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如题,要包含下面这段话(本人写文时引用的,但是不知道是哪篇了,找不到 )
1 w3 Z' m. |8 g5 w8 f; J) S& bInflammation and immunity may be involved in the etiology and pathogenesis of schizophrenia and major mood disorders. There is evidence of both proinflammatory activation of the innate immune System and an activation of the T-cells of the adaptive immune system in both schizophrenia and bipolar disorder. This activation is reflected in alterations in circulating inflammatory cytokines. Elevated cytokine levels might lead to psychiatric symptoms through several mechanisms. Cytokines are involved in neuronal cell survival, neural stem cell renewal, differentiation and brain repair, and in monoamine neurotransmitter metabolism. Some cytokines have stressor-like effects on CNS, including changes in tryptophan metabolism, hypothalamo–pituitary–adrenocortical axis, and brain-derived neurotrophic factor expression. |
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