci U S A& p" W( M: T7 K1 a/ W% d* N0 `* q
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- |5 T+ X+ R) I4 X8 k8 |Mizuno, H. 2010 Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.# G; n0 L+ ~5 L c+ P o" x
Proc Natl Acad Sci U S A* s8 L3 n* j/ v# H% m
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# _8 G) N& @5 b1 [- K! E$ a( pQiu, W. 2010 Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.4 m5 K, s, j! |' I# `( O( X; v# @4 k
Proc Natl Acad Sci U S A
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1 ?' K' y! |+ G6 `# W! ARouet, V. 2010 Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.
3 e7 l* D' v6 Q" {Proc Natl Acad Sci U S A
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( E: n$ P% c0 ^. pYeung, T. M. 2010 Cancer stem cells from colorectal cancer-derived cell lines.
# X- t9 r9 h! h( \# U$ i3 E$ J- D/ U: ?Proc Natl Acad Sci U S A# H5 _, q; ~" L! h0 _
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Zhang, M. 2010 Selective targeting of radiation-resistant tumor-initiating cells.
/ D d, G/ F4 t" lProc Natl Acad Sci U S A/ \1 D, O/ x# b: _
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8 r1 T( j- V/ A& ~Wang, Y. 2010 The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
: x' ?) C/ y: VScience$ b: x: }$ T( {
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+ {1 F$ w n' I2 {: `6 ]Abou-Kheir, W. G. 2010 Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.% Q2 T; q& I7 O& c
Stem Cells; \$ W H; P8 s% H# N
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deCarvalho, A. C. 2010 Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo." l" h3 u8 f3 E& U$ I
Stem Cells/ _4 D/ t9 S `% g( P7 N
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Hovinga, K. E. 2010 Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.; o% Q- m6 _* p, t6 b, a. n3 S
Stem Cells
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9 ~" m" u. ~9 I, P* S7 aHurt, E. M. 2010 Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.9 `4 I/ c2 I6 p
Stem Cells
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Naka, N. 2010 Synovial sarcoma is a stem cell malignancy.
5 }! @! p$ h* ~8 z0 cStem Cells; M3 D: p, x* j$ t, B' H
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Sajithlal, G. B. 2010 Permanently blocked stem cells derived from breast cancer cell lines.6 X# C: t4 K- x e$ v: X* ^8 Y
Stem Cells! a! ~) b& v8 m8 ^9 ^7 s
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Stuelten, C. H. 2010 Complex display of putative tumor stem cell markers in the NCI60 tumor cell line panel.
7 B4 [4 a0 _, _( r- |4 dStem Cells
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Sunayama, J. 2010 Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.- l+ D( M6 U# V; q Z: @! e
Stem Cells- R, A" q. E& }% L
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8 W3 p x- A% n0 uWang, J. 2010 Notch promotes radioresistance of glioma stem cells.
3 X- b( J3 l+ p( a4 |! A$ BStem Cells
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4 K R3 {7 ^4 a$ ~( AWatanabe, K. 2010 Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.% z: z$ A2 m8 M6 x' @2 `& w7 b+ W
Stem Cells
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