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本帖最后由 细胞海洋 于 2012-8-3 15:11 编辑 ( R& Q- l3 j$ W+ D% E
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《细胞》[Cell]12年7月20日出版pdf全文
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; v' A" _ N7 T# s! n1 J t+ T* L6 ZVolume 150, Issue 2' S- O: {1 C5 ?) U/ u
On the cover: At the blackboard. In this issue, Karr et al. (pp. 389–401) 6 B* V2 C/ y" F* [2 U! m& {4 a
describe construction of a whole-cell computational model for the human pathogen
7 X8 J! t+ w& f; ~& w, L: u1 h2 VMycoplasma genitalium. The model describes the expression and known $ S6 ~: e6 }* @/ q4 F
function of each gene explicitly; is able to simulate experimentally measured * t! X0 F/ z9 x% {
phenotypes; and offers new insights into the interplay between biological ' c/ u# k4 U C: r% g0 U
pathways. The cover features a chalkboard filled with equations and diagrams—all / r ^2 D# q8 Y4 a5 O/ S
of which represent principles and concepts incorporated into the whole-cell
* h) O, R/ L8 i2 H4 I5 ~* Pmodel. Blackboard art by corresponding author Markus Covert. Photography and 8 G: E4 q& L8 @6 i
design by Threestory Studio.7 t9 J4 B0 y8 n) ?! u, l p/ U
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