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本帖最后由 细胞海洋 于 2012-8-3 15:11 编辑 6 g2 T- `" e& W V- L& r" O
* b: H$ h( E) j: Z! m, \4 {. [《细胞》[Cell]12年7月20日出版pdf全文% J1 p" ?( A5 D7 a
6 K! y, a; V% A5 i# J/ S5 F! |; tVolume 150, Issue 2
# Y+ e( k5 B+ Z) DOn the cover: At the blackboard. In this issue, Karr et al. (pp. 389–401) 4 j) n' ~# |) N) E( J
describe construction of a whole-cell computational model for the human pathogen 5 c7 }6 t& h! @
Mycoplasma genitalium. The model describes the expression and known . h; ?) G# U I
function of each gene explicitly; is able to simulate experimentally measured
$ Y! \8 f/ H' X" m- P# {phenotypes; and offers new insights into the interplay between biological
- O1 q' f- n7 M. epathways. The cover features a chalkboard filled with equations and diagrams—all 4 v& E0 l6 o& K" A: |/ F! `3 f6 M t
of which represent principles and concepts incorporated into the whole-cell & I/ {0 e# o) i
model. Blackboard art by corresponding author Markus Covert. Photography and
& R' C8 c9 a. Ndesign by Threestory Studio.# I- a1 S/ _, x, Z0 Z* M
; k- S6 m5 Z6 C$ J' H; Q5 F) f' ]+ f7 g3 h6 P9 S3 {
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