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Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors 7 ^5 m( M! A6 m6 I$ Z4 n 5 H! X8 a% Q8 x" ohttp://www.ncbi.nlm.nih.gov/pubmed/22272626, c u3 n [5 {0 w5 d
The role of 5-hydroxymethylcytosine in aging and Alzheimer's disease: current status and prospects for future studies. 1 t4 Z7 b$ Y! s9 D) F& @ % n3 u2 \' P$ N4 n2 s Phttp://www.ncbi.nlm.nih.gov/pubmed/22272625 0 f& S. s$ J' Z( FAge-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction.