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本帖最后由 细胞海洋 于 2012-8-3 15:11 编辑
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' ^- F ]: c: c& Y8 m《细胞》[Cell]12年7月20日出版pdf全文# O. V Y7 Y7 U) s( u8 [8 g. O, {
) M! H7 Y! v2 \9 i3 DVolume 150, Issue 2
5 g: R6 b; ~( y/ OOn the cover: At the blackboard. In this issue, Karr et al. (pp. 389–401)
# h. ^7 p# t* d0 O- D0 pdescribe construction of a whole-cell computational model for the human pathogen
7 b9 |! ]- r& o+ t/ |Mycoplasma genitalium. The model describes the expression and known 5 {5 N: L- n/ Z& I: s0 Q8 ^
function of each gene explicitly; is able to simulate experimentally measured
1 H7 I, l4 c: `6 ?% Yphenotypes; and offers new insights into the interplay between biological " y% ]) U* u" e/ p, M
pathways. The cover features a chalkboard filled with equations and diagrams—all
1 Z) w2 M9 O8 Yof which represent principles and concepts incorporated into the whole-cell
' _* A. l% k# R/ M: z" jmodel. Blackboard art by corresponding author Markus Covert. Photography and
) F4 S' D" q+ x. N6 t5 \0 ~$ z8 ndesign by Threestory Studio.
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