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- 积分
- 331
- 威望
- 331
- 包包
- 218
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ERYTHROCYTE MATURATION . N1 W$ T) p4 C0 {% w' n$ v; J* u
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The overall trend in RBC maturation is large, pale nucleus to darker, smaller nucleus to loss of nucleus; increase in cytoplasm; gradual decrease in size; cytoplasm from intensely blue (full of RNA) to grayish (mixture of RNA and hemoglobin) to reddish (full of hemoglobin, no RNA). Identify the following cells.
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$ b4 Q* ~1 O! r! O1. Proerythroblast (14-19 µm): Nucleus is large with fine chromatin and nucleoli; cytoplasm is scant and basophilic.
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2. Basophilic erythroblast (12-17 µm): Slightly smaller nucleus with slight chromatin condensation; increased cytoplasm and intensely blue (RNA abundance); no granules and no nucleoli present.
* s9 O) G' E7 x1 F$ u, l7 S; b2 B
* X7 {4 M5 H0 L7 ]4 f% H" X3. Polychromatophilic erythroblast (12-15 µm): Moderately condensed chromatin; lighter, grayish cytoplasm. The color of the cytoplasm is due to coloring by both acidic and basic components of the stain. Basophilia is from staining of ribosomes and acidophilia from hemoglobin. The nucleus is condensed and intensely basophilic with coarse heterochromatin granules giving a characteristic checkerboard appearance. / P9 \( u g: J1 B- V3 D
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4. Orthochromatophilic erythroblast (8-12 µm): Dark, opaque nucleus; gray-red cytoplasm (trace blue). The nucleus has become pyknotic and there is abundant acidophilic hemoglobin. In some instances you can detect the nucleus in the process of extrusion.
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5. Reticulocyte (7-10 µm) [Not visible with this preparation. Refer to the laser disc to see an example.]: Nucleus has been extruded; cytoplasm is reddish-pale blue. RNA is still present. ( T* B9 q5 d9 j G5 n
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6. Erythrocyte (7-8 µm): No nucleus; orange-red cytoplasm; RNA is lost.8 w8 N& _" r( l3 D# j
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总评分: 威望 + 2
包包 + 10
查看全部评分
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发表于 2012-6-25 20:34
