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本帖最后由 细胞海洋 于 2012-8-3 15:11 编辑
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《细胞》[Cell]12年7月20日出版pdf全文
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% w' x% Q2 r8 v) ]/ WVolume 150, Issue 23 b; _- |! i2 j- f! e7 U1 Q7 k
On the cover: At the blackboard. In this issue, Karr et al. (pp. 389–401) / b; F }/ u2 ?. O; d
describe construction of a whole-cell computational model for the human pathogen 9 c. u- `4 m9 @) t* ~
Mycoplasma genitalium. The model describes the expression and known
; d9 I, z" j- N2 ^; j3 Dfunction of each gene explicitly; is able to simulate experimentally measured
: t2 ]$ l" r) Gphenotypes; and offers new insights into the interplay between biological
. n- d+ r9 [" ]2 a$ m1 x8 ]pathways. The cover features a chalkboard filled with equations and diagrams—all
- }4 u9 ?0 e# f4 v" U: Bof which represent principles and concepts incorporated into the whole-cell
: g- n! N6 R9 @1 n/ Z2 ^model. Blackboard art by corresponding author Markus Covert. Photography and - t) }2 n. J2 ~! i4 P! ^
design by Threestory Studio.' j, U) {* |) o; `- e
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/ ?% |; Z1 i5 R" w8 |[hide][/hide] |
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