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http://www.ncbi.nlm.nih.gov/pubmed/22234893
: B' \5 f" o0 F7 J. ]Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors, Z: f6 ?0 e* d: p: H) j

% ~" p3 ?2 D$ n. y9 y  U* r1 ~6 Ahttp://www.ncbi.nlm.nih.gov/pubmed/22272626
2 z2 }" L3 H+ L# u6 I/ E- d6 [% L6 X0 wThe role of 5-hydroxymethylcytosine in aging and Alzheimer's disease: current status and prospects for future studies.
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) M: E$ R$ T* v! X5 ^  M0 Uhttp://www.ncbi.nlm.nih.gov/pubmed/22272625
5 Q" @) D' `+ a6 n6 R% O; wAge-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction.