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2012年11月 Nature Medicine$ {2 i2 T E. q0 T( e. D
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In this issue, Andrew Weng and his colleagues uncover a new
) S- i6 r/ {8 P, Mmechanism by which oncogenes regulate leukemia stem cells. Notch-driven ! j: L( w* @( J4 E
inactivation of PKCθ attenuates the accumulation of * s# f' ^$ X" u" O
reactive oxygen species to lower oxidative stress in the stem cell population of
0 e# ~3 T8 S/ i, h3 d* nT cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The 6 }+ R* l" f0 C @* g- O, ]: @1 {
image shows an electron micrograph of erythrocytes and lymphocytes from a / h" z8 I; Q, Y |+ j! P' `: a) v/ b
patient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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/ K4 ^: M. }' Q[hide][/hide] |
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
